{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T23:29:17Z","timestamp":1786490957676,"version":"build-2736575974"},"reference-count":29,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post-stroke fatigue and mental health disorders are common but often overlooked. Health professionals\u2019 perspectives play a critical role in recognizing, assessing, and managing these symptoms, which significantly influence recovery and quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To explore health professionals\u2019 perspectives of post-stroke treatments and identify factors influencing treatment preferences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Vignette-based semi-structured interviews were conducted either in person or online\/by telephone with health professionals, who were asked for their perspectives on four treatment vignettes using a 5-point Likert scale. Qualitative data were analysed thematically, and quantitative data were compared using non-parametric tests. Key themes were mapped to the Bio-Psycho-Social-Systems (BPSS) model to explore factors influencing treatment preferences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key findings<\/jats:title>\n                    <jats:p>Sixteen of 20 health professionals provided numerical ratings. There were no significant differences in \u2018liking\u2019 ratings for any fatigue or mental health vignette. CBT was most frequently the most preferred option for managing fatigue (90.0%), followed by modafinil (10.0%). For mental health, nortriptyline was most frequently the most preferred treatment (37.5%), followed by herbal medicines plus fluoxetine and acupuncture (25.0% each) and repetitive transcranial magnetic stimulation (12.5%). Five influencing themes were mapped to the BPSS model: therapeutic side effects and safety concerns (biological); evidence base and perceived efficacy (biological); accessibility and system practicality (systems); patient preferences (psychological\/social); and professional scope and confidence (psychological\/systems).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Whilst health professionals were open to non-pharmacological strategies for managing post-stroke complications, conventional pharmacotherapy was preferred, either alone or in combination with other therapies, especially for severe mental health disorders.<\/jats:p>\n                  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