{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T09:05:27Z","timestamp":1740128727342,"version":"3.37.3"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T00:00:00Z","timestamp":1605139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100011072","name":"University of North Carolina at Chapel Hill Center for AIDS Research","doi-asserted-by":"crossref","award":["P30 AI050410"],"award-info":[{"award-number":["P30 AI050410"]}],"id":[{"id":"10.13039\/100011072","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We conducted a prospective study of 13 heterosexual couples to understand the impact of recent condomless vaginal sex on vaginal immune marker measurement and potential exposure misclassification due to the presence of semen. All immune markers were detectable in semen and concentrations of vaginal immune markers varied by sex recency.<\/jats:p>","DOI":"10.1093\/infdis\/jiaa705","type":"journal-article","created":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T20:11:48Z","timestamp":1604693508000},"page":"137-140","source":"Crossref","is-referenced-by-count":3,"title":["What\u2019s Sex Got to Do With It? Understanding Potential Confounding and Exposure Misclassification in Mechanistic Sexually Transmitted Infection Research"],"prefix":"10.1093","volume":"224","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1535-1076","authenticated-orcid":false,"given":"Jennifer","family":"Deese","sequence":"first","affiliation":[{"name":"Global Public Health Impact Center, RTI International, Research Triangle Park, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Wang","sequence":"additional","affiliation":[{"name":"Target PharmaSolutions, Durham, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Lapple","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie A E","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bethany","family":"Kuerten","sequence":"additional","affiliation":[{"name":"Upstream USA, Raleigh, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus J","family":"Steiner","sequence":"additional","affiliation":[{"name":"Product Development and Introduction, FHI 360, Durham, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pai Lien","family":"Chen","sequence":"additional","affiliation":[{"name":"Biostatistics, FHI 360, Durham, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcia M","family":"Hobbs","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,11,12]]},"reference":[{"key":"2021090910511935900_CIT0001","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1093\/infdis\/jis555","article-title":"Mucosal Escherichia coli bactericidal activity and immune mediators are associated with HIV-1 seroconversion in women participating in the HPTN 035 trial","volume":"206","author":"Dezzutti","year":"2012","journal-title":"J Infect Dis"},{"key":"2021090910511935900_CIT0002","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1097\/QAD.0b013e3283367836","article-title":"Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression","volume":"24","author":"Roberts","year":"2010","journal-title":"AIDS"},{"key":"2021090910511935900_CIT0003","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/QAI.0000000000000103","article-title":"Cervical inflammation and immunity associated with hormonal contraception, pregnancy, and HIV-1 seroconversion","volume":"66","author":"Morrison","year":"2014","journal-title":"J Acquir Immune Defic Syndr"},{"key":"2021090910511935900_CIT0004","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1056\/NEJMoa1108524","article-title":"Antiretroviral prophylaxis for HIV prevention in heterosexual men and women","volume":"367","author":"Baeten","year":"2012","journal-title":"N Engl J Med"},{"key":"2021090910511935900_CIT0005","article-title":"Genital cytokine elevation is associated with HIV infection","volume-title":"HIV Research for Prevention","author":"Deese","year":"2017"},{"key":"2021090910511935900_CIT0006","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00441-005-1127-3","article-title":"Seminal plasma and male factor signalling in the female reproductive tract","volume":"322","author":"Robertson","year":"2005","journal-title":"Cell Tissue Res"},{"key":"2021090910511935900_CIT0007","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1152\/physrev.00013.2018","article-title":"The female response to seminal fluid","volume":"100","author":"Schjenken","year":"2020","journal-title":"Physiol Rev"},{"key":"2021090910511935900_CIT0008","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1093\/biolre\/ioy071","article-title":"Interferon-gamma inhibits seminal plasma induction of colony-stimulating factor 2 in mouse and human reproductive tract epithelial cells","volume":"99","author":"Sharkey","year":"2018","journal-title":"Biol Reprod"},{"key":"2021090910511935900_CIT0009","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.4049\/jimmunol.1200005","article-title":"TGF-\u03b2 mediates proinflammatory seminal fluid signaling in human cervical epithelial cells","volume":"189","author":"Sharkey","year":"2012","journal-title":"J Immunol"},{"key":"2021090910511935900_CIT0010","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1093\/molehr\/5.3.220","article-title":"Seminal plasma components stimulate interleukin-8 and interleukin-10 release","volume":"5","author":"Denison","year":"1999","journal-title":"Mol Hum Reprod"},{"key":"2021090910511935900_CIT0011","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/aji.12415","article-title":"Injectable progestin-only contraception is associated with increased levels of pro-inflammatory cytokines in the female genital tract","volume":"74","author":"Deese","year":"2015","journal-title":"Am J Reprod Immunol"},{"key":"2021090910511935900_CIT0012","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1258\/095646207779949899","article-title":"Validity of self-reported \u2018safe sex\u2019 among female sex workers in Mombasa, Kenya\u2013PSA analysis","volume":"18","author":"Gallo","year":"2007","journal-title":"Int J STD AIDS"},{"key":"2021090910511935900_CIT0013","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0010-7824(99)00013-X","article-title":"Prostate-specific antigen in vaginal fluid as a biologic marker of condom failure","volume":"59","author":"Macaluso","year":"1999","journal-title":"Contraception"},{"key":"2021090910511935900_CIT0014","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1097\/OLQ.0b013e3181a2b4bf","article-title":"Good performance of rapid prostate-specific antigen test for detection of semen exposure in women: implications for qualitative research","volume":"36","author":"Hobbs","year":"2009","journal-title":"Sex Transm Dis"},{"key":"2021090910511935900_CIT0015","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1093\/cid\/civ298","article-title":"Genital inflammation and the risk of HIV acquisition in women","volume":"61","author":"Masson","year":"2015","journal-title":"Clin Infect Dis"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jid\/advance-article-pdf\/doi\/10.1093\/infdis\/jiaa705\/35073642\/jiaa705.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/224\/1\/137\/40336060\/jiaa705.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/224\/1\/137\/40336060\/jiaa705.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T10:57:45Z","timestamp":1631185065000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/224\/1\/137\/5974974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,12]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,11,12]]},"published-print":{"date-parts":[[2021,7,2]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jiaa705","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"type":"print","value":"0022-1899"},{"type":"electronic","value":"1537-6613"}],"subject":[],"published-other":{"date-parts":[[2021,7,1]]},"published":{"date-parts":[[2020,11,12]]}}}