{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T12:40:44Z","timestamp":1793191244539,"version":"4.5.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2019,3,30]],"date-time":"2019-03-30T00:00:00Z","timestamp":1553904000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Bureau of Health Promotion, Department of Health, Taiwan","award":["BHP-PHRC-92\u20134"],"award-info":[{"award-number":["BHP-PHRC-92\u20134"]}]},{"name":"Bureau of Health Promotion, Department of Health, Taiwan","award":["DOH93-HP-1702"],"award-info":[{"award-number":["DOH93-HP-1702"]}]},{"name":"Bureau of Health Promotion, Department of Health, Taiwan","award":["DOH94-HP-1802"],"award-info":[{"award-number":["DOH94-HP-1802"]}]},{"name":"Bureau of Health Promotion, Department of Health, Taiwan","award":["DOH95-HP-1802"],"award-info":[{"award-number":["DOH95-HP-1802"]}]},{"name":"Bureau of Health Promotion, Department of Health, Taiwan","award":["DOH96-HP-1702"],"award-info":[{"award-number":["DOH96-HP-1702"]}]},{"name":"Bureau of Health Promotion, Department of Health, Taiwan","award":["MOST 105\u20132314-B-002\u2013048-MY2"],"award-info":[{"award-number":["MOST 105\u20132314-B-002\u2013048-MY2"]}]},{"name":"Bureau of Health Promotion, Department of Health, Taiwan","award":["MOST 107\u20132314-B-002\u2013182-MY3"],"award-info":[{"award-number":["MOST 107\u20132314-B-002\u2013182-MY3"]}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["MOST 107\u20133017-F-002\u2013003"],"award-info":[{"award-number":["MOST 107\u20133017-F-002\u2013003"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Higher Education Sprout Project by the Ministry of Education in Taiwan","award":["NTU-107L9003"],"award-info":[{"award-number":["NTU-107L9003"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Maternal shift work is associated with preterm delivery, small-for-gestational-age new-borns, childhood obesity and future behavioural problems. However, the adverse effects on and interactions of maternal shift work with infant neurodevelopment remain uncertain. Therefore, we examined the associations between maternal-shift-work status and infant neurodevelopmental parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Taiwan Birth Cohort Study is a nationwide birth cohort study following representatively sampled mother\u2013infant pairs in 2005. The participants\u2019 development and exposure conditions were assessed by home interviews with structured questionnaires at 6 and 18\u2009months of age. Propensity scores were calculated with predefined covariates for 1:1 matching. Multivariate conditional logistic regression and the Cox proportional-hazards model were used to examine the association between maternal-shift-work status and infant neurodevelopmental-milestone-achievement status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this study, 5637 term singletons were included, with 2098 cases selected in the propensity-score-matched subpopulation. Persistent maternal shift work was associated with increased risks of delays in gross-motor neurodevelopmental milestones [aOR\u2009=\u20091.36, 95% confidence interval (CI)\u2009=\u20091.06\u20131.76 for walking steadily], fine-motor neurodevelopmental milestones (aOR\u2009=\u20091.39, 95% CI\u2009=\u20091.07\u20131.80 for scribbling) and social neurodevelopmental milestones (aOR\u2009=\u20091.35, 95% CI\u2009=\u20091.03\u20131.76 for coming when called upon). Moreover, delayed gross-motor and social development were identified in the propensity-score-matched sub-cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study shows negative associations between maternal shift work and delayed neurodevelopmental-milestone achievement in the gross-motor, fine-motor and social domains at 18\u2009months. Future research is necessary to elucidate the possible underlying mechanisms and long-term health effects.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ije\/dyz045","type":"journal-article","created":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T12:17:57Z","timestamp":1552479477000},"page":"1545-1555","source":"Crossref","is-referenced-by-count":11,"title":["Association between maternal shift work and infant neurodevelopmental outcomes: results from the Taiwan Birth Cohort Study with propensity-score-matching analysis"],"prefix":"10.1093","volume":"48","author":[{"given":"Chih-Fu","family":"Wei","sequence":"first","affiliation":[{"name":"Institute of Environmental and Occupational Health Sciences, National Taiwan University College of Public Health, Taipei, Taiwan"},{"name":"Department of Environmental and Occupational Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Huei","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan"},{"name":"Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Chun","family":"Lin","sequence":"additional","affiliation":[{"name":"Institute of Environmental and Occupational Health Sciences, National Taiwan University College of Public Health, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueliang Leon","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute of Environmental and Occupational Health Sciences, National Taiwan University College of Public Health, Taipei, Taiwan"},{"name":"Department of Environmental and Occupational Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan"},{"name":"National Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shio-Jean","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chi Mei Medical Center, Tainan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Fang","family":"Liao","sequence":"additional","affiliation":[{"name":"School of Physical Therapy, National Taiwan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu-Shiun","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan"},{"name":"Department of Pediatrics, Cathay General Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6242-5974","authenticated-orcid":false,"given":"Pau-Chung","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Environmental and Occupational Health Sciences, National Taiwan University College of Public Health, Taipei, Taiwan"},{"name":"Department of Environmental and Occupational Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan"},{"name":"Department of Public Health, National Taiwan University College of Public Health, Taipei, Taiwan"},{"name":"Office of Occupational Safety and Health, National Taiwan University Hospital, Taipei, Taiwan"},{"name":"Innovation and Policy Center for Population Health and Sustainable Environment, National Taiwan University College of Public Health, Taipei, 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