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We estimated HPV type-specific infection detection and clearance in young women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The HPV Infection and Transmission among Couples through Heterosexual activity (HITCH) study is a prospective cohort of 502 college-age women who recently initiated a heterosexual relationship. We tested vaginal samples collected at 6 clinical visits over 24 months for 36 HPV types. Using rates and Kaplan-Meier analysis, we estimated time-to-event statistics with 95% confidence intervals (CIs) for detection of incident infections and clearance of incident and present-at-baseline infections (separately). We conducted analyses at the woman- and HPV-levels, with HPV types grouped by phylogenetic relatedness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>By 24 months, we detected incident infections in 40.4% (CI, 33.4%\u201348.4%) of women. Incident subgenus 1 (43.4; CI, 33.6\u201356.4), 2 (47.1; CI, 39.9\u201355.5), and 3 (46.6; CI, 37.7\u201357.7) infections cleared at similar rates per 1000 infection-months. We observed similar homogeny in HPV-level clearance rates among present-at-baseline infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our analyses provide type-specific infection natural history estimates for cervical cancer prevention planning. HPV-level analyses did not clearly indicate that high oncogenic risk subgenus 2 infections persist longer than their low oncogenic risk subgenera 1 and 3 counterparts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/infdis\/jiad450","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T13:01:17Z","timestamp":1697115677000},"page":"691-706","source":"Crossref","is-referenced-by-count":7,"title":["Detection and Clearance of Type-Specific and Phylogenetically Related Genital Human Papillomavirus Infections in Young Women in New Heterosexual Relationships"],"prefix":"10.1093","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8022-8683","authenticated-orcid":false,"given":"Andrew W","family":"Arthur","sequence":"first","affiliation":[{"name":"Division of Cancer Epidemiology, McGill University , Montr\u00e9al, Qu\u00e9bec , 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