{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T11:05:08Z","timestamp":1774263908682,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T00:00:00Z","timestamp":1755820800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI 168306"],"award-info":[{"award-number":["R01 AI 168306"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["K24 AI 182638"],"award-info":[{"award-number":["K24 AI 182638"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000061","name":"Fogarty International Center","doi-asserted-by":"publisher","award":["D43 TW 011826"],"award-info":[{"award-number":["D43 TW 011826"]}],"id":[{"id":"10.13039\/100000061","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Schistosoma haematobium infection may impair female genital mucosal antiviral defense. We sought to determine whether women with S. haematobium infection had higher odds of high-risk human papillomavirus (HR-HPV) persistence, a prerequisite to cervical cancer. We also examined cervicovaginal dysbiosis, which has been linked to HR-HPV persistence and schistosome infection. In 96 Tanzanian women with baseline and 9- to 12-month follow-up samples, we performed HPV genotyping, schistosome antigen quantification, and 16S rRNA sequencing. Both S. haematobium (odds ratio: 4.7 [1.3\u201316.5], P = .017) and Gardnerella-dominant microbiome (P = .049) were associated with HR-HPV persistence, suggesting these factors may contribute to high cervical cancer rates in Africa.<\/jats:p>","DOI":"10.1093\/infdis\/jiaf447","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T11:54:08Z","timestamp":1755777248000},"page":"375-380","source":"Crossref","is-referenced-by-count":2,"title":["Schistosome Infection is Associated With High-Risk Human Papillomavirus Persistence, Together With Altered Cervicovaginal Microbiota"],"prefix":"10.1093","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6128-8840","authenticated-orcid":false,"given":"Crispin","family":"Mukerebe","sequence":"first","affiliation":[{"name":"Mwanza Intervention Trials Unit\/National Institute for Medical Research , Mwanza ,","place":["Tanzania"]},{"name":"Department of Molecular Biology and Biotechnology, College of Natural and Applied Sciences, University of Dar es Salaam , Dar es Salaam ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3777-8911","authenticated-orcid":false,"given":"Alexandra A","family":"Cordeiro","sequence":"additional","affiliation":[{"name":"Center for Global Health, Weill Cornell Medicine , New York, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Aristide","sequence":"additional","affiliation":[{"name":"Center for Global Health, Weill Cornell Medicine , New York, New York ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soledad","family":"Colombe","sequence":"additional","affiliation":[{"name":"Center for Global Health, Weill Cornell Medicine , New York, New York ,","place":["USA"]},{"name":"Department of Public Health, Institute of Tropical Medicine , Antwerp ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brooke W","family":"Bullington","sequence":"additional","affiliation":[{"name":"Center for Global Health, Weill Cornell Medicine , New York, New York ,","place":["USA"]},{"name":"Department of Obstetrics and Gynecology, University of Utah , Salt Lake City, Utah ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Kalluvya","sequence":"additional","affiliation":[{"name":"Department of Medicine, Weill Bugando School of Medicine , Mwanza ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Govert J","family":"van Dam","sequence":"additional","affiliation":[{"name":"Leiden University Center for Infectious Diseases, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia J","family":"de Dood","sequence":"additional","affiliation":[{"name":"Department of Cell and Chemical Biology, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0004-0526","authenticated-orcid":false,"given":"Paul L A M","family":"Corstjens","sequence":"additional","affiliation":[{"name":"Department of Cell and Chemical Biology, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane K","family":"Maganga","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit\/National Institute for Medical Research , Mwanza ,","place":["Tanzania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M","family":"Changalucha","sequence":"additional","affiliation":[{"name":"Mwanza Intervention Trials Unit\/National Institute for Medical Research , Mwanza 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