{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:54:55Z","timestamp":1787849695873,"version":"build-2784847793"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"Supplement_2","license":[{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>We describe diverse clinical characteristics and course of confirmed mpox cases managed in a Nigerian tertiary health facility.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Clinical and epidemiologic data were analyzed, highlighting the unusual presentations of polymerase chain reaction (PCR)\u2013confirmed mpox cases observed during the 2022 outbreak.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Out of 17 suspected cases, 13 (76.4%) were PCR confirmed for mpox. The mean \u00b1 SD age for the participants was 28.62 \u00b1 10.29 years (range, 2\u201355), of which 9 (64.3%) were male. Of the 13 PCR-confirmed cases, 5 (38.5%) had varicella zoster virus coinfection, 2 (15.4%) had HIV coinfection, and 1 (7.7%) had diabetes mellitus comorbidity. All patients experienced rash, with 6 (46.2%) having significant genital lesions and 1 (7.7%) having a severe perianal lesion. A lack of prodromal symptoms was reported in 3 (23.1%), and a prolonged prodrome (&amp;gt;1 week) occurred in 5 (38.5%). Skin lesions were polymorphic in 6 (46.2%), and solitary skin lesions occurred in 3 (23.1%), which persisted for &amp;gt;120 days in 7.7%.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Clinical recognition, diagnosis, and prevention remain a concern in resource-limited settings. Our findings highlight the need to further evaluate unusual skin lesions and to include mpox screening for genital skin lesions that are presumed to be sexually transmitted infections. Revision of clinical case definition and enhanced surveillance are key to early recognition and prevention of spread.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiad607","type":"journal-article","created":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T19:32:04Z","timestamp":1703878324000},"page":"S181-S187","source":"Crossref","is-referenced-by-count":5,"title":["Atypical Mpox in a Nigerian Tertiary Health Facility"],"prefix":"10.1093","volume":"229","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4814-8384","authenticated-orcid":false,"given":"Nneka M","family":"Chika-Igwenyi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital Abakaliki"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uche S","family":"Unigwe","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital 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K","family":"Ojide","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Alex Ekwueme Federal University Teaching Hospital Abakaliki"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred F","family":"Una","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, University of Nigeria Teaching Hospital , Ituku\/Ozalla"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikaodiri","family":"Igwenyi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital Abakaliki"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyrian S","family":"Chukwu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital Abakaliki"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel 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