{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T01:55:56Z","timestamp":1783734956294,"version":"3.55.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100031003","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U01IP000480"],"award-info":[{"award-number":["U01IP000480"]}],"id":[{"id":"10.13039\/100031003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001504","name":"New Zealand Ministry of Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001504","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Icosavax"},{"name":"AstraZeneca Group"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Unlike influenza, information on the risk of human metapneumovirus (HMPV) infections in adults with chronic medical conditions (CMCs) is less robust.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The SHIVERS project (Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance) performed a population-based surveillance of acute respiratory illness hospitalizations in Auckland, New Zealand, from 2012 to 2015. In this analysis, we linked these surveillance data to population-based administrative data to estimate the age- and ethnicity-adjusted risk of HMPV-associated hospitalization during the study period among adults by certain CMCs: chronic obstructive pulmonary disease, asthma, congestive heart failure, coronary artery disease, cerebrovascular accidents, diabetes mellitus, and end-stage renal disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Overall, HMPV hospitalization rates were significantly higher across all ages and ethnic groups among adults with CMCs than those without any condition. In imputed analysis, the CMC with the highest risk of HMPV hospitalization across age groups was congestive heart failure (incidence rate ratio [IRR] range, 7.0\u201323.0), followed by coronary artery disease (IRR range, 4.2\u20139.1) and chronic obstructive pulmonary disease (IRR range, 6.7\u201311.9) in adults aged \u226550 years. The CMC with the highest risk of HMPV hospitalization was congestive heart failure in M\u0101ori\/Pacific adults and chronic obstructive pulmonary disease in non-M\u0101ori\/Pacific adults. Adults with \u22652 CMCs had a higher risk than those without CMCs; the risk varied by age group and ethnicity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Adults with specific or \u22652 CMCs are at increased risk of HMPV hospitalizations. Age and ethnicity affect this relationship for some CMCs but not all. Such populations may benefit from future HMPV prevention strategies.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiaf226","type":"journal-article","created":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T07:48:17Z","timestamp":1745740097000},"page":"S59-S68","source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Chronic Medical Conditions on the Risk of Human Metapneumovirus Hospitalizations in New Zealand Adults, 2012\u20132015"],"prefix":"10.1093","volume":"232","author":[{"given":"Nayyereh","family":"Aminisani","sequence":"first","affiliation":[{"name":"Wallaceville Science Centre, Institute of Environmental Science and Research"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Wood","sequence":"additional","affiliation":[{"name":"Wallaceville Science Centre, Institute of Environmental Science and 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