{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T10:03:48Z","timestamp":1789639428234,"version":"4.0.0"},"reference-count":68,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Epidemiol."],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1093\/ije\/dyw147","type":"journal-article","created":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T22:08:57Z","timestamp":1471558137000},"page":"1445-1457","source":"Crossref","is-referenced-by-count":93,"title":["Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence"],"prefix":"10.1093","volume":"45","author":[{"given":"Qin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"W\u00fcrtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsi","family":"Auro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Morin-Papunen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antti J","family":"Kangas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasi","family":"Soininen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Tiainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuulia","family":"Tynkkynen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anni","family":"Joensuu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki S","family":"Havulinna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristiina","family":"Aalto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marko","family":"Salmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Blankenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Zeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorma","family":"Viikari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"K\u00e4h\u00f6nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terho","family":"Lehtim\u00e4ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veikko","family":"Salomaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirpa","family":"Jalkanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjo-Riitta","family":"J\u00e4rvelin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Perola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olli T","family":"Raitakari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debbie A","family":"Lawlor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Kettunen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Ala-Korpela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,8,18]]},"reference":[{"key":"2016110804475415000_45.5.1445.1","first-page":"1","article-title":"Contraceptive methods women have ever used: United States, 1982\u20132010","volume":"14","author":"Daniels","year":"2013","journal-title":"Natl Health Stat Report"},{"key":"2016110804475415000_45.5.1445.2","doi-asserted-by":"publisher","DOI":"10.3109\/13625187.2010.533002"},{"key":"2016110804475415000_45.5.1445.3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d6423"},{"key":"2016110804475415000_45.5.1445.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2012.11.002"},{"key":"2016110804475415000_45.5.1445.5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f5298"},{"key":"2016110804475415000_45.5.1445.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1111840"},{"key":"2016110804475415000_45.5.1445.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2012.11.003"},{"key":"2016110804475415000_45.5.1445.8","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200060040-00003"},{"key":"2016110804475415000_45.5.1445.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2012.09.004"},{"key":"2016110804475415000_45.5.1445.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.04.013"},{"key":"2016110804475415000_45.5.1445.11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199011153232003"},{"key":"2016110804475415000_45.5.1445.12","doi-asserted-by":"publisher","DOI":"10.1080\/00365510802449642"},{"key":"2016110804475415000_45.5.1445.13","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-04-1285"},{"key":"2016110804475415000_45.5.1445.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2011.09.014"},{"key":"2016110804475415000_45.5.1445.15","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-0026"},{"key":"2016110804475415000_45.5.1445.16","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1538-7836.2005.01690.x","article-title":"Treatment with combined oral contraceptives induces a rise in serum C-reactive protein in the absence of a general inflammatory response","volume":"4","author":"van Rooijen","year":"2006","journal-title":"J Thromb Haemost"},{"key":"2016110804475415000_45.5.1445.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2004.08.002"},{"key":"2016110804475415000_45.5.1445.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2004.06.001"},{"key":"2016110804475415000_45.5.1445.19","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000148304.33869.ee"},{"key":"2016110804475415000_45.5.1445.20","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dym225"},{"key":"2016110804475415000_45.5.1445.21","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.901413"},{"key":"2016110804475415000_45.5.1445.22","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h2135"},{"key":"2016110804475415000_45.5.1445.23","doi-asserted-by":"publisher","DOI":"10.1039\/b910205a"},{"key":"2016110804475415000_45.5.1445.24","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.114.000216"},{"key":"2016110804475415000_45.5.1445.25","doi-asserted-by":"publisher","DOI":"10.2337\/db11-1355"},{"key":"2016110804475415000_45.5.1445.26","doi-asserted-by":"publisher","DOI":"10.1038\/ng.1073"},{"key":"2016110804475415000_45.5.1445.27","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.105551"},{"key":"2016110804475415000_45.5.1445.28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001606"},{"key":"2016110804475415000_45.5.1445.29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001765"},{"key":"2016110804475415000_45.5.1445.30","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.013116"},{"key":"2016110804475415000_45.5.1445.31","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyv093"},{"key":"2016110804475415000_45.5.1445.32","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2010.93"},{"key":"2016110804475415000_45.5.1445.33","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34242-6"},{"key":"2016110804475415000_45.5.1445.34","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5708"},{"key":"2016110804475415000_45.5.1445.35","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-0895"},{"key":"2016110804475415000_45.5.1445.36","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-0800"},{"key":"2016110804475415000_45.5.1445.37","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-7824(01)00224-4"},{"key":"2016110804475415000_45.5.1445.38","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-014-0507-4"},{"key":"2016110804475415000_45.5.1445.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2003.10.004"},{"key":"2016110804475415000_45.5.1445.40","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-7824(02)00537-1"},{"key":"2016110804475415000_45.5.1445.41","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61177-6"},{"key":"2016110804475415000_45.5.1445.42","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2795"},{"key":"2016110804475415000_45.5.1445.43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.08.1026"},{"key":"2016110804475415000_45.5.1445.44","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(12)60312-2","article-title":"Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study","volume":"380","author":"Voight","year":"2012","journal-title":"The Lancet"},{"key":"2016110804475415000_45.5.1445.45","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1206797"},{"key":"2016110804475415000_45.5.1445.46","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad3517"},{"key":"2016110804475415000_45.5.1445.47","doi-asserted-by":"publisher","DOI":"10.7326\/M13-1788."},{"key":"2016110804475415000_45.5.1445.48","doi-asserted-by":"publisher","DOI":"10.1038\/msb4100205"},{"key":"2016110804475415000_45.5.1445.49","first-page":"614","article-title":"Serum metabolomic profiles suggest influence of sex and oral contraceptive use","volume":"6","author":"Ruoppolo","year":"2014","journal-title":"American Journal of Translational Research"},{"key":"2016110804475415000_45.5.1445.50","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1093\/ajcn\/31.5.794","article-title":"Effect of oral alanine loads on plasma amino acids in oral contraceptive users and control women","volume":"31","author":"Potera","year":"1978","journal-title":"Am J Clin Nutr"},{"key":"2016110804475415000_45.5.1445.51","doi-asserted-by":"publisher","DOI":"10.1042\/cs0410301"},{"key":"2016110804475415000_45.5.1445.52","doi-asserted-by":"publisher","DOI":"10.1007\/s002280050089"},{"key":"2016110804475415000_45.5.1445.53","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(94)00502-J"},{"key":"2016110804475415000_45.5.1445.54","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00778.x"},{"key":"2016110804475415000_45.5.1445.55","doi-asserted-by":"crossref","first-page":"1586S","DOI":"10.1093\/jn\/137.6.1586S","article-title":"Phenylalanine and tyrosine metabolism in chronic kidney failure","volume":"137","author":"Kopple","year":"2007","journal-title":"J Nutr"},{"key":"2016110804475415000_45.5.1445.56","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.3.1242"},{"key":"2016110804475415000_45.5.1445.57","doi-asserted-by":"publisher","DOI":"10.1210\/jc.80.6.1816"},{"key":"2016110804475415000_45.5.1445.58","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1114248"},{"key":"2016110804475415000_45.5.1445.59","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0140-6736(13)60595-4","article-title":"Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention","volume":"382","author":"Gansevoort","year":"2013","journal-title":"The Lancet"},{"key":"2016110804475415000_45.5.1445.60","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707402"},{"key":"2016110804475415000_45.5.1445.61","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.954"},{"key":"2016110804475415000_45.5.1445.62","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g6330"},{"key":"2016110804475415000_45.5.1445.63","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.113.082602"},{"key":"2016110804475415000_45.5.1445.64","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012477"},{"key":"2016110804475415000_45.5.1445.65","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12054"},{"key":"2016110804475415000_45.5.1445.66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037815"},{"key":"2016110804475415000_45.5.1445.67","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2015.102"},{"key":"2016110804475415000_45.5.1445.68","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxt006"}],"container-title":["International Journal of Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ije\/article-pdf\/45\/5\/1445\/14154824\/dyw147.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T13:59:34Z","timestamp":1568296774000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ije\/article-lookup\/doi\/10.1093\/ije\/dyw147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,18]]},"references-count":68,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,11,8]]},"published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1093\/ije\/dyw147"],"URL":"https:\/\/doi.org\/10.1093\/ije\/dyw147","relation":{},"ISSN":["0300-5771","1464-3685"],"issn-type":[{"value":"0300-5771","type":"print"},{"value":"1464-3685","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,18]]}}}