{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:27:24Z","timestamp":1791390444885,"version":"4.3.3"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AI089674"],"award-info":[{"award-number":["AI089674"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AI075045"],"award-info":[{"award-number":["AI075045"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"crossref","award":["INDIE OPP1173572"],"award-info":[{"award-number":["INDIE OPP1173572"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"crossref","award":["OPP1169785"],"award-info":[{"award-number":["OPP1169785"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"crossref"}]},{"name":"European Research Council","award":["ERC-CoG 864180"],"award-info":[{"award-number":["ERC-CoG 864180"]}]},{"DOI":"10.13039\/100000061","name":"Fogarty International Center","doi-asserted-by":"crossref","award":["P0529898"],"award-info":[{"award-number":["P0529898"]}],"id":[{"id":"10.13039\/100000061","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000061","name":"Fogarty International Center","doi-asserted-by":"crossref","award":["TW009343"],"award-info":[{"award-number":["TW009343"]}],"id":[{"id":"10.13039\/100000061","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100001949","name":"American Society of Tropical Medicine and Hygiene","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001949","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Achieving malaria elimination requires a better understanding of the transmissibility of human infections in different transmission settings. This study aimed to characterize the human infectious reservoir in a high endemicity setting in eastern Uganda, using gametocyte quantification and mosquito feeding assays. In asymptomatic infections, gametocyte densities were positively associated with the proportion of infected mosquitoes (\u03b2\u2009=\u20091.60; 95% CI, 1.32\u20131.92; P\u2009&amp;lt;\u2009.0001). Combining transmissibility and abundance in the population, symptomatic and asymptomatic infections were estimated to contribute to 5.3% and 94.7% of the infectious reservoir, respectively. School-aged children (5\u201315 years old) contributed to 50.4% of transmission events and were important drivers of malaria transmission.<\/jats:p>","DOI":"10.1093\/infdis\/jiac169","type":"journal-article","created":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T15:11:19Z","timestamp":1651849879000},"page":"708-713","source":"Crossref","is-referenced-by-count":72,"title":["Asymptomatic School-Aged Children Are Important Drivers of Malaria Transmission in a High Endemicity Setting in Uganda"],"prefix":"10.1093","volume":"226","author":[{"given":"John","family":"Rek","sequence":"first","affiliation":[{"name":"Infectious Diseases Research Collaboration , Kampala , Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Lynn","family":"Blanken","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Radboud University Nijmegen Medical Centre , Nijmegen , The 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