{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T10:00:46Z","timestamp":1773396046140,"version":"3.50.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"National Reference Center for Viral Hepatitis B, C and D"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,17]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We evaluated the ability of the commercial Sentosa SQ Hepatitis C Virus Genotyping Assay to identify the hepatitis C virus (HCV) genotype subtype in patients from The Gambia. Subtype was determined from the Sentosa-generated NS5B sequences using 3 bioanalytical methods: Sentosa SQ HCV Genotyping Assay bioanalytical tool, Geno2pheno, and the National Reference Center in-house method. The Sentosa assay result agreed with the reference method in only 2 of 13 cases. This study highlights the difficulty of correctly identifying HCV subtypes in a region of Africa with a high diversity of HCV genotype 1 and 2 subtypes that may be resistant to antivirals.<\/jats:p>","DOI":"10.1093\/infdis\/jiaf378","type":"journal-article","created":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T11:57:46Z","timestamp":1752926266000},"page":"216-220","source":"Crossref","is-referenced-by-count":0,"title":["Virological Tools Fail to Properly Identify \u201cUnusual\u201d Hepatitis C Virus Subtypes Resistant to Direct-Acting Antiviral Drugs in The Gambia"],"prefix":"10.1093","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8280-3426","authenticated-orcid":false,"given":"Erwan","family":"Vo-Quang","sequence":"first","affiliation":[{"name":"Medical Research Council Unit, The Gambia at London School of Hygiene and Tropical Medicine , Fajara ,","place":["The Gambia"]},{"name":"Team \"Viruses, Hepatology, Cancer\", Institut Mondor de Recherche Biom\u00e9dicale, INSERM U955 , Cr\u00e9teil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Team \"Viruses, Hepatology, Cancer\", Institut Mondor de Recherche Biom\u00e9dicale, INSERM U955 , Cr\u00e9teil ,","place":["France"]},{"name":"National Reference Center for Viral Hepatitis B, C and D, Department of Virology, Henri Mondor Hospital, University of Paris-Est , Cr\u00e9teil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"Ly","sequence":"additional","affiliation":[{"name":"Team \"Viruses, Hepatology, Cancer\", Institut Mondor de Recherche Biom\u00e9dicale, INSERM U955 , Cr\u00e9teil ,","place":["France"]},{"name":"National Reference Center for Viral Hepatitis B, C and D, Department of Virology, Henri Mondor Hospital, University of Paris-Est , Cr\u00e9teil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gibril","family":"Ndow","sequence":"additional","affiliation":[{"name":"Medical Research Council Unit, The Gambia at London School of Hygiene and Tropical Medicine , Fajara ,","place":["The Gambia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Soulier","sequence":"additional","affiliation":[{"name":"Team \"Viruses, Hepatology, Cancer\", Institut Mondor de Recherche Biom\u00e9dicale, INSERM U955 , Cr\u00e9teil ,","place":["France"]},{"name":"National Reference Center for Viral Hepatitis B, C and D, Department of Virology, Henri Mondor Hospital, University of Paris-Est , Cr\u00e9teil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Ndebi","sequence":"additional","affiliation":[{"name":"Team \"Viruses, Hepatology, Cancer\", Institut Mondor de Recherche Biom\u00e9dicale, INSERM U955 , Cr\u00e9teil ,","place":["France"]},{"name":"National Reference Center for Viral Hepatitis B, C and D, Department of Virology, Henri Mondor Hospital, University of Paris-Est , Cr\u00e9teil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Chevaliez","sequence":"additional","affiliation":[{"name":"Team \"Viruses, Hepatology, Cancer\", Institut Mondor de Recherche Biom\u00e9dicale, INSERM U955 , Cr\u00e9teil ,","place":["France"]},{"name":"National Reference Center for Viral Hepatitis B, C and D, Department of Virology, Henri Mondor Hospital, University of Paris-Est , Cr\u00e9teil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sainabou","family":"Drammeh","sequence":"additional","affiliation":[{"name":"Medical Research Council Unit, The Gambia at London School of Hygiene and Tropical Medicine , Fajara ,","place":["The Gambia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Chemin","sequence":"additional","affiliation":[{"name":"Cancer Research Center of Lyon, INSERM U1052, UMR 5286, Centre National de la Recherche Scientifique , Lyon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Leroy","sequence":"additional","affiliation":[{"name":"Team \"Viruses, Hepatology, Cancer\", Institut Mondor de Recherche Biom\u00e9dicale, INSERM U955 , Cr\u00e9teil ,","place":["France"]},{"name":"Department of Hepatology, Henri Mondor Hospital, University of Paris-Est , Cr\u00e9teil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maud","family":"Lemoine","sequence":"additional","affiliation":[{"name":"Medical Research Council Unit, The Gambia at London School of Hygiene and Tropical Medicine , Fajara ,","place":["The Gambia"]},{"name":"Division of Digestive Diseases, Section of Hepatology, 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