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Well-conducted real-world observational studies can complement evidence from randomized controlled trials to address critical gaps.<\/jats:p>","DOI":"10.1093\/infdis\/jiaf573","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T13:08:23Z","timestamp":1763039303000},"page":"e857-e861","source":"Crossref","is-referenced-by-count":0,"title":["The Role of Antiviral Treatment of Influenza in Reducing Hospitalizations and Other Severe Outcomes: A Need for More Evidence"],"prefix":"10.1093","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8702-8393","authenticated-orcid":false,"given":"Mark W","family":"Tenforde","sequence":"first","affiliation":[{"name":"Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia 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