{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T21:06:52Z","timestamp":1789247212708,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T00:00:00Z","timestamp":1782259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Research Project on the Health Effects of Radiation, organized by the Ministry of Environment, Japan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It has been hypothesized that the incidence of cryptorchidism may have increased in Japan following the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident in March 2011; however, empirical evidence remains limited. This study aimed to assess the possible impact of the accident on cryptorchidism incidence over an extended period of time before and after the accident.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Detailed information on all patients who underwent orchiopexy between April 2008 and March 2021 was obtained from the medical records of 86 hospitals in Fukushima Prefecture. Interrupted time series analyses were performed to evaluate the immediate post- versus pre-accident level change and the monthly post- versus pre-accident slope change in orchiopexy surgery rates and birth rates with cryptorchidism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 622 orchiopexy surgeries performed in Fukushima Prefecture during the study period were included. No significant increase was observed in the monthly orchiopexy surgery rate per 100\u00a0000 population in Fukushima Prefecture after the accident, in terms of either the immediate level change (incidence rate ratio [IRR], 1.21; 95% CI, 0.86\u20131.70) or the monthly slope change (IRR per month, 1.01; 95% CI, 0.99\u20131.04). The estimated monthly birth rate with cryptorchidism per 1000 live births in Fukushima Prefecture also showed no significant increase in either the immediate level change (IRR, 0.87; 95% CI, 0.52\u20131.44) or the monthly slope change (IRR per month, 1.01; 95% CI, 0.99\u20131.04).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study provided no evidence that the FDNPP accident increased the orchiopexy surgery rates or birth rates with cryptorchidism in Fukushima Prefecture.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ije\/dyag114","type":"journal-article","created":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T07:06:14Z","timestamp":1784358374000},"source":"Crossref","is-referenced-by-count":0,"title":["The Fukushima Daiichi Nuclear Power Plant accident did not increase the incidence of cryptorchidism: an interrupted time series analysis"],"prefix":"10.1093","volume":"55","author":[{"given":"Yuichi","family":"Sato","sequence":"first","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0109-7425","authenticated-orcid":false,"given":"Kenji","family":"Omae","sequence":"additional","affiliation":[{"name":"Department of Innovative Research and Education for Clinicians and Trainees (DiRECT), Fukushima Medical University Hospital , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soichiro","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Kirihana","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Yaginuma","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihisa","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Natsuya","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Hakozaki","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Meguro","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Tanji","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruriko","family":"Takinami-Honda","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , 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Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9608-3669","authenticated-orcid":false,"given":"Tetsuo","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Radiation Physics and Chemistry, Fukushima Medical University , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Fukushima Medical University Hospital , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Shimura","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Yamanashi Graduate School of Medical Sciences , Yamanashi,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanori","family":"Mochizuki","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Yamanashi Graduate School of Medical Sciences , Yamanashi,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noboru","family":"Oyachi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Yamanashi Prefectural Central Hospital , Yamanashi,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Mitsui","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Yamanashi Graduate School of Medical Sciences , 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(DiRECT), Fukushima Medical University Hospital , Fukushima,","place":["Japan"]},{"name":"Department of Clinical Epidemiology, Graduate School of Medicine, Fukushima Medical University , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Kojima","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukushima Medical University School of Medicine , Fukushima,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,17]]},"reference":[{"key":"2026091216224196400_dyag114-B1","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/nrurol.2017.90","article-title":"Risk factors for cryptorchidism","volume":"14","author":"Gurney","year":"2017","journal-title":"Nat Rev Urol"},{"key":"2026091216224196400_dyag114-B2","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.urology.2009.04.037","article-title":"Advances in 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