{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T00:19:07Z","timestamp":1786666747491,"version":"build-2736575974"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"Supplement_2","license":[{"start":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T00:00:00Z","timestamp":1699833600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5T32AI100852-10"],"award-info":[{"award-number":["5T32AI100852-10"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["K23AI150378"],"award-info":[{"award-number":["K23AI150378"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Clinical severity scores facilitate comparisons to understand risk factors for severe illness. For the 2022 multinational monkeypox clade IIb virus outbreak, we developed a 7-item Mpox Severity Scoring System (MPOX-SSS) with initial variables refined by data availability and parameter correlation. Application of MPOX-SSS to the first 200 patients diagnosed with mpox revealed higher scores in those treated with tecovirimat, presenting &amp;gt;3 days after symptom onset, and with CD4 counts &amp;lt;200\u2005cells\/mm3. For individuals evaluated repeatedly, serial scores were concordant with clinical observations. The pilot MPOX-SSS demonstrated good discrimination, distinguished change over time, and identified higher scores in expected groups.<\/jats:p>","DOI":"10.1093\/infdis\/jiad492","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T21:21:52Z","timestamp":1699910512000},"page":"S229-S233","source":"Crossref","is-referenced-by-count":21,"title":["Development and Pilot of an Mpox Severity Scoring System"],"prefix":"10.1093","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6987-6412","authenticated-orcid":false,"given":"Jason","family":"Zucker","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Vagelos College of Physicians and Surgeons, Columbia University , NewYork, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"McLean","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Vagelos College of Physicians and Surgeons, Columbia University , 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