{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:18:43Z","timestamp":1787771923816,"version":"build-2784847793"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T00:00:00Z","timestamp":1584403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Centers for Disease Control and Prevention Emerging Infections Program Cooperative Agreement","award":["U50CK000198"],"award-info":[{"award-number":["U50CK000198"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Influenza infection causes substantial morbidity and mortality. However, little is known about hospital readmissions after an influenza hospitalization. The aim of our study was to characterize frequency of hospital readmissions among patients hospitalized with laboratory-confirmed influenza.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a retrospective study using Tennessee Emerging Infections Program Influenza Surveillance data from 2006 to 2016 and the concurrent Tennessee Hospital Discharge Data System. We analyzed demographic characteristics and outcomes to better understand frequency and factors associated with hospital readmissions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the 2897 patients with a laboratory-confirmed influenza hospitalization, 409 (14%) and 1364 (47%) had at least 1 hospital readmission within 30 days and 1 year of the influenza hospitalization, respectively. Multiple readmissions occurred in 739 patients (54%). The readmission group was older, female predominant, and had more comorbidities than patients not hospitalized. Pneumonia, acute chronic obstructive pulmonary disease\/asthma exacerbation, septicemia, acute respiratory failure, and acute renal failure were the most common causes for readmission at 30 days. Underlying cardiovascular disease, lung disease, kidney disease, diabetes, immunosuppression, and liver disease were associated with increased risk of readmission during the subsequent year.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>After an admission with laboratory-confirmed influenza, there is a high likelihood of readmission within 30 days and 1 year adding to the morbidity of influenza.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiaa117","type":"journal-article","created":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T20:22:42Z","timestamp":1584217362000},"page":"583-589","source":"Crossref","is-referenced-by-count":17,"title":["Hospital Readmissions After Laboratory-Confirmed Influenza Hospitalization"],"prefix":"10.1093","volume":"222","author":[{"suffix":"Jr.","given":"David M","family":"Dobrzynski","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle N","family":"Ndi","sequence":"additional","affiliation":[{"name":"Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffanie","family":"Markus","sequence":"additional","affiliation":[{"name":"Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Schaffner","sequence":"additional","affiliation":[{"name":"Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA"},{"name":"Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H Keipp","family":"Talbot","sequence":"additional","affiliation":[{"name":"Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA"},{"name":"Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,3,17]]},"reference":[{"key":"2020072311064825000_CIT0001","author":"Centers for Disease Control and Prevention. Disease Burden of Influenza"},{"key":"2020072311064825000_CIT0002","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1136\/heartjnl-2015-307691","article-title":"Acute myocardial infarction and influenza: a meta-analysis of case-control studies","volume":"101","author":"Barnes","year":"2015","journal-title":"Heart"},{"key":"2020072311064825000_CIT0003","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1093\/infdis\/jir175","article-title":"Influenza and acute myocardial infarction","volume":"203","author":"Finelli","year":"2011","journal-title":"J Infect Dis"},{"key":"2020072311064825000_CIT0004","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1017\/S0950268812002890","article-title":"Acute myocardial infarctions, strokes and influenza: seasonal and pandemic effects","volume":"141","author":"Foster","year":"2013","journal-title":"Epidemiol Infect"},{"key":"2020072311064825000_CIT0005","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1007\/s10753-008-9074-2","article-title":"Influenza virus infection and risk of acute myocardial infarction","volume":"31","author":"Guan","year":"2008","journal-title":"Inflammation"},{"key":"2020072311064825000_CIT0006","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s12872-015-0095-0","article-title":"Acute cardiac injury events \u226430 days after laboratory-confirmed influenza virus infection among U.S. veterans, 2010-2012","volume":"15","author":"Ludwig","year":"2015","journal-title":"BMC Cardiovasc Disord"},{"key":"2020072311064825000_CIT0007","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1001\/jamacardio.2016.0433","article-title":"Seasonal influenza infections and cardiovascular disease mortality","volume":"1","author":"Nguyen","year":"2016","journal-title":"JAMA Cardiol"},{"key":"2020072311064825000_CIT0008","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1093\/infdis\/jis597","article-title":"Influenza infection and risk of acute myocardial infarction in England and Wales: a CALIBER self-controlled case series study","volume":"206","author":"Warren-Gash","year":"2012","journal-title":"J Infect Dis"},{"key":"2020072311064825000_CIT0009","first-page":"53257","article-title":"Medicare program; hospital inpatient prospective payment systems for acute care hospitals and the long-term care hospital prospective payment system and fiscal year 2013 rates; hospitals\u2019 resident caps for graduate medical education payment purposes; quality reporting requirements for specific providers and for ambulatory surgical centers. Final Rule","volume":"77","author":"Centers for Medicare and Medicaid Services (CMS), HHS","year":"2012","journal-title":"Fed Regist"},{"key":"2020072311064825000_CIT0010","doi-asserted-by":"crossref","first-page":"e20160938","DOI":"10.1542\/peds.2016-0938","article-title":"Pediatric readmissions after hospitalizations for lower respiratory infections","volume":"140","author":"Nakamura","year":"2017","journal-title":"Pediatrics"},{"key":"2020072311064825000_CIT0011","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1542\/hpeds.2014-0045","article-title":"Hospital readmissions among children with H1N1 influenza infection","volume":"4","author":"Brogan","year":"2014","journal-title":"Hosp Pediatr"},{"key":"2020072311064825000_CIT0012","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.2307\/4580606","article-title":"Excess mortality from cause other than influenza and pneumonia during influenza epidemics","volume":"47","author":"Collins","year":"1932","journal-title":"Pub Health Rep"},{"key":"2020072311064825000_CIT0013","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1056\/NEJMoa1702090","article-title":"Acute myocardial infarction after laboratory-confirmed influenza infection","volume":"378","author":"Kwong","year":"2018","journal-title":"N Engl J Med"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jid\/advance-article-pdf\/doi\/10.1093\/infdis\/jiaa117\/33033334\/jiaa117.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/222\/4\/583\/33524552\/jiaa117.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/222\/4\/583\/33524552\/jiaa117.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T15:08:33Z","timestamp":1595516913000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/222\/4\/583\/5808013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,17]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,3,17]]},"published-print":{"date-parts":[[2020,7,23]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jiaa117","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"value":"0022-1899","type":"print"},{"value":"1537-6613","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,8,15]]},"published":{"date-parts":[[2020,3,17]]}}}