{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:50:49Z","timestamp":1788691849278,"version":"build-2803163510"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T00:00:00Z","timestamp":1611705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Published data regarding long-lasting immunological rabies memory after pre-exposure prophylaxis (PrEP) are scarce. We tested the hypothesis that rabies booster immunization elicits rapid anamnestic responses.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>For this observational study, we included participants who had received PrEP 10\u201324 years before inclusion. We measured rabies antibody titers before, and on days 3, 7, and 14 after a single intramuscular booster.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>All 28 participants responded adequately regardless of route of administration or 2-dose vs 3-dose PrEP regimen.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Rabies immunological memory is reactivated within 7 days after a single intramuscular booster immunization, even when administered 10\u201324 years after PrEP.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiab034","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T20:13:04Z","timestamp":1611087184000},"page":"1052-1056","source":"Crossref","is-referenced-by-count":16,"title":["Long-term Memory Response After a Single Intramuscular Rabies Booster Vaccination 10\u201324 Years After Primary Immunization"],"prefix":"10.1093","volume":"226","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5036-4724","authenticated-orcid":false,"given":"Cornelis A","family":"De Pijper","sequence":"first","affiliation":[{"name":"Amsterdam University Medical Centers, University of Amsterdam, Division of Internal Medicine, Department of Infectious Diseases, Center for Tropical Medicine and Travel Medicine, Amsterdam Infection and Immunity, Amsterdam Public Health , Amsterdam , Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annefleur C","family":"Langedijk","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers, University of Amsterdam, Division of Internal Medicine, Department of Infectious Diseases, Center for Tropical Medicine and Travel Medicine, Amsterdam Infection and Immunity, Amsterdam Public Health , Amsterdam , Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanne","family":"Terryn","sequence":"additional","affiliation":[{"name":"National Reference Center of Rabies, Viral Diseases, Infectious Diseases in Humans, Sciensano , Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Van Gucht","sequence":"additional","affiliation":[{"name":"National Reference Center of Rabies, Viral Diseases, Infectious Diseases in Humans, Sciensano , Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin P","family":"Grobusch","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers, University of Amsterdam, Division of Internal Medicine, Department of Infectious Diseases, Center for Tropical Medicine and Travel Medicine, Amsterdam Infection and Immunity, Amsterdam Public Health , Amsterdam , Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Goorhuis","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers, University of Amsterdam, Division of Internal Medicine, Department of Infectious Diseases, Center for Tropical Medicine and Travel Medicine, Amsterdam Infection and Immunity, Amsterdam Public Health , Amsterdam , Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelis","family":"Stijnis","sequence":"additional","affiliation":[{"name":"Amsterdam University Medical Centers, University of Amsterdam, Division of Internal Medicine, Department of Infectious Diseases, Center for Tropical Medicine and Travel Medicine, Amsterdam Infection and Immunity, Amsterdam Public Health , Amsterdam , Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,1,27]]},"reference":[{"key":"2022092122005883400_CIT0001","doi-asserted-by":"crossref","first-page":"5500","DOI":"10.1016\/j.vaccine.2018.06.061","article-title":"Rabies vaccines: WHO position paper, April 2018\u2014recommendations","volume":"36","author":"World Health Organization","year":"2018","journal-title":"Vaccine"},{"key":"2022092122005883400_CIT0002","volume-title":"WHO expert consultation on rabies third report","author":"World Health Organization (WHO)","year":"2018"},{"key":"2022092122005883400_CIT0003","doi-asserted-by":"crossref","first-page":"17091","DOI":"10.1038\/nrdp.2017.91","article-title":"Rabies","volume":"3","author":"Fooks","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"2022092122005883400_CIT0004","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/nri3802","article-title":"Memory B 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