{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:36:50Z","timestamp":1771047410834,"version":"3.50.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Montefiore-Einstein Comprehensive Cancer Center","award":["R01-CA230331"],"award-info":[{"award-number":["R01-CA230331"]}]},{"name":"Montefiore-Einstein Comprehensive Cancer Center","award":["U01-AI-103401"],"award-info":[{"award-number":["U01-AI-103401"]}]},{"name":"Montefiore-Einstein Comprehensive Cancer Center","award":["U01-AI-103408"],"award-info":[{"award-number":["U01-AI-103408"]}]},{"name":"Atlanta WIHS","award":["U01-AI-035004"],"award-info":[{"award-number":["U01-AI-035004"]}]},{"name":"Bronx WIHS","award":["U01-AI-031834"],"award-info":[{"award-number":["U01-AI-031834"]}]},{"name":"Brooklyn WIHS","award":["U01-AI-034993"],"award-info":[{"award-number":["U01-AI-034993"]}]},{"name":"Chicago WIHS","award":["U01-AI-034994"],"award-info":[{"award-number":["U01-AI-034994"]}]},{"name":"Chicago WIHS","award":["U01-AI-103397"],"award-info":[{"award-number":["U01-AI-103397"]}]},{"name":"Chicago WIHS","award":["U01-AI-103390"],"award-info":[{"award-number":["U01-AI-103390"]}]},{"name":"Chicago WIHS","award":["U01-AI-034989"],"award-info":[{"award-number":["U01-AI-034989"]}]},{"name":"WIHS Northern California","award":["U01-AI-042590"],"award-info":[{"award-number":["U01-AI-042590"]}]},{"name":"WIHS Data Management and Analysis Center","award":["U01-HD-032632"],"award-info":[{"award-number":["U01-HD-032632"]}]},{"name":"Southern California WIHS"},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["P30-AI-050410"],"award-info":[{"award-number":["P30-AI-050410"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute on Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and other Communication Disorders","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIH Office of Research on Women's Health;","award":["UL1-TR000004"],"award-info":[{"award-number":["UL1-TR000004"]}]},{"name":"NIH Office of Research on Women's Health;","award":["UL1-TR000454"],"award-info":[{"award-number":["UL1-TR000454"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We studied cervicovaginal \u03b2\/\u03b3\u2013human papillomavirus (HPV) and their relationship to cervical precancer in women with human immunodeficiency virus; having previously reported strong positive associations of \u03b2\/\u03b3-HPV with incident head and neck cancer in the general population. Case patients (n = 124) had cervical intraepithelial neoplasia (CIN) 3 or 2. Controls (n = 247) were individually matched 2:1 to case patients. Unexpectedly, multivariate analyses found strong inverse associations between \u03b2\/\u03b3-HPV and CIN-2\/3 (odds ratio, 0.19 [95% confidence interval, .04\u2013.86]; P = .03; Ptrend &amp;lt; .01]). This is, to our knowledge, the first study of \u03b2\/\u03b3-HPV and cervical precancer. If confirmed, a strong inverse (protective) association would be of potential clinical and biologic relevance.<\/jats:p>","DOI":"10.1093\/infdis\/jiae588","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T11:14:58Z","timestamp":1732706098000},"page":"595-599","source":"Crossref","is-referenced-by-count":3,"title":["Case-Control Study of Cervicovaginal \u03b2\/\u03b3\u2013Human Papillomavirus Infection in Women With Human Immunodeficiency Virus and Its Relation to Incident Cervical Precancer"],"prefix":"10.1093","volume":"231","author":[{"given":"Howard D","family":"Strickler","sequence":"first","affiliation":[{"name":"Dept of Epidemiology & Population Health, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mykhaylo","family":"Usyk","sequence":"additional","affiliation":[{"name":"Dept of Pediatrics, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isam-Eldin","family":"Eltoum","sequence":"additional","affiliation":[{"name":"Dept of Pathology, University of Alabama , Birmingham, Alabama ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Bachman","sequence":"additional","affiliation":[{"name":"Dept of Pediatrics, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy A","family":"Hessol","sequence":"additional","affiliation":[{"name":"Dept of Clinical Pharmacy, University of California , San Francisco, California ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Flowers","sequence":"additional","affiliation":[{"name":"Dept Gynecology & Obstetrics, Emory University School of Medicine , Atlanta, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Rahangdale","sequence":"additional","affiliation":[{"name":"Dept of Obstetrics & Gynecology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3505-643X","authenticated-orcid":false,"given":"Jessica M","family":"Atrio","sequence":"additional","affiliation":[{"name":"Dept of Obstetrics and Gynecology, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0872-0307","authenticated-orcid":false,"given":"Catalina","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Dept of Infectious Diseases, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Minkoff","sequence":"additional","affiliation":[{"name":"Maimonides Medical Center, Department of Obstetrics & Gynecology , Brooklyn, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adaora A","family":"Adimora","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2735-1903","authenticated-orcid":false,"given":"Igho","family":"Ofotokun","sequence":"additional","affiliation":[{"name":"Dept of Medicine, Emory University School of Medicine, Atlanta, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0417-4000","authenticated-orcid":false,"given":"Marla J","family":"Keller","sequence":"additional","affiliation":[{"name":"Dept of Medicine, Albert Einstein College of Medicine\/Montefiore Medical Center, Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Fischl","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Miami Miller School of Medicine , Miami, Florida ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7002-357X","authenticated-orcid":false,"given":"Sadeep","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Dept of Pathology, University of Alabama , Birmingham, Alabama ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7922-3503","authenticated-orcid":false,"given":"Rodney","family":"Wright","sequence":"additional","affiliation":[{"name":"Dept of Obstetrics and Gynecology, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gypsyamber","family":"D\u2019Souza","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, Maryland ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine","family":"Sanchez-Keeland","sequence":"additional","affiliation":[{"name":"University of Southern California, Department of Obstetrics & Gynecology, Los Angeles, California ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianhong","family":"Xie","sequence":"additional","affiliation":[{"name":"Dept of Epidemiology & Population Health, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaonan","family":"Xue","sequence":"additional","affiliation":[{"name":"Dept of Epidemiology & Population Health, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Anastos","sequence":"additional","affiliation":[{"name":"Dept of Epidemiology & Population Health, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]},{"name":"Dept of Medicine, Albert Einstein College of Medicine\/Montefiore Medical Center, Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8486-9464","authenticated-orcid":false,"given":"L Stewart","family":"Massad","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine, Department of Obstetrics & Gynecology, St Louis, Missouri ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel M","family":"Palefsky","sequence":"additional","affiliation":[{"name":"Dept of Medicine, University of California, San Francisco, California ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8376-8458","authenticated-orcid":false,"given":"Robert D","family":"Burk","sequence":"additional","affiliation":[{"name":"Dept of Epidemiology & Population Health, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]},{"name":"Dept of Pediatrics, Albert Einstein College of Medicine\/Montefiore Medical Center , Bronx, New York ,","place":["USA"]},{"name":"Dept of Microbiology & Immunology, Albert Einstein College of Medicine\/Montefiore Medical Center, Bronx, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"key":"2025031709182351500_jiae588-B1","author":"Panel on Opportunistic Infections in Adults and Adolescents with HIV"},{"key":"2025031709182351500_jiae588-B2","doi-asserted-by":"crossref","first-page":"866","DOI":"10.7326\/M17-2499","article-title":"Projected cancer incidence rates and burden of incident cancer cases in HIV-infected adults in the United States through 2030","volume":"168","author":"Shiels","year":"2018","journal-title":"Ann Intern Med"},{"key":"2025031709182351500_jiae588-B3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3389\/fonc.2019.00355","article-title":"Mucosal and cutaneous human papillomavirus infections and cancer biology","volume":"9","author":"Gheit","year":"2019","journal-title":"Front Oncol"},{"key":"2025031709182351500_jiae588-B4","first-page":"513","article-title":"Incidence of skin cancer in 5356 patients following organ transplantation","volume":"143","author":"Lindelof","year":"2000","journal-title":"Br J Dermatol"},{"key":"2025031709182351500_jiae588-B5","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1111\/ajt.14537","article-title":"Human papillomavirus and posttransplantation cutaneous squamous cell carcinoma: a multicenter, prospective cohort study","volume":"18","author":"Bouwes Bavinck","year":"2018","journal-title":"Am J Transplant"},{"key":"2025031709182351500_jiae588-B6","doi-asserted-by":"crossref","first-page":"e1003924","DOI":"10.1371\/journal.ppat.1003924","article-title":"Protective vaccination against papillomavirus-induced skin tumors under immunocompetent and immunosuppressive conditions: a preclinical study using a natural outbred animal model","volume":"10","author":"Vinzon","year":"2014","journal-title":"PLoS Pathog"},{"key":"2025031709182351500_jiae588-B7","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.virusres.2016.11.020","article-title":"Developments in L2-based human papillomavirus (HPV) vaccines","volume":"231","author":"Schellenbacher","year":"2017","journal-title":"Virus Res"},{"key":"2025031709182351500_jiae588-B8","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1001\/jamaoncol.2015.5504","article-title":"Associations of oral alpha-, beta-, and gamma-human papillomavirus types with risk of incident head and neck cancer","volume":"2","author":"Agalliu","year":"2016","journal-title":"JAMA Oncol"},{"key":"2025031709182351500_jiae588-B9","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.3390\/v15091967","article-title":"Broad-spectrum detection of HPV in male genital samples using target-enriched whole-genome sequencing","volume":"15","author":"Li","year":"2023","journal-title":"Viruses"},{"key":"2025031709182351500_jiae588-B10","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1158\/1055-9965.EPI-17-0081","article-title":"Cervical infection with cutatneous beta and mucosal alpha papillomaviruses","volume":"26","author":"Sichero","year":"2017","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2025031709182351500_jiae588-B11","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1093\/ofid\/ofw216","article-title":"Prevalence and transmission of beta and gamma human papillomavirus in heterosexual couples","volume":"4","author":"Moscicki","year":"2017","journal-title":"Open Forum Infect Dis"},{"key":"2025031709182351500_jiae588-B12","first-page":"1013","article-title":"The women's interagency HIV study: an observational cohort brings clinical sciences to the bench","volume":"12","author":"Bacon","year":"2005","journal-title":"Clin Diagn Lab Immunol"},{"key":"2025031709182351500_jiae588-B13","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1158\/1055-9965.EPI-17-1051","article-title":"Methylation of high-risk human papillomavirus genomes are associated with cervical precancer in HIV-positive women","volume":"27","author":"Gradissimo","year":"2018","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2025031709182351500_jiae588-B14","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1158\/1055-9965.EPI-21-1000","article-title":"Cutaneous \u03b2 HPVs, sun exposure, and risk of squamous and basal cell skin cancers in Australia","volume":"31","author":"Kricker","year":"2022","journal-title":"Cancer Epidemiol Biomarkers Prev"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jid\/advance-article-pdf\/doi\/10.1093\/infdis\/jiae588\/60829961\/jiae588.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jid\/article-pdf\/231\/3\/595\/60829961\/jiae588.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jid\/article-pdf\/231\/3\/595\/60829961\/jiae588.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T09:19:03Z","timestamp":1742203143000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/231\/3\/595\/7909255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":14,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,11,27]]},"published-print":{"date-parts":[[2025,3,17]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jiae588","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"value":"0022-1899","type":"print"},{"value":"1537-6613","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,3,15]]},"published":{"date-parts":[[2024,11,27]]}}}