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Human infections with clade 2.3.4.4b viruses from exposures to infected poultry or dairy cattle have resulted in a wide spectrum of illness severity, from conjunctivitis or mild respiratory illness to severe and fatal pneumonia in different countries. Vigilance, and stronger global virologic surveillance among birds, poultry, terrestrial and marine mammals, and humans, with virus characterization and rapid data sharing, is needed to inform the threat of clade 2.3.4.4b viruses, as they continue to evolve, to public health.<\/jats:p>","DOI":"10.1093\/infdis\/jiae379","type":"journal-article","created":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T18:57:39Z","timestamp":1721933859000},"page":"533-542","source":"Crossref","is-referenced-by-count":140,"title":["An Update on Highly Pathogenic Avian Influenza A(H5N1) Virus, Clade 2.3.4.4b"],"prefix":"10.1093","volume":"230","author":[{"given":"Richard J","family":"Webby","sequence":"first","affiliation":[{"name":"World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds, St Jude Children's Research Hospital , Memphis, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy 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