{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:40:29Z","timestamp":1789206029967,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U48 DP005013-02S7"],"award-info":[{"award-number":["U48 DP005013-02S7"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>In the United States, human papillomavirus (HPV) vaccination has been recommended since 2011 for boys aged 11\u201312 years, with catch-up vaccination recommended through age 26 years for previously unvaccinated men who have sex with men (MSM).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>During 2016\u20132018, a cross-sectional study enrolled MSM and transgender women aged 18\u201326 years in Seattle, Washington. Participants submitted self-collected penile swab specimens for HPV genotyping. HPV vaccination history was self-reported. We compared HPV prevalence among vaccinated participants with that in participants with no or unknown vaccination history, using log-binomial regression to estimate adjusted prevalence ratios and confidence intervals.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among 687 participants, 348 (50.7%) self-reported ever receiving \u22651 HPV vaccine dose; the median age at first HPV vaccination was 21 years, and the median age at first sex, 17 years. Overall, the prevalence of penile quadrivalent HPV vaccine (4vHPV)\u2013type HPV was similar in vaccinated participants (12.1%) and participants with no or unknown vaccination (15.6%) (adjusted prevalence ratio, 0.69 [95% confidence interval, .47\u20131.01]). However, the prevalence was significantly lower in participants vaccinated at age \u226418 years than in those with no of unknown vaccination (0.15 [.04\u2013.62]), corresponding to a vaccine effectiveness of 85% against 4vHPV-type HPV.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Results suggest that HPV vaccination is effective in preventing penile HPV infections in young MSM when administered at age \u226418 years.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiab390","type":"journal-article","created":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T03:13:32Z","timestamp":1627355612000},"page":"422-430","source":"Crossref","is-referenced-by-count":28,"title":["Effectiveness of Human Papillomavirus (HPV) Vaccination Against Penile HPV Infection in Men Who Have Sex With Men and Transgender Women"],"prefix":"10.1093","volume":"225","author":[{"given":"Rachel L","family":"Winer","sequence":"first","affiliation":[{"name":"Department of Epidemiology, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Troy D","family":"Querec","sequence":"additional","affiliation":[{"name":"Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth R","family":"Unger","sequence":"additional","affiliation":[{"name":"Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua E","family":"Stern","sequence":"additional","affiliation":[{"name":"Department of Global Health, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica M","family":"Rudd","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R","family":"Golden","sequence":"additional","affiliation":[{"name":"Center for AIDS & STD, University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Swanson","sequence":"additional","affiliation":[{"name":"Gay City Health Project, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauri E","family":"Markowitz","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0077-2591","authenticated-orcid":false,"given":"Elissa","family":"Meites","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"key":"2022020201044639700_CIT0001","first-page":"1","article-title":"Biological agents. 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A review of human carcinogens","volume":"100","author":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.","year":"2012","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"2022020201044639700_CIT0002","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/infdis\/jiq021","article-title":"Age-specific prevalence of and risk factors for anal human papillomavirus (HPV) among men who have sex with women and men who have sex with men: the HPV in Men (HIM) study","volume":"203","author":"Nyitray","year":"2011","journal-title":"J Infect Dis"},{"key":"2022020201044639700_CIT0003","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1093\/infdis\/jiy556","article-title":"Type-specific anal human papillomavirus prevalence among men, according to sexual preference and HIV status: a systematic literature review and meta-analysis","volume":"219","author":"Marra","year":"2019","journal-title":"J Infect 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males","volume":"364","author":"Giuliano","year":"2011","journal-title":"N Engl J Med"},{"key":"2022020201044639700_CIT0010","author":"US Food and Drug Administration.","year":"2020"},{"key":"2022020201044639700_CIT0011","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.15585\/mmwr.mm6549a5","article-title":"Use of a 2-dose schedule for human papillomavirus vaccination\u2014updated recommendations of the Advisory Committee on Immunization Practices","volume":"65","author":"Meites","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2022020201044639700_CIT0012","first-page":"1","article-title":"Human papillomavirus vaccination: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"63","author":"Markowitz","year":"2014","journal-title":"MMWR Recomm Rep"},{"key":"2022020201044639700_CIT0013","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.15585\/mmwr.mm6933a1","article-title":"National, regional, state, and selected local 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