{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T02:23:48Z","timestamp":1792981428103,"version":"4.5.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T00:00:00Z","timestamp":1728864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To assess the content and frequency of advice community pharmacists (CPs) provide to pregnant women with nausea and vomiting, their confidence in providing advice, and their knowledge of the safety of medication used to manage the condition.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>An online questionnaire of closed- and open-ended questions was distributed to CPs in the UK in May 2023. Closed-ended questions were analysed quantitatively, and conventional content analysis was utilised for open-ended responses.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Key findings<\/jats:title>\n                  <jats:p>One hundred and eighty-one respondents completed the questionnaire, 24 responses were excluded, leaving data from 157 available for analysis. The majority (90.4%) of participants reported having experience in providing advice on nausea and vomiting with varying levels of confidence. Advice provided included using over-the-counter products, lifestyle modifications, reassurance, medication advice, and referring to other healthcare professionals. Knowledge of first-line antiemetics considered safe in pregnancy varied; cyclizine was correctly identified as safe during pregnancy by 57.3%, followed by 37.6% for promethazine and 31.2% for prochlorperazine. Self-reported confidence and having experience providing advice were related to higher medication safety identification rates. Five percent of participants reported previous training on the condition, while 70% reported wanting further education, preferably delivered via an online medium.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study showed that although 90% of CPs provide advice on nausea and vomiting in pregnancy, their medication safety knowledge varied. The majority of CPs reported wanting further education that would ensure women could access reliable information and evidence-based advice to optimise management of the condition.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ijpp\/riae057","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T18:32:11Z","timestamp":1728930731000},"page":"45-51","source":"Crossref","is-referenced-by-count":4,"title":["Nausea and vomiting in pregnancy: a cross-sectional study of community pharmacists in the UK"],"prefix":"10.1093","volume":"33","author":[{"given":"Bradley","family":"Payne","sequence":"first","affiliation":[{"name":"Department of Women & Children\u2019s Health, School of Life Course & Population Sciences, King\u2019s College London , St Thomas\u2019 Hospital, Westminster Bridge Road, London, SE1 7EH ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Righton","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, King\u2019s College London , Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Nana","sequence":"additional","affiliation":[{"name":"Department of Women & Children\u2019s Health, School of Life Course & Population Sciences, King\u2019s College London , St Thomas\u2019 Hospital, Westminster Bridge Road, London, SE1 7EH ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Chapman","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Science, King\u2019s College London , Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Williamson","sequence":"additional","affiliation":[{"name":"Institute of Reproductive and Developmental Biology, Imperial College London , Hammersmith Hospital, 72 Du Cane Road, London, W12 0NN ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivali","family":"Lakhani","sequence":"additional","affiliation":[{"name":"The Middlesex Pharmaceutical Group of LPCs , 1278 High Road, Whetstone, London N20 9HH ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marsha","family":"Alter","sequence":"additional","affiliation":[{"name":"The Middlesex Pharmaceutical Group of LPCs , 1278 High Road, Whetstone, London N20 9HH ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Bell","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences, School of Life Course & Population Sciences, King\u2019s College London , Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8438-1506","authenticated-orcid":false,"given":"Angela C","family":"Flynn","sequence":"additional","affiliation":[{"name":"School of Population Health, Royal College of Surgeons in Ireland, Beaux Lane House , Lower Mercer Street, Dublin 2, D02 DH60 ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,14]]},"reference":[{"key":"2025020709413948900_CIT0001","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1002\/ncp.10205","article-title":"Hyperemesis Gravidarum","volume":"34","author":"Austin","year":"2019","journal-title":"Nutr Clin Pract"},{"key":"2025020709413948900_CIT0002","first-page":"1405","article-title":"Nausea and vomiting in early pregnancy","volume":"2014","author":"Festin","year":"2014","journal-title":"BMJ Clin Evid"},{"key":"2025020709413948900_CIT0003","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1038\/s41572-019-0110-3","article-title":"Nausea and vomiting of pregnancy and hyperemesis gravidarum","volume":"5","author":"Fejzo","year":"2019","journal-title":"Nat Rev Dis Primers"},{"key":"2025020709413948900_CIT0004","volume-title":"Hyperemesis Gravidarum. StatPearls","author":"Jennings","year":"2023"},{"key":"2025020709413948900_CIT0005","doi-asserted-by":"publisher","first-page":"2492","DOI":"10.1080\/14767058.2017.1342805","article-title":"Interventions for treating hyperemesis gravidarum: a Cochrane systematic review and meta-analysis","volume":"31","author":"Boelig","year":"2018","journal-title":"J Matern Fetal Neonatal Med"},{"key":"2025020709413948900_CIT0006","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1017\/S0954422421000305","article-title":"Nutritional consequences and management of hyperemesis gravidarum: a narrative review","volume":"35","author":"Maslin","year":"2022","journal-title":"Nutr Res Rev"},{"key":"2025020709413948900_CIT0007","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1177\/1753495X211040926","article-title":"Termination of wanted pregnancy and suicidal ideation in hyperemesis gravidarum: a mixed methods study","volume":"15","author":"Nana","year":"2022","journal-title":"Obstet Med"},{"key":"2025020709413948900_CIT0008","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1038\/sj.jp.7211906","article-title":"The psychosocial burden of hyperemesis gravidarum","volume":"28","author":"Poursharif","year":"2008","journal-title":"J Perinatol"},{"key":"2025020709413948900_CIT0009","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1080\/01443615.2019.1572725","article-title":"The relationship of hyperemesis gravidarum with sleep disorders, anxiety and depression","volume":"39","author":"Y\u0131ld\u0131r\u0131m","year":"2019","journal-title":"J Obstet Gynaecol"},{"key":"2025020709413948900_CIT0010","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.ajog.2021.03.006","article-title":"Hyperemesis gravidarum is associated with increased rates of termination of pregnancy and suicidal ideation: results from a survey completed by &gt;5000 participants","volume":"224","author":"Nana","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"2025020709413948900_CIT0011","author":"RCOG","journal-title":"The Management of Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum 2016 [Green top guidelines]"},{"key":"2025020709413948900_CIT0012","doi-asserted-by":"publisher","first-page":"BJGPO.2021.0119","DOI":"10.3399\/BJGPO.2021.0119","article-title":"Hyperemesis gravidarum in the primary care setting: cross-sectional study of GPs","volume":"6","author":"Nana","year":"2022","journal-title":"BJGP Open"},{"key":"2025020709413948900_CIT0013","doi-asserted-by":"publisher","first-page":"e002594","DOI":"10.1136\/bmjopen-2013-002594","article-title":"Medicines information needs during pregnancy: a multinational comparison","volume":"3","author":"H\u00e4meen-Anttila","year":"2013","journal-title":"BMJ Open"},{"key":"2025020709413948900_CIT0014","doi-asserted-by":"publisher","first-page":"e067987","DOI":"10.1136\/bmjopen-2022-067987","article-title":"Women\u2019s experiences of over-the-counter and prescription medication during pregnancy in the UK: findings from survey free-text responses and narrative interviews","volume":"13","author":"Sanders","year":"2023","journal-title":"BMJ Open"},{"key":"2025020709413948900_CIT0015","doi-asserted-by":"publisher","first-page":"e0219424","DOI":"10.1371\/journal.pone.0219424","article-title":"Community pharmacist counseling in early pregnancy\u2014results from the SafeStart feasibility study","volume":"14","author":"Truong","year":"2019","journal-title":"PLoS One"},{"key":"2025020709413948900_CIT0016","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1186\/s12884-020-03472-z","article-title":"The effect of a pharmacist consultation on pregnant women\u2019s quality of life with a special focus on nausea and vomiting: an intervention study","volume":"20","author":"Truong","year":"2020","journal-title":"BMC Pregnancy Childbirth"},{"key":"2025020709413948900_CIT0017","first-page":"1","article-title":"Demographic and psychological predictors of community pharmacists\u2019 cancer-related conversations with patients: a cross-sectional analysis and survey study","volume":"22","author":"Kerrison","year":"2022","journal-title":"BMC Health Serv Res"},{"key":"2025020709413948900_CIT0018","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1177\/1049732305276687","article-title":"Three approaches to qualitative content analysis","volume":"15","author":"Hsieh","year":"2005","journal-title":"Qual Health Res"},{"key":"2025020709413948900_CIT0019","year":"2023"},{"key":"2025020709413948900_CIT0020","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1016\/j.jsps.2017.05.005","article-title":"Knowledge of community pharmacists about the risks of medication use during pregnancy in central region of Saudi Arabia","volume":"25","author":"Alrabiah","year":"2017","journal-title":"Saudi Pharm J"},{"key":"2025020709413948900_CIT0021","doi-asserted-by":"crossref","first-page":"215","DOI":"10.5530\/ijpi.2019.4.40","article-title":"Knowledge, attitude and practice of community pharmacists on medication safety during pregnancy: a cross-sectional study","volume":"9","author":"Narayana","year":"2019","journal-title":"Int J Pharm Investig"},{"key":"2025020709413948900_CIT0022","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1007\/s11096-015-0111-6","article-title":"Experiences of community pharmacists advising pregnant women","volume":"37","author":"Grincevi\u010dien\u0117","year":"2015","journal-title":"Int J Clin Pharm"},{"key":"2025020709413948900_CIT0023","doi-asserted-by":"publisher","first-page":"137","DOI":"10.26719\/2018.24.2.137","article-title":"Knowledge and practice characteristics of pharmacists in Qatar towards medication use in pregnancy: a cross-sectional survey","volume":"24","author":"Abdul Rouf","year":"2018","journal-title":"East Mediterr Health J"},{"key":"2025020709413948900_CIT0024","doi-asserted-by":"publisher","first-page":"e018980","DOI":"10.1136\/bmjopen-2017-018980","article-title":"Community pharmacists\u2019 services for women during pregnancy and breast feeding in Kuwait: a cross-sectional study","volume":"8","author":"Albassam","year":"2018","journal-title":"BMJ Open"},{"key":"2025020709413948900_CIT0025","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.midw.2007.05.002","article-title":"Nausea and vomiting in pregnancy: what advice do midwives give","volume":"24","author":"Wills","year":"2008","journal-title":"Midwifery"},{"key":"2025020709413948900_CIT0026","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.explore.2006.06.002","article-title":"Meta-analysis of acustimulation effects on nausea and vomiting in pregnant women","volume":"2","author":"Helmreich","year":"2006","journal-title":"Explore (NY)"},{"key":"2025020709413948900_CIT0027","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/hta20740","article-title":"Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: a systematic review and economic assessment","volume":"20","author":"O\u2019Donnell","year":"2016","journal-title":"Health Technol Assess"},{"key":"2025020709413948900_CIT0028","author":"WHO","journal-title":"WHO Recommendations on Antenatal Care for a Positive Pregnancy Experience 2017 [WHO Maternal Guidelines of NVP]"},{"key":"2025020709413948900_CIT0029","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1111\/ajo.13359","article-title":"Pregnant women report being denied medications to treat severe nausea and vomiting of pregnancy or hyperemesis gravidarum\u2014findings from an Australian online survey","volume":"61","author":"Hsiao","year":"2021","journal-title":"Aust N Z J Obstet Gynaecol"}],"container-title":["International Journal of Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ijpp\/article-pdf\/33\/1\/45\/59832012\/riae057.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ijpp\/article-pdf\/33\/1\/45\/59832012\/riae057.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T09:41:59Z","timestamp":1738921319000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ijpp\/article\/33\/1\/45\/7821513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,14]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,10,14]]},"published-print":{"date-parts":[[2025,2,7]]}},"URL":"https:\/\/doi.org\/10.1093\/ijpp\/riae057","relation":{},"ISSN":["0961-7671","2042-7174"],"issn-type":[{"value":"0961-7671","type":"print"},{"value":"2042-7174","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,1]]},"published":{"date-parts":[[2024,10,14]]}}}