{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:04:40Z","timestamp":1792652680932,"version":"4.5.0"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"Supplement_3","license":[{"start":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T00:00:00Z","timestamp":1608076800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This review will consider the gut as a reservoir for antimicrobial resistance, colonization resistance, and how disruption of the microbiome can lead to colonization by pathogenic organisms. There is a focus on the gut as a reservoir for \u03b2-lactam and plasmid-mediated quinolone resistance. Finally, the role of functional metagenomics and long-read sequencing technologies to detect and understand antimicrobial resistance genes within the gut microbiome is discussed, along with the potential for future microbiome-directed methods to detect and prevent infection.<\/jats:p>","DOI":"10.1093\/infdis\/jiaa497","type":"journal-article","created":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T00:48:57Z","timestamp":1597711737000},"page":"S209-S213","source":"Crossref","is-referenced-by-count":170,"title":["The Gut Microbiome as a Reservoir for Antimicrobial Resistance"],"prefix":"10.1093","volume":"223","author":[{"given":"Winston E","family":"Anthony","sequence":"first","affiliation":[{"name":"The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carey-Ann D","family":"Burnham","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"},{"name":"Department of Medicine, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"},{"name":"Department of Pediatrics, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"},{"name":"Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0455-8370","authenticated-orcid":false,"given":"Gautam","family":"Dantas","sequence":"additional","affiliation":[{"name":"The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"},{"name":"Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"},{"name":"Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"},{"name":"Department of Biomedical Engineering, Washington University in St. Louis, St Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7824-6276","authenticated-orcid":false,"given":"Jennie H","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Medicine, Washington University School of Medicine in St. Louis, St Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,12,16]]},"reference":[{"key":"2021061607042939200_CIT0001","first-page":"277","article-title":"The antibiotic resistance crisis. 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