{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:45:59Z","timestamp":1792640759969,"version":"4.5.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI093692"],"award-info":[{"award-number":["R01AI093692"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI148359"],"award-info":[{"award-number":["R01AI148359"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We assessed neutralizing antibody responses in a well-characterized cohort of 60 women with different Chlamydia trachomatis infection outcomes noted at a treatment visit and 3-month follow-up. We found varying rates of neutralization (inhibition of C trachomatis) in sera at different dilution levels and varying neutralizing antibody titers across outcomes. Median neutralization rates were significantly higher in sera at high dilutions (1:320\u20131:1280) from women with spontaneous resolution vs persisting infection before treatment (all P &amp;lt; .05). These findings suggest that neutralizing antibody responses may contribute to protective immunity against chlamydia.<\/jats:p>","DOI":"10.1093\/infdis\/jiae519","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T16:16:59Z","timestamp":1729613819000},"page":"e531-e535","source":"Crossref","is-referenced-by-count":7,"title":["Neutralizing Antibody Responses to <i>Chlamydia trachomatis<\/i> in Women and Associations With Chlamydia Outcomes"],"prefix":"10.1093","volume":"231","author":[{"given":"Hong","family":"Yu","sequence":"first","affiliation":[{"name":"British Columbia Centre for Disease Control, University of British Columbia , Vancouver ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0603-2404","authenticated-orcid":false,"given":"William M","family":"Geisler","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at 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