{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T03:49:13Z","timestamp":1792554553007,"version":"4.5.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"3","funder":[{"DOI":"10.13039\/100005224","name":"National Center for Immunization and Respiratory Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005224","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["75D30120R68013"],"award-info":[{"award-number":["75D30120R68013"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011624","name":"Marshfield Clinic Research Laboratory","doi-asserted-by":"publisher","award":["75D30120C08379"],"award-info":[{"award-number":["75D30120C08379"]}],"id":[{"id":"10.13039\/100011624","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007899","name":"University of Arizona","doi-asserted-by":"publisher","award":["75D30120C08150"],"award-info":[{"award-number":["75D30120C08150"]}],"id":[{"id":"10.13039\/100007899","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008769","name":"Abt Associates, Inc)","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Data are limited on whether vaccination reduces post COVID conditions (PCCs) risk after less severe nonhospitalized coronavirus disease 2019 (COVID-19). This study assessed whether COVID-19 vaccination protected against PCCs in persons with mild initial infections during Delta and Omicron variant predominance.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This study utilized a case-control design, nested within the HEROES-RECOVER cohort. Participants aged \u226518 years with test\u2013confirmed severe acute respiratory syndrome coronavirus disease 2 (SARS-CoV-2) between 28 June 2021 and 14 September 2022 were surveyed for PCCs, defined by symptoms lasting &amp;gt;4 weeks after initial infection. Cases self-reported PCCs and controls self-reported no PCCs. The exposure was messenger RNA (mRNA) COVID-19 vaccination (2 or 3 monovalent doses). Odds of PCCs among vaccinated and unvaccinated persons were compared with logistic regression.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 936 participants, 23.6% reported PCCs and 83.2% were vaccinated. Participants who received 3 vaccine doses had lower odds of PCC-related gastrointestinal, neurological, and other symptoms compared to unvaccinated participants (adjusted odds ratio [95% confidence interval]: 0.37 [.16\u2013.85], 0.56 [.32\u2013.97], and 0.48 [.25\u2013.91], respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>COVID-19 vaccination protected against development of PCCs among persons with mild infection during both Delta and Omicron variant predominance, supporting vaccination as an important PCCs prevention tool.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiae556","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T22:43:17Z","timestamp":1731451397000},"page":"665-676","source":"Crossref","is-referenced-by-count":6,"title":["Association of Messenger RNA Coronavirus Disease 2019 (COVID-19) Vaccination and Reductions in Post COVID Conditions Following Severe Acute Respiratory Syndrome Coronavirus 2 Infection in a US Prospective Cohort of Essential Workers"],"prefix":"10.1093","volume":"231","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9557-2690","authenticated-orcid":false,"given":"Josephine","family":"Mak","sequence":"first","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention , Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0699-2103","authenticated-orcid":false,"given":"Sana","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona , Tucson, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2684-8846","authenticated-orcid":false,"given":"Amadea","family":"Britton","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention , Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spencer","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor Scott and White Health , Temple, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2857-376X","authenticated-orcid":false,"given":"Lisa","family":"Gwynn","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Leonard M. Miller School of Medicine, University of Miami , Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine D","family":"Ellingson","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona , Tucson, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Meece","sequence":"additional","affiliation":[{"name":"Marshfield Clinic Research Institute , Marshfield, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4430-6760","authenticated-orcid":false,"given":"Leora R","family":"Feldstein","sequence":"additional","affiliation":[{"name":"National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention , Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4130-0793","authenticated-orcid":false,"given":"Harmony","family":"Tyner","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Disease, St Luke's Regional Health Care System , Duluth, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J","family":"Edwards","sequence":"additional","affiliation":[{"name":"Abt Associates Inc , Rockville, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4505-2907","authenticated-orcid":false,"given":"Matthew S","family":"Thiese","sequence":"additional","affiliation":[{"name":"Rocky Mountain Center for Occupational and Environmental Health, Division of Occupational and Environmental Health, University of Utah Health , Salt Lake City, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5747-4643","authenticated-orcid":false,"given":"Allison","family":"Naleway","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Center for Health Research , Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3952-9230","authenticated-orcid":false,"given":"Manjusha","family":"Gaglani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor Scott and White Health , Temple, Texas"},{"name":"Department of Pediatrics, Baylor College of Medicine, Temple, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Solle","sequence":"additional","affiliation":[{"name":"Department of Medicine, Leonard M. 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