{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:25:29Z","timestamp":1792794329208,"version":"4.5.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","license":[{"start":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T00:00:00Z","timestamp":1700092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Innovative Medicines Initiative 2 Joint Undertaking","award":["101034339"],"award-info":[{"award-number":["101034339"]}],"id":[{"id":"https:\/\/ror.org\/019af4n30","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Nanjing Medical University Talents Start-up Grants","award":["NMUR20210009"],"award-info":[{"award-number":["NMUR20210009"]}],"id":[{"id":"https:\/\/ror.org\/059gcgy73","id-type":"ROR","asserted-by":"crossref"}]},{"name":"European Union's Horizon 2020 Research and Innovation Programme"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Individuals with comorbidities are at increased risk of severe respiratory syncytial virus (RSV) infection. We estimated RSV-associated respiratory hospitalization among adults aged \u226545 years with comorbidities in Denmark and Scotland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>By analyzing national hospital and virologic data, we estimated annual RSV-associated hospitalizations by 7 selected comorbidities and ages between 2010 and 2018. We estimated rate ratios of RSV-associated hospitalization for adults with comorbidity than the overall population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In Denmark, annual RSV\u2013associated hospitalization rates per 1000 adults ranged from 3.1 for asthma to 19.4 for chronic kidney disease (CKD). In Scotland, rates ranged from 2.4 for chronic liver disease to 9.0 for chronic obstructive pulmonary disease (COPD). In both countries, we found a 2- to 4-fold increased risk of RSV hospitalization for adults with COPD, ischemic heart disease, stroke, and diabetes; a 1.5- to 3-fold increased risk for asthma; and a 3- to 7-fold increased risk for CKD. RSV hospitalization rates among adults aged 45 to 64 years with COPD, asthma, ischemic heart disease, or CKD were higher than the overall population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study provides important evidence for identifying risk groups and assisting health authorities in RSV vaccination policy making.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/infdis\/jiad510","type":"journal-article","created":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T13:05:51Z","timestamp":1699967151000},"page":"S70-S77","source":"Crossref","is-referenced-by-count":64,"title":["Respiratory Syncytial Virus\u2013Associated Hospitalization in Adults With Comorbidities in 2 European Countries: A Modeling Study"],"prefix":"10.1093","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4622-3691","authenticated-orcid":false,"given":"Richard","family":"Osei-Yeboah","sequence":"first","affiliation":[{"name":"Centre for Global Health, Usher Institute, University of Edinburgh , United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline Klint","family":"Johannesen","sequence":"additional","affiliation":[{"name":"Department of Virology and Microbiological Special Diagnostics, Statens Serum Institut , Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1263-2759","authenticated-orcid":false,"given":"Amanda Marie","family":"Egeskov-Cavling","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Nordsjaellands Hospital Hilleroed, and Department of Public Health, University of Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junru","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Public Health, Nanjing Medical University , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toni","family":"Lehtonen","sequence":"additional","affiliation":[{"name":"Department of Health Security, Finnish Institute for Health and Welfare , Helsinki"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arantxa Urchuegu\u00eda","family":"Fornes","sequence":"additional","affiliation":[{"name":"Vaccine Research Department, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Paget","sequence":"additional","affiliation":[{"name":"Department of Primary Care, Netherlands Institute for Health Services Research , Utrecht"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thea K","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Virology and Microbiological Special Diagnostics, Statens Serum Institut , Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8762-2421","authenticated-orcid":false,"given":"Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"Centre for Global Health, Usher Institute, University of Edinburgh , United Kingdom"},{"name":"School of Public Health, Nanjing Medical University , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9432-9100","authenticated-orcid":false,"given":"Harish","family":"Nair","sequence":"additional","affiliation":[{"name":"Centre for Global Health, Usher Institute, University of Edinburgh , United 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