{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T09:05:57Z","timestamp":1740128757645,"version":"3.37.3"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T00:00:00Z","timestamp":1679097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100011958","name":"Independent Research Fund Denmark","doi-asserted-by":"publisher","award":["7026-0094B"],"award-info":[{"award-number":["7026-0094B"]}],"id":[{"id":"10.13039\/501100011958","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Infection with intestinal whipworms (Trichuris spp.) causes widespread morbidity and may alter responses to enteric and extraintestinal coinfections. Here, we show that Trichuris muris infection in mice increases coinfection with 2 evolutionary divergent enteric pathogens, the bacterium Citrobacter rodentium and the helminth Heligmosomoides polygyrus. Coinfection caused reduced weight gain and promoted type 1\u2013biased inflammation. In contrast, T. muris\u2013infected mice were more resistant to migrating Ascaris suum larvae in the lungs. Our results highlight the divergent nature of pathogen interactions and suggest that whipworm infection is a risk factor for coinfections with other pathogens within the gastrointestinal tract.<\/jats:p>","DOI":"10.1093\/infdis\/jiad063","type":"journal-article","created":{"date-parts":[[2023,3,18]],"date-time":"2023-03-18T03:36:29Z","timestamp":1679110589000},"page":"1428-1432","source":"Crossref","is-referenced-by-count":6,"title":["Whipworm Infection in Mice Increases Coinfection of Enteric Pathogens but Promotes Clearance of <i>Ascaris<\/i> Larvae From the Lungs"],"prefix":"10.1093","volume":"227","author":[{"given":"Nina","family":"Polakovicova","sequence":"first","affiliation":[{"name":"Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen , Frederiksberg , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia Vania","family":"Adji","sequence":"additional","affiliation":[{"name":"Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen , Frederiksberg , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura J","family":"Myhill","sequence":"additional","affiliation":[{"name":"Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen , Frederiksberg , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew R","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen , Frederiksberg , Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,18]]},"reference":[{"key":"2023061501132025900_jiad063-B1","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.ijpara.2021.11.001","article-title":"The yin and yang of human soil-transmitted 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