{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:01:00Z","timestamp":1790190060317,"version":"4.1.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"Australian National Health and Medical Research Council (NHMRC) Investigator Grant","doi-asserted-by":"publisher","award":["2016792"],"award-info":[{"award-number":["2016792"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001232","name":"Royal Australasian College of Physicians Research Establishment Fellowship","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001232","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001077","name":"Royal Brisbane and Women\u2019s Hospital Foundation Grant","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001077","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023410","name":"Snow Medical Fellowship","doi-asserted-by":"publisher","award":["2022\/SF167"],"award-info":[{"award-number":["2022\/SF167"]}],"id":[{"id":"10.13039\/501100023410","id-type":"DOI","asserted-by":"publisher"}]},{"name":"CSL Centenary Fellowship"},{"name":"NHMRC Investigator grant","award":["2017436"],"award-info":[{"award-number":["2017436"]}]},{"DOI":"10.13039\/501100004167","name":"Medicines for Malaria Venture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004167","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The zoonotic parasite Plasmodium knowlesi is an increasing cause of human malaria in Southeast Asia. We aimed to develop a P. knowlesi induced blood-stage malaria (IBSM) model to facilitate study of parasite biology, host responses to infection, and activity of antimalarial treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We manufactured and characterized a P. knowlesi parasite bank using the P. knowlesi YH1 strain adapted to grow in human serum, and evaluated this bank in an IBSM study involving four adults intravenously inoculated with P. knowlesi-infected erythrocytes using a dose escalation strategy (10-fold increases from ~2800 parasites). Parasitaemia was monitored by qPCR. All participants received curative treatment with artemether-lumefantrine. Endpoints included safety and infectivity of the P. knowlesi bank.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Two of the four participants developed detectable parasitaemia. Participant two (administered \u223c28 000 parasites) had detectable parasites (approximately 6 parasites\/mL) immediately prior to protocol-defined treatment on day 21. Participant three (administered \u223c280 000 parasites) developed detectable parasites on day 17, peaking at 202 parasites\/mL just after protocol-defined treatment on day 24; the parasite multiplication rate over 32 hours (PMR32) was 2.33 (95% CI 1.66\u20133.25). Participant four (also administered \u223c280 000 parasites) did not become infected. Adverse events were mostly mild and unrelated to the challenge agent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A GMP-grade P. knowlesi YH1-HS parasite bank was successfully manufactured and shown to establish patent infection in humans. The finding that only one of two participants became infected at the highest inoculum dose highlights the potential for this IBSM model to evaluate factors influencing inter-individual variability in susceptibility to infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/infdis\/jiag225","type":"journal-article","created":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T11:13:45Z","timestamp":1776510825000},"page":"e652-e660","source":"Crossref","is-referenced-by-count":0,"title":["Development of an Experimental Human Blood-Stage Model for Studying\n                    <i>Plasmodium knowlesi<\/i>"],"prefix":"10.1093","volume":"234","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7414-5216","authenticated-orcid":false,"given":"Jeremy S E","family":"Gower","sequence":"first","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]},{"name":"Faculty of Health, School of Biomedical Sciences, Queensland University of Technology , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6715-9044","authenticated-orcid":false,"given":"Rebecca","family":"Webster","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5171-819X","authenticated-orcid":false,"given":"Jacob A F","family":"Westaway","sequence":"additional","affiliation":[{"name":"Menzies School of Health Research, Charles Darwin University , Darwin, Northern Territory ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob A","family":"Tickner","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Infectious Diseases Sakzewski Laboratory, Centre for Children\u2019s Health Research, Queensland Children\u2019s Hospital , Brisbane, Queensland ,","place":["Australia"]},{"name":"University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire Y T","family":"Wang","sequence":"additional","affiliation":[{"name":"Queensland Paediatric Infectious Diseases Sakzewski Laboratory, Centre for Children\u2019s Health Research, Queensland Children\u2019s Hospital , Brisbane, Queensland ,","place":["Australia"]},{"name":"University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny M","family":"Peters","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6528-5439","authenticated-orcid":false,"given":"Dean","family":"Andrew","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7914-758X","authenticated-orcid":false,"given":"Angelica F","family":"Tan","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5209-0314","authenticated-orcid":false,"given":"Lachlan","family":"Webb","sequence":"additional","affiliation":[{"name":"Population Health Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam J","family":"Potter","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ria","family":"Woo","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Mathison","sequence":"additional","affiliation":[{"name":"University of Sunshine Coast Clinical Trials , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9858-1578","authenticated-orcid":false,"given":"Nischal","family":"Sahai","sequence":"additional","affiliation":[{"name":"University of Sunshine Coast Clinical Trials , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanhua","family":"Chen","sequence":"additional","affiliation":[{"name":"Australian Defence Force Malaria and Infectious Diseases Institute Drug Resistance and Diagnostics, , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7776-4437","authenticated-orcid":false,"given":"Qin","family":"Cheng","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]},{"name":"Australian Defence Force Malaria and Infectious Diseases Institute Drug Resistance and Diagnostics, , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0268-232X","authenticated-orcid":false,"given":"Michelle J","family":"Boyle","sequence":"additional","affiliation":[{"name":"Burnet Institute Cellular Responses to Disease and Vaccination, , Melbourne, Victoria ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2192-0506","authenticated-orcid":false,"given":"Nicholas M","family":"Anstey","sequence":"additional","affiliation":[{"name":"Menzies School of Health Research, Charles Darwin University , Darwin, Northern Territory ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9914-8352","authenticated-orcid":false,"given":"Matthew J","family":"Grigg","sequence":"additional","affiliation":[{"name":"Menzies School of Health Research, Charles Darwin University , Darwin, Northern Territory ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Woodford","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]},{"name":"Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases , Bethesda, Maryland ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen E","family":"Jennings","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona H","family":"Amante","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]},{"name":"Faculty of Health, School of Biomedical Sciences, Queensland University of Technology , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1066-7960","authenticated-orcid":false,"given":"Bridget E","family":"Barber","sequence":"additional","affiliation":[{"name":"Infection and Inflammation Program, QIMR Berghofer , Brisbane, Queensland ,","place":["Australia"]},{"name":"Faculty of Health, School of Biomedical Sciences, Queensland University of Technology , Brisbane, Queensland ,","place":["Australia"]},{"name":"Menzies School of Health Research, Charles Darwin University , Darwin, Northern Territory ,","place":["Australia"]},{"name":"Infectious Diseases Department, Royal Brisbane & Women\u2019s Hospital , Brisbane, Queensland ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"2026092314174608400_jiag225-B1","doi-asserted-by":"crossref","DOI":"10.30875\/9789287074560","volume-title":"World malaria report 2025","author":"World Health Organization","year":"2025"},{"key":"2026092314174608400_jiag225-B2","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1475-2875-12-8","article-title":"Limitations of microscopy to differentiate Plasmodium species in a region co-endemic for Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi","volume":"12","author":"Barber","year":"2013","journal-title":"Malar J"},{"key":"2026092314174608400_jiag225-B3","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00479-17","article-title":"Controlled human malaria infection: applications, advances, and challenges","volume":"86","author":"Stanisic","year":"2018","journal-title":"Infect Immun"},{"key":"2026092314174608400_jiag225-B4","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S1473-3099(21)00679-4","article-title":"Safety, pharmacokinetics and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, a pilot food effect study, and a volunteer infection study","volume":"22","author":"Barber","year":"2022","journal-title":"Lancet Infect Dis"},{"key":"2026092314174608400_jiag225-B5","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S1473-3099(24)00664-9","article-title":"Safety, tolerability, pharmacokinetics, and antimalarial activity of MMV533: a phase 1a first-in-human, randomised, ascending dose and food effect study, and a phase 1b Plasmodium falciparum volunteer infection study","volume":"25","author":"Bestgen","year":"2025","journal-title":"Lancet Infect Dis"},{"key":"2026092314174608400_jiag225-B6","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aax4489","article-title":"Igm in human immunity to Plasmodium falciparum malaria","volume":"5","author":"Boyle","year":"2019","journal-title":"Sci Adv"},{"key":"2026092314174608400_jiag225-B7","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00895-19","article-title":"Early endothelial activation precedes glycocalyx degradation and microvascular dysfunction in experimentally induced Plasmodium falciparum and P. vivax infection","volume":"88","author":"Woodford","year":"2020","journal-title":"Infect Immun"},{"key":"2026092314174608400_jiag225-B8","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1093\/infdis\/jit394","article-title":"Experimentally induced blood-stage Plasmodium vivax infection in healthy volunteers","volume":"208","author":"McCarthy","year":"2013","journal-title":"J Infect Dis"},{"key":"2026092314174608400_jiag225-B9","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1172\/JCI134923","article-title":"A Plasmodium vivax experimental human infection model for evaluating the efficacy of interventions","volume":"130","author":"Collins","year":"2020","journal-title":"J Clin Invest"},{"key":"2026092314174608400_jiag225-B10","first-page":"948","article-title":"An experimental human blood-stage model for studying Plasmodium malariae infection","volume":"221","author":"Woodford","year":"2019","journal-title":"J Infect Dis"},{"key":"2026092314174608400_jiag225-B11","volume-title":"Contribution exp\u00e9rimentale a l'\u00e9tude de l'immunit\u00e9 dans le paludisme","author":"Ciuca","year":"1955"},{"key":"2026092314174608400_jiag225-B12","first-page":"246","article-title":"A study of monkey-malaria and its experimental transmission to man","volume":"67","author":"Knowles","year":"1932","journal-title":"Ind Med Gaz"},{"key":"2026092314174608400_jiag225-B13","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1136\/bmj.2.3901.662","article-title":"Observations on infection by Plasmodium knowlesi (ape malaria) in the treatment of general paralysis of the insane","volume":"2","author":"van Rooyen","year":"1935","journal-title":"Br Med J"},{"key":"2026092314174608400_jiag225-B14","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1126\/science.149.3686.865.a","article-title":"A naturally acquired quotidian-type malaria in man transferable to monkeys","volume":"149","author":"Chin","year":"1965","journal-title":"Science"},{"key":"2026092314174608400_jiag225-B15","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1038\/ncomms2612","article-title":"Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans","volume":"4","author":"Lim","year":"2013","journal-title":"Nat Commun"},{"key":"2026092314174608400_jiag225-B16","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1126\/science.781840","article-title":"Human malaria parasites in continuous culture","volume":"193","author":"Trager","year":"1976","journal-title":"Science"},{"key":"2026092314174608400_jiag225-B17","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1186\/1475-2875-9-344","article-title":"A TaqMan real-time PCR assay for the detection and quantitation of Plasmodium knowlesi","volume":"9","author":"Divis","year":"2010","journal-title":"Malar J"},{"key":"2026092314174608400_jiag225-B18","doi-asserted-by":"crossref","first-page":"4938","DOI":"10.1128\/AAC.02902-14","article-title":"Flow cytometry-based analysis of artemisinin-resistant Plasmodium falciparum in the ring-stage survival assay","volume":"58","author":"Amaratunga","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"2026092314174608400_jiag225-B19","author":"WorldWide Antimalarial Resistance Network (WWARN)"},{"key":"2026092314174608400_jiag225-B20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143199","article-title":"Reliably detecting clinically important variants requires both combined variant calls and optimized filtering strategies","volume":"10","author":"Field","year":"2015","journal-title":"PLoS One"},{"key":"2026092314174608400_jiag225-B21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0012885","article-title":"Genomic epidemiology of Plasmodium knowlesi reveals putative genetic drivers of adaptation in Malaysia","volume":"19","author":"Westaway","year":"2025","journal-title":"PLoS Negl Trop Dis"},{"key":"2026092314174608400_jiag225-B22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-021-03627-z","article-title":"Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies","volume":"20","author":"Woolley","year":"2021","journal-title":"Malar J"},{"key":"2026092314174608400_jiag225-B23","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1186\/s12916-021-02150-x","article-title":"Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine","volume":"19","author":"Webster","year":"2021","journal-title":"BMC Med"},{"key":"2026092314174608400_jiag225-B24","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1475-2875-10-48","article-title":"A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers","volume":"10","author":"Rockett","year":"2011","journal-title":"Malar J"},{"key":"2026092314174608400_jiag225-B25","doi-asserted-by":"crossref","first-page":"616","DOI":"10.3201\/eid2304.161738","article-title":"Three divergent subpopulations of the malaria parasite Plasmodium knowlesi","volume":"23","author":"Divis","year":"2017","journal-title":"Emerg Infect Dis"},{"key":"2026092314174608400_jiag225-B26","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1017\/S0031182017001329","article-title":"PacBio assembly of a Plasmodium knowlesi genome sequence with hi-C correction and manual annotation of the SICAvar gene family","volume":"145","author":"Lapp","year":"2018","journal-title":"Parasitology"},{"key":"2026092314174608400_jiag225-B27","first-page":"187","article-title":"A preliminary note on the treatment of neuro-syphilis with monkey malaria","volume":"71","author":"Chopra","year":"1936","journal-title":"Ind Med Gaz"},{"key":"2026092314174608400_jiag225-B28","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1097\/00007611-193808000-00027","article-title":"Observations on Plasmodium knowlesi malaria in general paresis","volume":"31","author":"Milam","year":"1938","journal-title":"South Med J"},{"key":"2026092314174608400_jiag225-B29","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1093\/cid\/ciy065","article-title":"Age-related clinical spectrum of Plasmodium knowlesi malaria and predictors of severity","volume":"67","author":"Grigg","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2026092314174608400_jiag225-B30","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/cid\/cis902","article-title":"A prospective comparative study of knowlesi, falciparum and vivax malaria in Sabah, Malaysia: high proportion with severe disease from Plasmodium knowlesi and P. vivax but no mortality with early referral and artesunate therapy","volume":"56","author":"Barber","year":"2013","journal-title":"Clin Infect Dis"},{"key":"2026092314174608400_jiag225-B31","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1093\/infdis\/jix193","article-title":"Effects of aging on parasite biomass, inflammation, endothelial activation and microvascular dysfunction in Plasmodium knowlesi and P. falciparum malaria","volume":"215","author":"Barber","year":"2017","journal-title":"J Infect Dis"},{"key":"2026092314174608400_jiag225-B32","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/s12936-018-2420-4","article-title":"In vitro invasion inhibition assay using antibodies against Plasmodium knowlesi Duffy binding protein alpha and apical membrane antigen protein 1 in human erythrocyte-adapted P. knowlesi A1-H. 1 strain","volume":"17","author":"Muh","year":"2018","journal-title":"Malar J"},{"key":"2026092314174608400_jiag225-B33","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1016\/S2542-5196(17)30031-1","article-title":"Individual-level factors associated with the risk of acquiring human Plasmodium knowlesi malaria in Malaysia: a case-control study","volume":"1","author":"Grigg","year":"2017","journal-title":"Lancet Planet Health"},{"key":"2026092314174608400_jiag225-B34","article-title":"From in vivo to in vitro: dynamic analysis of Plasmodium falciparum var gene expression patterns of patient isolates during adaptation to culture","volume":"6","author":"Zhang","year":"2011","journal-title":"PLoS One"},{"key":"2026092314174608400_jiag225-B35","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.meegid.2005.01.003","article-title":"Proteomic studies of Plasmodium knowlesi SICA variant antigens demonstrate their relationship with P. falciparum EMP1","volume":"6","author":"Korir","year":"2006","journal-title":"Infect Genet Evol"},{"key":"2026092314174608400_jiag225-B36","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.888496","article-title":"Plasmodium knowlesi cytoadhesion involves SICA variant proteins","volume":"12","author":"Peterson","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"2026092314174608400_jiag225-B37","first-page":"17","article-title":"Factors affecting the in vitro culture of Plasmodium falciparum and Plasmodium knowlesi","volume":"57","author":"Butcher","year":"1979","journal-title":"Bull World Health Organ"},{"key":"2026092314174608400_jiag225-B38","first-page":"963","article-title":"Growth rate of Plasmodium falciparum: analysis of parasite growth data from malaria volunteer infection studies","volume":"221","author":"Wockner","year":"2020","journal-title":"J Infect Dis"},{"key":"2026092314174608400_jiag225-B39","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.pt.2016.11.001","article-title":"Plasmodium vivax controlled human malaria infection\u2013progress and prospects","volume":"33","author":"Payne","year":"2017","journal-title":"Trends Parasitol"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jid\/advance-article-pdf\/doi\/10.1093\/infdis\/jiag225\/68130248\/jiag225.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jid\/article-pdf\/234\/3\/e652\/68130248\/jiag225.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jid\/article-pdf\/234\/3\/e652\/68130248\/jiag225.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:17:57Z","timestamp":1790187477000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/234\/3\/e652\/8660344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,22]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,4,22]]},"published-print":{"date-parts":[[2026,9,23]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jiag225","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"value":"0022-1899","type":"print"},{"value":"1537-6613","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9,15]]},"published":{"date-parts":[[2026,4,22]]}}}