{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:04:57Z","timestamp":1786716297360,"version":"build-2736575974"},"reference-count":49,"publisher":"Oxford University Press (OUP)","issue":"1","funder":[{"DOI":"10.13039\/100000030","name":"US Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["CDC-RFA-IP16-004"],"award-info":[{"award-number":["CDC-RFA-IP16-004"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Most acute gastroenteritis (AGE) episodes in children in the United States are attributed to norovirus, whereas very little information is available on adenovirus 40\/41 (AdV40\/41), astrovirus, or sapovirus. The New Vaccine Surveillance Network (NVSN) conducted prospective, active, population-based AGE surveillance in young children.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We tested and typed stool specimens collected between December 2011 and June 2016 from 1 NVSN site in Kansas City for the 3 viruses, and calculated hospitalization and emergency department (ED) detection rates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 3205 collected specimens, 2453 (76.5%) were from AGE patients (339 inpatients and 2114 ED patients) and 752 (23.5%) were from healthy controls. In patients with AGE, astrovirus was detected in 94 (3.8%), sapovirus in 252 (10.3%), and AdV40\/41 in 101 (4.5%) of 2249 patients. In healthy controls, astrovirus was detected in 13 (1.7%) and sapovirus in 15 (2.0%) specimens. Astrovirus type 1 (37.7%) and genogroup I sapoviruses (59.3%) were most prevalent. Hospitalization rates were 5 (AdV40\/41), 4 (astrovirus), and 8 (sapovirus) per 100 000 children &amp;lt;11 years old, whereas ED rates were 2.4 (AdV40\/41), 1.9 (astrovirus), and 5.3 (sapovirus) per 1000 children &amp;lt;5 years old.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Overall, AdV40\/41, astrovirus, and sapovirus were detected in 18.6% of AGE in a large pediatric hospital in Kansas City.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiae251","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T17:51:56Z","timestamp":1715190716000},"page":"186-195","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and Genetic Diversity of Adenovirus 40\/41, Astrovirus, and Sapovirus in Children With Acute Gastroenteritis in Kansas City, 2011\u20132016"],"prefix":"10.1093","volume":"231","author":[{"given":"Marta","family":"Diez-Valcarce","sequence":"first","affiliation":[{"name":"Division of Viral Diseases, Centers for Disease Control and Prevention"},{"name":"National Foundation for the Centers for Disease Control and Prevention Inc , Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L","family":"Cannon","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, Centers for Disease Control and Prevention"},{"name":"National Foundation for the Centers for Disease Control and Prevention Inc , Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Browne","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, Centers for Disease Control and Prevention"},{"name":"National Foundation for the Centers for Disease Control and Prevention Inc , Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenny","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, Centers for Disease Control and Prevention"},{"name":"National Foundation for the Centers for Disease Control and Prevention Inc , Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J","family":"Harrison","sequence":"additional","affiliation":[{"name":"Children's Mercy Hospital , Kansas City, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E","family":"Moffatt","sequence":"additional","affiliation":[{"name":"Children's Mercy Hospital , Kansas City, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Weltmer","sequence":"additional","affiliation":[{"name":"Children's Mercy Hospital , Kansas City, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian 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