{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:12:34Z","timestamp":1790244754645,"version":"4.1.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"European Research Council"},{"DOI":"10.13039\/100000865","name":"Bill & Melinda Gates Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Chikungunya virus (CHIKV) is a major public health concern worldwide. However, infection levels are rarely known, especially in Africa. We recruited individuals from Ouagadougou, Burkina Faso and Lambar\u00e9n\u00e9, Gabon (age range, 1\u201355 years), tested their blood for CHIKV antibodies, and used serocatalytic models to reconstruct epidemiological histories. In Ouagadougou, 291 of 999 (29.1%) individuals were seropositive, ranging from 2% among those aged &amp;lt;10 years to 66% in those aged 40\u201355 years. We estimated there were 7 outbreaks since the 1970s but none since 2001, resulting in 600 000 infections in the city, none of which were reported. However, we could not definitively conclude whether infections were due to CHIKV or o\u2019nyong-nyong, another alphavirus. In Lambar\u00e9n\u00e9, 117 of 427 (27%) participants were seropositive. Our model identified a single outbreak sometime since 2007, consistent with the only reported CHIKV outbreak in the country. These findings suggest sporadic outbreaks in these settings and that the burden remains undetected or incorrectly attributed.<\/jats:p>","DOI":"10.1093\/infdis\/jiac246","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T02:41:00Z","timestamp":1655433660000},"page":"261-267","source":"Crossref","is-referenced-by-count":31,"title":["Seroepidemiological Reconstruction of Long-term Chikungunya Virus Circulation in Burkina Faso and Gabon"],"prefix":"10.1093","volume":"227","author":[{"given":"Jacqueline Kyungah","family":"Lim","sequence":"first","affiliation":[{"name":"International Vaccine Institute , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery","family":"Ridde","sequence":"additional","affiliation":[{"name":"Montreal School of Public Health , Montreal, Quebec , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selidji Todagbe","family":"Agnandji","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Campus Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9 , Gabon"},{"name":"Institute of Tropical Medicine, University of T\u00fcbingen , T\u00fcbingen , Germany"},{"name":"German Centre for Infection Research, Partner Site T\u00fcbingen , T\u00fcbingen , Germany"},{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9 , Lambar\u00e9n\u00e9 , Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Lell","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Campus Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambar\u00e9n\u00e9 , Gabon"},{"name":"Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna , Vienna , Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seydou","family":"Yaro","sequence":"additional","affiliation":[{"name":"Centre Muraz , Bobo-Dioulasso , Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Seung","family":"Yang","sequence":"additional","affiliation":[{"name":"International Vaccine Institute , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Hoinard","sequence":"additional","affiliation":[{"name":"Institut Pasteur , Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott C","family":"Weaver","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses and Department of Microbiology and Immunology, University of Texas Medical Branch , Galveston, Texas , 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