{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:39:13Z","timestamp":1783640353459,"version":"3.55.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"Supplement_7","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19 AI109945-01"],"award-info":[{"award-number":["U19 AI109945-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01 AI150585"],"award-info":[{"award-number":["P01 AI150585"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Inflammation and cytopenia are commonly observed during Ebola virus (EBOV) infection; however, mechanisms responsible for EBOV-induced cell death remain obscure. While apoptosis and necrosis are already identified as mechanisms of cell death induced by the virus, our study demonstrates that THP-1 monocytes and SupT1 T cells exposed to EBOV undergo pyroptosis and necroptosis, respectively, through a direct contact with EBOV, and also mediate pyroptosis or necroptosis of uninfected bystander cells via indirect effects associated with secreted soluble factors. These results emphasize novel aspects of interactions between EBOV and immune cell populations and provide a better understanding of the immunopathogenesis of EBOV disease.<\/jats:p>","DOI":"10.1093\/infdis\/jiad377","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T05:57:37Z","timestamp":1693547857000},"page":"S582-S586","source":"Crossref","is-referenced-by-count":4,"title":["Interplay of Ebola Virus With Immune Cells Leading to Their Death by Diverse Mechanisms"],"prefix":"10.1093","volume":"228","author":[{"given":"Mathieu","family":"Iampietro","sequence":"first","affiliation":[{"name":"Department of Pathology"},{"name":"Galveston National Laboratory, The University of Texas Medical Branch , Galveston"},{"name":"Department of Virology, Department of Immunology, International Center for Infectiology Research , Lyon , 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