{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:29:08Z","timestamp":1793197748789,"version":"4.5.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T00:00:00Z","timestamp":1606521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004257","name":"Helse Vest","doi-asserted-by":"publisher","award":["F-11628"],"award-info":[{"award-number":["F-11628"]}],"id":[{"id":"10.13039\/501100004257","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016190","name":"Trond Mohn Foundation","doi-asserted-by":"publisher","award":["TMS2020TMT05"],"award-info":[{"award-number":["TMS2020TMT05"]}],"id":[{"id":"10.13039\/100016190","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003506","name":"Ministry of Health and Care Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003506","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Norwegian Research Council Globvac","award":["284930"],"award-info":[{"award-number":["284930"]}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","award":["EU IMI115672"],"award-info":[{"award-number":["EU IMI115672"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","award":["H2020 874866"],"award-info":[{"award-number":["H2020 874866"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005036","name":"University of Bergen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005036","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Nanomedicines Flunanoair","award":["JTC2016"],"award-info":[{"award-number":["JTC2016"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>During the coronavirus disease 2019 (COVID-19) pandemic, many countries experienced infection in health care workers (HCW) due to overburdened health care systems. Whether infected HCW acquire protective immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a Norwegian prospective cohort study, we enrolled 607 HCW before and after the first COVID-19 wave. Exposure history, COVID-19\u2013like symptoms, and serum samples were collected. SARS-CoV-2\u2013specific antibodies were characterized by spike-protein IgG\/IgM\/IgA enzyme-linked immunosorbent and live-virus neutralization assays.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Spike-specific IgG\/IgM\/IgA antibodies increased after the first wave in HCW with, but not in HCW without, COVID-19 patient exposure. Thirty-two HCW (5.3%) had spike-specific antibodies (11 seroconverted with \u22654-fold increase, 21 were seropositive at baseline). Neutralizing antibodies were found in 11 HCW that seroconverted, of whom 4 (36.4%) were asymptomatic. Ninety-seven HCW were tested by reverse transcriptase polymerase chain reaction (RT-PCR) during follow-up; 8 were positive (7 seroconverted, 1 had undetectable antibodies).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We found increases in SARS-CoV-2 neutralizing antibodies in infected HCW, especially after COVID-19 patient exposure. Our data show a low number of SARS-CoV-2\u2013seropositive HCW in a low-prevalence setting; however, the proportion of seropositivity was higher than RT-PCR positivity, highlighting the importance of antibody testing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/infdis\/jiaa737","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T07:21:35Z","timestamp":1606288895000},"page":"589-599","source":"Crossref","is-referenced-by-count":46,"title":["SARS-CoV-2\u2013Specific Neutralizing Antibody Responses in Norwegian Health Care Workers After the First Wave of COVID-19 Pandemic: A Prospective Cohort Study"],"prefix":"10.1093","volume":"223","author":[{"given":"Mai-Chi","family":"Trieu","sequence":"first","affiliation":[{"name":"Department of Clinical Science, Influenza Centre, University of Bergen, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, Influenza Centre, University of Bergen, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Madsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, Influenza Centre, University of Bergen, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, Influenza Centre, University of Bergen, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"S\u00e6vik","sequence":"additional","affiliation":[{"name":"Department of Medicine, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha","family":"Vahokoski","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, Influenza Centre, University of Bergen, Bergen, Norway"},{"name":"Department of Medicine, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl Albert","family":"Brokstad","sequence":"additional","affiliation":[{"name":"Broeglemann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway"},{"name":"Department of Safety, Chemistry and Biomedical Laboratory Sciences, Western Norway University of Applied Sciences, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4121-776X","authenticated-orcid":false,"given":"Florian","family":"Krammer","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"T\u00f8ndel","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin G I","family":"Mohn","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, Influenza Centre, University of Bergen, Bergen, Norway"},{"name":"Emergency Care Clinic, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f8rn","family":"Blomberg","sequence":"additional","affiliation":[{"name":"Department of Medicine, Haukeland University Hospital, Bergen, Norway"},{"name":"Department of Clinical Science, University of Bergen, Bergen, Norway"},{"name":"National Centre for Tropical Infectious Diseases, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Langeland","sequence":"additional","affiliation":[{"name":"Department of Medicine, Haukeland University Hospital, Bergen, Norway"},{"name":"Department of Clinical Science, University of Bergen, Bergen, Norway"},{"name":"National Centre for Tropical Infectious Diseases, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca J","family":"Cox","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, Influenza Centre, University of Bergen, Bergen, Norway"},{"name":"Department of Microbiology, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Bergen COVID-19 Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e5rd","family":"Kittang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagrunn Waag","family":"Linchausen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5kon","family":"Amdam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese Bredholt","family":"Onyango","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geir","family":"Bredholt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Ertesv\u00e5g","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Lartey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helene Heitmann","family":"Sandnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrik","family":"Gr\u00f8van","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hauke","family":"Bartsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Syre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Real","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5se Garl\u00f8v","family":"Berg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,28]]},"reference":[{"key":"2021022419590590400_CIT0001","author":"World Health Organization"},{"key":"2021022419590590400_CIT0002","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1001\/jama.2020.4344","article-title":"Coronavirus disease 2019 (COVID-19) in Italy","volume":"323","author":"Livingston","year":"2020","journal-title":"JAMA"},{"key":"2021022419590590400_CIT0003","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/S0140-6736(20)30627-9","article-title":"COVID-19 and Italy: what next?","volume":"395","author":"Remuzzi","year":"2020","journal-title":"Lancet"},{"key":"2021022419590590400_CIT0004","doi-asserted-by":"crossref","first-page":"e209666","DOI":"10.1001\/jamanetworkopen.2020.9666","article-title":"Coronavirus disease 2019 (COVID-2019) infection among health care workers and implications for prevention measures in a tertiary hospital in Wuhan, China","volume":"3","author":"Lai","year":"2020","journal-title":"JAMA Netw Open"},{"key":"2021022419590590400_CIT0005","doi-asserted-by":"crossref","first-page":"e475","DOI":"10.1016\/S2468-2667(20)30164-X","article-title":"Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study","volume":"5","author":"Nguyen","year":"2020","journal-title":"Lancet Public Health"},{"key":"2021022419590590400_CIT0006","doi-asserted-by":"crossref","first-page":"104437","DOI":"10.1016\/j.jcv.2020.104437","article-title":"SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients","volume":"128","author":"Korth","year":"2020","journal-title":"J Clin Virol"},{"key":"2021022419590590400_CIT0007","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1038\/s41467-020-17318-x","article-title":"Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital","volume":"11","author":"Garcia-Basteiro","year":"2020","journal-title":"Nat Commun"},{"key":"2021022419590590400_CIT0008","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1007\/s11606-020-05926-8","article-title":"Prevalence of SARS-CoV-2 antibodies among healthcare workers at a tertiary academic hospital in New York City","volume":"35","author":"Mansour","year":"2020","journal-title":"J Gen Intern Med"},{"key":"2021022419590590400_CIT0009","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1001\/jama.2020.11160","article-title":"Hospital-wide SARS-CoV-2 antibody screening in 3056 staff in a tertiary center in Belgium","volume":"324","author":"Steensels","year":"2020","journal-title":"JAMA"},{"key":"2021022419590590400_CIT0010","article-title":"Exclusive: deaths of NHS staff from COVID-19 analysed","author":"Cook","year":"22","journal-title":"Health Service Journal"},{"key":"2021022419590590400_CIT0011","doi-asserted-by":"crossref","first-page":"e0233255","DOI":"10.1371\/journal.pone.0233255","article-title":"Geo-temporal distribution of 1,688 Chinese healthcare workers infected with COVID-19 in severe conditions-a secondary data analysis","volume":"15","author":"Gao","year":"2020","journal-title":"PLoS One"},{"key":"2021022419590590400_CIT0012","author":"The Guardian"},{"key":"2021022419590590400_CIT0013","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jinf.2020.05.067","article-title":"High SARS-CoV-2 antibody prevalence among healthcare workers exposed to COVID-19 patients","volume":"81","author":"Chen","year":"2020","journal-title":"J Infect"},{"key":"2021022419590590400_CIT0014","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1038\/s41591-020-0913-5","article-title":"A serological assay to detect SARS-CoV-2 seroconversion in humans","volume":"26","author":"Amanat","year":"2020","journal-title":"Nat Med"},{"key":"2021022419590590400_CIT0015","author":"Folkehelseinstituttet"},{"key":"2021022419590590400_CIT0016","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2013a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"key":"2021022419590590400_CIT0017","doi-asserted-by":"crossref","article-title":"Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with high attack rate.","author":"Addetia","DOI":"10.1128\/JCM.02107-20"},{"key":"2021022419590590400_CIT0018","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1126\/science.abc5343","article-title":"Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques","volume":"369","author":"Deng","year":"2020","journal-title":"Science"},{"key":"2021022419590590400_CIT0019","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1056\/NEJMoa2024671","article-title":"Evaluation of the mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates","volume":"383","author":"Corbett","year":"2020","journal-title":"N Engl J Med"},{"key":"2021022419590590400_CIT0020","doi-asserted-by":"crossref","first-page":"e209673","DOI":"10.1001\/jamanetworkopen.2020.9673","article-title":"Prevalence and clinical presentation of health care workers with symptoms of coronavirus disease 2019 in 2 Dutch hospitals during an early phase of the pandemic","volume":"3","author":"Kluytmans-van den Bergh","year":"2020","journal-title":"JAMA Netw Open"},{"key":"2021022419590590400_CIT0021","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1016\/S0140-6736(20)31484-7","article-title":"Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers","volume":"396","author":"Houlihan","year":"2020","journal-title":"Lancet"},{"key":"2021022419590590400_CIT0022","article-title":"SARS-CoV-2 infection among healthcare workers in a hospital in Madrid, Spain","author":"Su\u00e1rez-Garc\u00eda","journal-title":"J Hosp Infect 2020; 106:357\u201363"},{"key":"2021022419590590400_CIT0023","doi-asserted-by":"crossref","first-page":"2000433","DOI":"10.2807\/1560-7917.ES.2020.25.14.2000433","article-title":"Roll-out of SARS-CoV-2 testing for healthcare workers at a large NHS foundation trust in the United Kingdom, March 2020","volume":"25","author":"Keeley","year":"2020","journal-title":"Euro Surveill"},{"key":"2021022419590590400_CIT0024","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/s41586-020-2405-7","article-title":"Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe","volume":"584","author":"Flaxman","year":"2020","journal-title":"Nature"},{"key":"2021022419590590400_CIT0025","doi-asserted-by":"crossref","first-page":"262\u20137","DOI":"10.1038\/s41586-020-2404-8","article-title":"The effect of large-scale anti-contagion policies on the COVID-19 pandemic","volume":"584","author":"Hsiang","year":"2020","journal-title":"Nature"},{"key":"2021022419590590400_CIT0026","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1001\/jama.2020.14765","article-title":"Prevalence of SARS-CoV-2 antibodies in health care personnel in the New York City area","volume":"324","author":"Moscola","year":"2020","journal-title":"JAMA"},{"key":"2021022419590590400_CIT0027","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1093\/cid\/ciaa287","article-title":"Risk factors of healthcare workers with corona virus disease 2019: a retrospective cohort study in a designated hospital of Wuhan in China","volume":"71","author":"Ran","year":"2020","journal-title":"Clin Infect Dis"},{"key":"2021022419590590400_CIT0028","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0140-6736(20)31483-5","article-title":"Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study","volume":"396","author":"Poll\u00e1n","year":"2020","journal-title":"Lancet"},{"key":"2021022419590590400_CIT0029","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.cell.2020.08.017","article-title":"Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19","volume":"183","author":"Sekine","year":"2020","journal-title":"Cell"},{"key":"2021022419590590400_CIT0030","article-title":"Clinical course and molecular viral shedding among asymptomatic and symptomatic patients with SARS-CoV-2 infection in a community treatment center in the Republic of Korea","author":"Lee","journal-title":"JAMA Intern Med"},{"key":"2021022419590590400_CIT0031","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.3201\/eid2611.203219","article-title":"SARS-CoV-2 virus culture and subgenomic RNA for respiratory specimens from patients with mild coronavirus disease","volume":"26","author":"Perera","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"2021022419590590400_CIT0032","first-page":"922","article-title":"COVID-19: protecting health-care workers","volume":"395","author":"The Lancet","year":"2020","journal-title":"Lancet"},{"key":"2021022419590590400_CIT0033","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.1016\/S2213-2600(20)30406-9","article-title":"Serological assays for delayed SARS-CoV-2 case identification\u2014author\u2019s reply","volume":"8","author":"Pallett","year":"2020","journal-title":"Lancet Respir Med"},{"key":"2021022419590590400_CIT0034","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1016\/S0140-6736(20)30970-3","article-title":"First experience of COVID-19 screening of health-care workers in England","volume":"395","author":"Hunter","year":"2020","journal-title":"Lancet"},{"key":"2021022419590590400_CIT0035","doi-asserted-by":"crossref","first-page":"e58728","DOI":"10.7554\/eLife.58728","article-title":"Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission","volume":"9","author":"Rivett","year":"2020","journal-title":"Elife"},{"key":"2021022419590590400_CIT0036","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jhin.2020.06.028","article-title":"Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff","volume":"106","author":"Martin","year":"2020","journal-title":"J Hosp Infect"},{"key":"2021022419590590400_CIT0037","article-title":"Antibodies against SARS-CoV-2 among health care workers in a country with low burden of COVID-19","author":"Psichogiou","journal-title":"PLOS ONE 2020;15:e0243025"},{"key":"2021022419590590400_CIT0038","doi-asserted-by":"crossref","first-page":"459","DOI":"10.4103\/ijmr.IJMR_2234_20","article-title":"Healthcare workers and SARS-CoV-2 infection in India: a case-control investigation in the time of COVID-19","volume":"151","author":"Chatterjee","year":"2020","journal-title":"Indian J Med Res"},{"key":"2021022419590590400_CIT0039","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/S1473-3099(20)30589-2","article-title":"Risk of COVID-19 in health-care workers in Denmark: an observational cohort study","volume":"20","author":"Iversen","year":"2020","journal-title":"Lancet Infect Dis"},{"key":"2021022419590590400_CIT0040","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S1473-3099(20)30527-2","article-title":"COVID-19 in health-care workers in three hospitals in the south of the Netherlands: a cross-sectional study","volume":"20","author":"Sikkema","year":"2020","journal-title":"Lancet Infect Dis"},{"key":"2021022419590590400_CIT0041","article-title":"Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donors","author":"Zeng","journal-title":"JCI Insight 2020; 5:e143213"},{"key":"2021022419590590400_CIT0042","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.cell.2020.06.043","article-title":"Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus","volume":"182","author":"Korber","year":"2020","journal-title":"Cell"},{"key":"2021022419590590400_CIT0043","article-title":"COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing","author":"To","journal-title":"Clin Infect Dis"},{"key":"2021022419590590400_CIT0044","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1126\/science.abc6284","article-title":"DNA vaccine protection against SARS-CoV-2 in rhesus macaques","volume":"369","author":"Yu","year":"2020","journal-title":"Science"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jid\/advance-article-pdf\/doi\/10.1093\/infdis\/jiaa737\/35203801\/jiaa737.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/223\/4\/589\/36355855\/jiaa737.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/223\/4\/589\/36355855\/jiaa737.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T02:43:03Z","timestamp":1618454583000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/223\/4\/589\/6009023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,28]]},"references-count":44,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,11,28]]},"published-print":{"date-parts":[[2021,2,24]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jiaa737","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"value":"0022-1899","type":"print"},{"value":"1537-6613","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,2,15]]},"published":{"date-parts":[[2020,11,28]]}}}