{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T13:18:53Z","timestamp":1771420733266,"version":"3.50.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To find a novel way to successfully transition patients from methadone to buprenorphine and in turn reduce the percentage of methadone prescribed within National Health Service Dumfries &amp; Galloway (NHS D&amp;G).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Three micro-dosing schedules were developed. Outcomes measured: patient numbers, success rates, prior methadone dose, Opiate Substitution Therapy following micro-dosing. A patient feedback questionnaire was developed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key findings<\/jats:title>\n                    <jats:p>177 patients micro-dosed between 06\/09\/21 and 28\/05\/24. Around 132 patients successfully transitioned from methadone to buprenorphine through micro-dosing (74.5%). Shift in prescribing: 60.5% buprenorphine\/39.5% methadone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Micro-dosing is now a standardized approach to transitioning from methadone to buprenorphine in NHS Dumfries &amp; Galloway.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ijpp\/riaf070","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T11:38:23Z","timestamp":1754480303000},"page":"88-90","source":"Crossref","is-referenced-by-count":0,"title":["A study of micro-dosing\u2014transferring from methadone to buprenorphine in NHS Dumfries &amp; Galloway"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6534-5868","authenticated-orcid":false,"given":"Samantha","family":"Nairn","sequence":"first","affiliation":[{"name":"NHS D&G, NHS Specialist Drug and Alcohol Service , 12-28 Lochfield Road, Dumfries, DG2 9BH ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Steele","sequence":"additional","affiliation":[{"name":"NHS D&G, NHS Specialist Drug and Alcohol Service , 12-28 Lochfield Road, Dumfries, DG2 9BH ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eilish","family":"Bell","sequence":"additional","affiliation":[{"name":"NHS D&G, NHS Specialist Drug and Alcohol Service , 12-28 Lochfield Road, Dumfries, DG2 9BH ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Blount","sequence":"additional","affiliation":[{"name":"NHS D&G, NHS Specialist Drug and Alcohol Service , 12-28 Lochfield Road, Dumfries, DG2 9BH ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,1]]},"reference":[{"key":"2026021807420125000_ref1","volume-title":"Analysis Reveals Families and Communities Impacted by Drug-Related Deaths in Scotland","author":"Public Health Scotland"},{"key":"2026021807420125000_ref2","volume-title":"Drug Related Deaths in Scotland in 2023","author":"National Records of Scotland"},{"key":"2026021807420125000_ref3","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.yrtph.2010.12.007","article-title":"Uniform assessment and ranking of opioid \u03bc receptor binding constants for selected opioid drugs","volume":"59","author":"Volpe","year":"2011","journal-title":"Regul Toxicol Pharmacol"},{"key":"2026021807420125000_ref4","author":"NHS Health Research Authority 2022"},{"key":"2026021807420125000_ref5","doi-asserted-by":"publisher","first-page":"99","DOI":"10.2147\/SAR.S109919","article-title":"Use of microdoses for induction of buprenorphine treatment with overlapping full opioid agonist use: the Bernese method","volume":"7","author":"H\u00e4mmig","year":"2016","journal-title":"Subst Abus Rehabil"}],"container-title":["International Journal of Pharmacy Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ijpp\/article\/doi\/10.1093\/ijpp\/riaf070\/8223132","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ijpp\/article-pdf\/34\/1\/88\/64171699\/riaf070.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ijpp\/article-pdf\/34\/1\/88\/64171699\/riaf070.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T12:42:10Z","timestamp":1771418530000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ijpp\/article\/34\/1\/88\/8223132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,1]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,9,1]]},"published-print":{"date-parts":[[2026,2,18]]}},"URL":"https:\/\/doi.org\/10.1093\/ijpp\/riaf070","relation":{},"ISSN":["0961-7671","2042-7174"],"issn-type":[{"value":"0961-7671","type":"print"},{"value":"2042-7174","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2025,9,1]]}}}