{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:38:49Z","timestamp":1792651129215,"version":"4.5.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Dengue is the most widespread vector-borne viral infection globally and a serious public health problem. The 2023\u20132024 dengue outbreak across Latin America has drastically impacted Peru, including previously unaffected areas such as metropolitan Lima and Amazonian rural communities, presumably due to climate change. Research studies conducted in Iquitos, the largest city in the Peruvian Amazon, showed that ultra-low-volume pyrethroid spray applications against the dengue vector Aedes aegypti were effective when adequate coverage and quality control were carried out. Insecticide-treated curtains were not effective at controlling dengue transmission in Iquitos, whereas the use of passive spatial repellent emanators demonstrated 34% protective efficacy against Aedes-borne virus infection. In modeling studies, targeted indoor residual spray strategies showed promising reductions in dengue transmission, which require empirical evaluation. Trials conducted in Iquitos have shown that larval control alone is not sufficient to control Ae. aegypti, urging that government programs must consider integrated vector management.<\/jats:p>","DOI":"10.1093\/infdis\/jiae602","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T20:24:14Z","timestamp":1733257454000},"page":"S31-S38","source":"Crossref","is-referenced-by-count":7,"title":["A Review of <i>Aedes aegypti<\/i> Control in Peru: Approaches and Lessons Learned"],"prefix":"10.1093","volume":"231","author":[{"given":"Helvio","family":"Astete","sequence":"first","affiliation":[{"name":"Entomology Department, U.S. Naval Medical Research Unit SOUTH , Lima ,","place":["Peru"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0091-1272","authenticated-orcid":false,"given":"Carmen","family":"Flores-Mendoza","sequence":"additional","affiliation":[{"name":"Entomology Department, U.S. Naval Medical Research Unit SOUTH , Lima ,","place":["Peru"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor M","family":"L\u00f3pez-Sifuentes","sequence":"additional","affiliation":[{"name":"Entomology Department, U.S. Naval Medical Research Unit SOUTH , Lima ,","place":["Peru"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gissella M","family":"V\u00e1squez","sequence":"additional","affiliation":[{"name":"Entomology Department, U.S. Naval Medical Research Unit SOUTH , Lima ,","place":["Peru"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6224-5984","authenticated-orcid":false,"given":"Amy C","family":"Morrison","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"key":"2025021015551210900_jiae602-B1","article-title":"Pan American Health Organization"},{"key":"2025021015551210900_jiae602-B2","article-title":"Pan American Health Organization\/World Health Organization"},{"key":"2025021015551210900_jiae602-B3","first-page":"1614","article-title":"Dengue cases surge in Latin America and Caribbean","volume":"331","author":"Harris","year":"2024","journal-title":"JAMA"},{"key":"2025021015551210900_jiae602-B4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ijid.2016.01.015","article-title":"A comparative study on active and passive epidemiological surveillance for dengue in five countries of Latin America","volume":"44","author":"Sarti","year":"2016","journal-title":"Int J Infect Dis"},{"key":"2025021015551210900_jiae602-B5","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/tmi.13217","article-title":"Interventions for the control of Aedes aegypti in Latin America and the Caribbean: systematic review and meta-analysis","volume":"24","author":"Bardach","year":"2019","journal-title":"Trop Med Int Health"},{"key":"2025021015551210900_jiae602-B6","article-title":"Instituto de Salud P\u00fablica de Chile"},{"key":"2025021015551210900_jiae602-B7","first-page":"145","article-title":"Dengue en el Per\u00fa: cr\u00f3nica de epidemias recurrentes (1990\u20132023), el virus, el Aedes aegypti y sus determinantes, \u00bfa d\u00f3nde vamos? An Fac Med (Lima Peru: 1990)","volume":"84","author":"S\u00e1nchez","year":"2023","journal-title":"Universidad Nacional Mayor de San Marcos, Vicerectorado de Investigacion"},{"key":"2025021015551210900_jiae602-B8","first-page":"201","article-title":"First documented outbreak of dengue in the Peruvian Amazon region","volume":"26","author":"Phillips","year":"1992","journal-title":"Bull Pan Am Health Organ"},{"key":"2025021015551210900_jiae602-B9"},{"key":"2025021015551210900_jiae602-B10","first-page":"3","article-title":"Estrategias integradas para el control del dengue en el Per\u00fa, \u00bfhay nuevas opciones? An Fac Med (Lima Peru: 1990)","volume":"85","author":"Cabezas","year":"2024","journal-title":"Universidad Nacional Mayor de San Marcos, Vicerectorado de Investigacion"},{"key":"2025021015551210900_jiae602-B11","doi-asserted-by":"crossref","first-page":"e68","DOI":"10.1371\/journal.pmed.0050068","article-title":"Defining challenges and proposing solutions for control of the virus vector Aedes aegypti","volume":"5","author":"Morrison","year":"2008","journal-title":"PLoS Med"},{"key":"2025021015551210900_jiae602-B12","doi-asserted-by":"crossref","first-page":"e0003655","DOI":"10.1371\/journal.pntd.0003655","article-title":"A critical assessment of vector control for dengue prevention","volume":"9","author":"Achee","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B13","article-title":"Ministerio de Salud"},{"key":"2025021015551210900_jiae602-B14","doi-asserted-by":"crossref","first-page":"494","DOI":"10.4269\/ajtmh.2003.69.494","article-title":"Characteristics of the spatial pattern of the dengue vector, Aedes aegypti, in Iquitos, Peru","volume":"69","author":"Getis","year":"2003","journal-title":"Am J Trop Med Hyg"},{"key":"2025021015551210900_jiae602-B15","doi-asserted-by":"crossref","first-page":"e3038","DOI":"10.1371\/journal.pntd.0003038","article-title":"Shifting patterns of Aedes aegypti fine scale spatial clustering in Iquitos, Peru","volume":"8","author":"LaCon","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B16","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1603\/0022-2585-41.3.502","article-title":"Evaluation of a sampling methodology for rapid assessment of Aedes aegypti infestation levels in Iquitos, Peru","volume":"41","author":"Morrison","year":"2004","journal-title":"J Med Entomol"},{"key":"2025021015551210900_jiae602-B17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.4269\/ajtmh.1997.56.159","article-title":"Pupal survey: an epidemiologically significant surveillance method for Aedes aegypti: an example using data from Trinidad","volume":"56","author":"Focks","year":"1997","journal-title":"Am J Trop Med Hyg"},{"issue":"Suppl 1","key":"2025021015551210900_jiae602-B18","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1179\/136485906X105462","article-title":"Pupal\/demographic surveys to inform dengue-vector control","volume":"100","author":"Nathan","year":"2006","journal-title":"Ann Trop Med Parasitol"},{"key":"2025021015551210900_jiae602-B19","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1603\/0022-2585-41.6.1123","article-title":"Temporal and geographic patterns of Aedes aegypti (Diptera: Culicidae) production in Iquitos, Peru","volume":"41","author":"Morrison","year":"2004","journal-title":"J Med Entomol"},{"issue":"Suppl 1","key":"2025021015551210900_jiae602-B20","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1179\/136485906X105534","article-title":"Aedes aegypti (Diptera: Culicidae) production from non-residential sites in the Amazonian city of Iquitos, Peru","volume":"100","author":"Morrison","year":"2006","journal-title":"Ann Trop Med Parasitol"},{"key":"2025021015551210900_jiae602-B21","doi-asserted-by":"crossref","first-page":"e1632","DOI":"10.1371\/journal.pntd.0001632","article-title":"Linking oviposition site choice to offspring fitness in Aedes aegypti: consequences for targeted larval control of dengue vectors","volume":"6","author":"Wong","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B22","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1603\/ME10149","article-title":"Sampling considerations for designing Aedes aegypti (Diptera: Culicidae) oviposition studies in Iquitos, Peru: substrate preference, diurnal periodicity, and gonotrophic cycle length","volume":"48","author":"Wong","year":"2011","journal-title":"J Med Entomol"},{"key":"2025021015551210900_jiae602-B23","doi-asserted-by":"crossref","first-page":"e1015","DOI":"10.1371\/journal.pntd.0001015","article-title":"Oviposition site selection by the dengue vector Aedes aegypti and its implications for dengue control","volume":"5","author":"Wong","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B24","doi-asserted-by":"crossref","first-page":"e3033","DOI":"10.1371\/journal.pntd.0003033","article-title":"Patterns of geographic expansion of Aedes aegypti in the Peruvian Amazon","volume":"8","author":"Guagliardo","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B25","doi-asserted-by":"crossref","first-page":"e0003648","DOI":"10.1371\/journal.pntd.0003648","article-title":"River boats contribute to the regional spread of the dengue vector Aedes aegypti in the Peruvian Amazon","volume":"9","author":"Guagliardo","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B26","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1093\/jme\/tjv048","article-title":"Evidence for Aedes aegypti (Diptera: Culicidae) oviposition on boats in the Peruvian Amazon","volume":"52","author":"Guagliardo","year":"2015","journal-title":"J Med Entomol"},{"key":"2025021015551210900_jiae602-B27","doi-asserted-by":"crossref","first-page":"e0007552","DOI":"10.1371\/journal.pntd.0007552","article-title":"The genetic structure of Aedes aegypti populations is driven by boat traffic in the Peruvian Amazon","volume":"13","author":"Guagliardo","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B28","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1073\/pnas.1213349110","article-title":"House-to-house human movement drives dengue virus transmission","volume":"110","author":"Stoddard","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2025021015551210900_jiae602-B29","doi-asserted-by":"crossref","first-page":"e0005429","DOI":"10.1371\/journal.pntd.0005429","article-title":"The relationship between entomological indicators of Aedes aegypti abundance and dengue virus infection","volume":"11","author":"Cromwell","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B30","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1111\/eva.13269","article-title":"Rapid evolution of knockdown resistance haplotypes in response to pyrethroid selection in Aedes aegypti","volume":"14","author":"Baltzegar","year":"2021","journal-title":"Evol Appl"},{"key":"2025021015551210900_jiae602-B31","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1186\/s13071-019-3739-6","article-title":"Susceptibility to insecticides and resistance mechanisms in three populations of Aedes aegypti from Peru","volume":"12","author":"Pinto","year":"2019","journal-title":"Parasit Vectors"},{"key":"2025021015551210900_jiae602-B32","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s13071-022-05310-x","article-title":"First national-scale evaluation of temephos resistance in Aedes aegypti in Peru.","volume":"15","author":"Palomino","year":"2022","journal-title":"Parasit Vectors"},{"key":"2025021015551210900_jiae602-B33","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1093\/jmedent\/42.4.620","article-title":"Potential use of pyriproxyfen for control of Aedes aegypti (Diptera: Culicidae) in Iquitos, Peru","volume":"42","author":"Sihuincha","year":"2005","journal-title":"J Med Entomol"},{"key":"2025021015551210900_jiae602-B34","first-page":"158","article-title":"Evaluaci\u00f3n del efecto residual del Temephos en larvas de Aedes aegypti en Lima, Per\u00fa","volume":"23","author":"Palomino S","year":"2006","journal-title":"Rev Peru Med Exp Salud Publica"},{"key":"2025021015551210900_jiae602-B35","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1111\/j.1365-3156.2009.02341.x","article-title":"Reducing costs and operational constraints of dengue vector control by targeting productive breeding places: a multi-country non-inferiority cluster randomized trial","volume":"14","author":"Tun-Lin","year":"2009","journal-title":"Trop Med Int Health"},{"key":"2025021015551210900_jiae602-B36","doi-asserted-by":"publisher","first-page":"24","DOI":"10.24265\/horizmed.2017.v17n4.05","article-title":"Evaluaci\u00f3n del efecto residual del temephos en larvas de Aedes aegypti en Lima. Per\u00fa","volume":"17","author":"P\u00e9rez","year":"2017","journal-title":"Horiz Med"},{"key":"2025021015551210900_jiae602-B37","doi-asserted-by":"crossref","first-page":"11530","DOI":"10.1073\/pnas.0901369106","article-title":"Using adult mosquitoes to transfer insecticides to Aedes aegypti larval habitats","volume":"106","author":"Devine","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2025021015551210900_jiae602-B38","doi-asserted-by":"crossref","first-page":"e3003","DOI":"10.1371\/journal.pntd.0003003","article-title":"Long-term and seasonal dynamics of dengue in Iquitos, Peru","volume":"8","author":"Stoddard","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B39","doi-asserted-by":"crossref","first-page":"e0007255","DOI":"10.1371\/journal.pntd.0007255","article-title":"Estimating the impact of city-wide Aedes aegypti population control: an observational study in Iquitos, Peru","volume":"13","author":"Reiner","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B40","doi-asserted-by":"crossref","first-page":"e0006378","DOI":"10.1371\/journal.pntd.0006378","article-title":"Efficacy of Aedes aegypti control by indoor ultra low volume (ULV) insecticide spraying in Iquitos, Peru","volume":"12","author":"Gunning","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B41","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s13071-024-06308-3","article-title":"Spatial and temporal analysis on the impact of ultra-low volume indoor insecticide spraying on Aedes aegypti household density","volume":"17","author":"Kawiecki","year":"2024","journal-title":"Parasit Vectors"},{"key":"2025021015551210900_jiae602-B42","doi-asserted-by":"crossref","first-page":"e1007743","DOI":"10.1371\/journal.pcbi.1007743","article-title":"Optimizing the deployment of ultra-low volume and targeted indoor residual spraying for dengue outbreak response","volume":"16","author":"Cavany","year":"2020","journal-title":"PLoS Comput Biol"},{"key":"2025021015551210900_jiae602-B43","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.actatropica.2015.10.020","article-title":"The impact of indoor residual spraying of deltamethrin on dengue vector populations in the Peruvian Amazon","volume":"154","author":"Paredes-Esquivel","year":"2016","journal-title":"Acta Trop"},{"key":"2025021015551210900_jiae602-B44","doi-asserted-by":"crossref","first-page":"e0008097","DOI":"10.1371\/journal.pntd.0008097","article-title":"The impact of insecticide treated curtains on dengue virus transmission: a cluster randomized trial in Iquitos, Peru","volume":"14","author":"Lenhart","year":"2020","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B45","doi-asserted-by":"crossref","first-page":"e2118283119","DOI":"10.1073\/pnas.2118283119","article-title":"Efficacy of a spatial repellent for control of Aedes-borne virus transmission: a cluster-randomized trial in Iquitos, Peru","volume":"119","author":"Morrison","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2025021015551210900_jiae602-B46","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.4269\/ajtmh.15-0096","article-title":"Dengue knowledge and preventive practices in Iquitos, Peru","volume":"93","author":"Paz-Soldan","year":"2015","journal-title":"Am J Trop Med Hyg"},{"key":"2025021015551210900_jiae602-B47","doi-asserted-by":"crossref","first-page":"e0004409","DOI":"10.1371\/journal.pntd.0004409","article-title":"Factors associated with correct and consistent insecticide treated curtain use in Iquitos, Peru","volume":"10","author":"Paz-Soldan","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"key":"2025021015551210900_jiae602-B48","doi-asserted-by":"crossref","first-page":"e0160386","DOI":"10.1371\/journal.pone.0160386","article-title":"Design and testing of novel lethal ovitrap to reduce populations of Aedes mosquitoes: community-based participatory research between industry, academia and communities in Peru and Thailand","volume":"11","author":"Paz-Soldan","year":"2016","journal-title":"PLoS One"},{"key":"2025021015551210900_jiae602-B49","doi-asserted-by":"crossref","first-page":"13","DOI":"10.17843\/rpmesp.2016.331.1900","article-title":"Factors behind people's reluctance towards dengue vector control actions in three districts in northern Peru","volume":"33","author":"Palma-Pinedo","year":"2016","journal-title":"Rev Peru Med Exp Salud Publica"},{"key":"2025021015551210900_jiae602-B50","doi-asserted-by":"crossref","first-page":"e037408","DOI":"10.1136\/bmjopen-2020-037408","article-title":"Cross-sectional study of dengue-related knowledge, attitudes and practices in Villa El Salvador, Lima, Peru","volume":"10","author":"Elson","year":"2020","journal-title":"BMJ Open"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jid\/article-pdf\/231\/Supplement_1\/S31\/61819553\/jiae602.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jid\/article-pdf\/231\/Supplement_1\/S31\/61819553\/jiae602.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T15:55:58Z","timestamp":1739202958000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/231\/Supplement_1\/S31\/8006440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,10]]},"references-count":50,"journal-issue":{"issue":"Supplement_1","published-online":{"date-parts":[[2025,2,10]]},"published-print":{"date-parts":[[2025,2,10]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jiae602","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"value":"0022-1899","type":"print"},{"value":"1537-6613","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,2,15]]},"published":{"date-parts":[[2025,2,10]]}}}