{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:16:26Z","timestamp":1787238986221,"version":"build-2736575974"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We used statewide surveillance data to describe the epidemiology of invasive Haemophilus influenzae type a disease in Alaska during 2018 to 2022. Of 52 cases identified, 39 (75%) occurred among Alaska Native children aged &amp;lt;5 years who lived in rural areas of southwest or northern Alaska. The average annual incidence was 17.8 per 100 000 among children aged &amp;lt;5 years vs 0.3 among persons aged \u22655 years. Among 43 cases in children aged &amp;lt;5 years, 16 (37%) presented with meningitis and 6 (14%) died. Characterizing H influenzae type a disease epidemiology can help direct prevention strategies, including vaccine development and use.<\/jats:p>\n                  <jats:p>From 2018 to 2022, Alaska reported 52 invasive Haemophilus influenzae type a cases, primarily in Alaska Native children aged &amp;lt;5 years in rural areas. The incidence was significantly higher in this group, with notably increased rates of meningitis and mortality.<\/jats:p>","DOI":"10.1093\/infdis\/jiaf132","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T00:17:43Z","timestamp":1741652263000},"page":"e585-e588","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiology of Invasive\n                    <i>Haemophilus influenzae<\/i>\n                    Type a Disease in Alaska, 2018\u20132022"],"prefix":"10.1093","volume":"232","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8388-7062","authenticated-orcid":false,"given":"Tori L","family":"Burket","sequence":"first","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5448-6275","authenticated-orcid":false,"given":"Heather M","family":"Scobie","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2711-4588","authenticated-orcid":false,"given":"Carolynn","family":"DeByle","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Bressler","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5720-4308","authenticated-orcid":false,"given":"Ian","family":"Blake","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3608-5854","authenticated-orcid":false,"given":"Laurie","family":"Orell","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1572-3812","authenticated-orcid":false,"given":"Stephanie","family":"Massay","sequence":"additional","affiliation":[{"name":"Alaska Department of Health, Section of Epidemiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1948-9531","authenticated-orcid":false,"given":"Dana","family":"Bruden","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin P","family":"Westley","sequence":"additional","affiliation":[{"name":"Alaska Native Tribal Health Consortium , Infectious Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph B","family":"McLaughlin","sequence":"additional","affiliation":[{"name":"Alaska Department of Health, Section of Epidemiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Fischer","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,3,12]]},"reference":[{"key":"2025101515144120400_jiaf132-B1","doi-asserted-by":"crossref","first-page":"e3670","DOI":"10.1093\/cid\/ciaa990","article-title":"Clinical characteristics and adverse clinical outcomes of invasive Haemophilus influenzae serotype a cases\u2014United States, 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