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Using a retrospective population-based cohort study (339 814 children), bronchiolitis during the first 2 years of life (regardless of etiology and severity) was associated with at least a 3-fold increased risk of RW\/asthma at 2\u20134 years and an increased prevalence of asthma at \u22655 years of age. The risk was similar in children with mild bronchiolitis as in those with hospitalized RSV-bronchiolitis and was higher in children with hospitalized non-RSV-bronchiolitis. The rate of RW\/asthma was higher when bronchiolitis occurred after the first 6 months of life. Our results seem to support the hypothesis of a shared predisposition to bronchiolitis (irrespective of etiology) and RW\/asthma. However, 60% of hospitalized bronchiolitis cases in our setting are due to RSV, which should be paramount in decision-making on imminent RSV prevention strategies.<\/jats:p>","DOI":"10.1093\/infdis\/jiad093","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T22:55:56Z","timestamp":1680648956000},"page":"840-850","source":"Crossref","is-referenced-by-count":29,"title":["Bronchiolitis, Regardless of Its Etiology and Severity, Is Associated With Increased Risk of Asthma: A Population-Based Study"],"prefix":"10.1093","volume":"228","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6519-4905","authenticated-orcid":false,"given":"Cintia","family":"Mu\u00f1oz-Quiles","sequence":"first","affiliation":[{"name":"Vaccines Research Unit, Fundaci\u00f3n para el Fomento de la Investigaci\u00f3n Sanitaria y Biom\u00e9dica de la Comunitat Valenciana, FISABIO\u2013Public Health"},{"name":"CIBER de Epidemiolog\u00eda y Salud P\u00fablica, Instituto de Salud Carlos 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