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We show that live attenuated measles virus (LAMV) RNA is frequently detected in the respiratory tract 7\u201321 days after subcutaneous measles-mumps-rubella (MMR) vaccination in healthy children (n = 5\/20) and macaques (n = 6\/8). Replicating LAMV was isolated from the lungs of 2 macaques, with no evidence of transmission to unvaccinated individuals. These observations suggest that LAMV in the respiratory tract may play a role in the development of robust mucosal immunity following MMR vaccination.<\/jats:p>","DOI":"10.1093\/infdis\/jiae537","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T19:35:10Z","timestamp":1730921710000},"page":"1089-1093","source":"Crossref","is-referenced-by-count":5,"title":["Detection of Live Attenuated Measles Virus in the Respiratory Tract Following Subcutaneous Measles-Mumps-Rubella Vaccination"],"prefix":"10.1093","volume":"231","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1607-1335","authenticated-orcid":false,"given":"Timothy A","family":"Watkins","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, Yale School of Medicine , New Haven, Connecticut ,","place":["USA"]},{"name":"Department of Immunobiology, Yale School of Medicine , New Haven, Connecticut 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