{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:42:20Z","timestamp":1783543340831,"version":"3.55.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"6","funder":[{"DOI":"10.13039\/501100021671","name":"US National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021671","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004917","name":"Cancer Prevention and Research Institute of Texas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004917","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Human papillomavirus (HPV) vaccination of US individuals aged 27\u201345 years is recommended through shared clinical decision-making. To enable shared decision-making, we used a microsimulation-based state-transition model to develop and validate a risk-prediction model to identify heterosexual men aged 27\u201345 years at high-risk of acquiring oral HPV-16 infections. A risk model for incident oral HPV-16 infections had good discrimination (AUC = 0.73) and calibration (ratio of expected to the observed number of incident oral HPV-16 infections through age 45 years [E\/O] = 1.01) in internal cross-validation. Compared to vaccinating all men aged 27\u201345, vaccinating 44% of men with highest model-predicted risk would prevent 80% of incident oral HPV-16 infections through age 45 years and reduce the number needed to be vaccinated to prevent 1 infection by 45% (184 vs 100).<\/jats:p>","DOI":"10.1093\/infdis\/jiag038","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:34:51Z","timestamp":1768566891000},"page":"e1341-e1344","source":"Crossref","is-referenced-by-count":1,"title":["Risk-Based Prophylactic Human Papillomavirus Vaccination of Heterosexual US Men Aged 27 to 45 Years for Prevention of Oropharyngeal Cancer"],"prefix":"10.1093","volume":"233","author":[{"given":"Anil K","family":"Chaturvedi","sequence":"first","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, Maryland ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory W","family":"Haber","sequence":"additional","affiliation":[{"name":"Information Technology Laboratory, National Institute of Standards and Technology , Gaithersburg, Maryland ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry I","family":"Graubard","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, Maryland ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li C","family":"Cheung","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, Maryland ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maura L","family":"Gillison","sequence":"additional","affiliation":[{"name":"MD Anderson Cancer Center Department of Thoracic\/Head and Neck Medical Oncology, Division of Cancer Medicine, , Houston, Texas ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4042-4820","authenticated-orcid":false,"given":"Rebecca","family":"Landy","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, Maryland ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"2026061615201488800_jiag038-B1","doi-asserted-by":"crossref","first-page":"698","DOI":"10.15585\/mmwr.mm6832a3","article-title":"Human papillomavirus vaccination for adults: updated recommendations of the Advisory Committee on Immunization Practices","volume":"68","author":"Meites","year":"2019","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2026061615201488800_jiag038-B2","author":"Centers for Disease Control and 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papillomavirus infection in the United States","volume":"178","author":"Laprise","year":"2025","journal-title":"Ann Intern Med"},{"key":"2026061615201488800_jiag038-B9","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1001\/jama.2012.101","article-title":"Prevalence of oral HPV infection in the United States, 2009\u20132010","volume":"307","author":"Gillison","year":"2012","journal-title":"JAMA"},{"key":"2026061615201488800_jiag038-B10","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1158\/0008-5472.CAN-14-2843","article-title":"NHANES 2009\u20132012 findings: association of sexual behaviors with higher prevalence of oral oncogenic human papillomavirus infections in US men","volume":"75","author":"Chaturvedi","year":"2015","journal-title":"Cancer Res"},{"key":"2026061615201488800_jiag038-B11","doi-asserted-by":"crossref","first-page":"5572","DOI":"10.1016\/j.vaccine.2018.07.058","article-title":"Revisiting assumptions about age-based mixing representations in 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