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Following the replacement of intravenous immunoglobulin supplementation with immunoglobulin M\/immunoglobulin A\u2013enriched immunoglobulin, no recurrence of CDI was observed during the 24-month follow-up period.<\/jats:p>","DOI":"10.1093\/infdis\/jiag291","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T11:40:08Z","timestamp":1780141208000},"page":"40-42","source":"Crossref","is-referenced-by-count":0,"title":["Immunoglobulin M\/Immunoglobulin A\u2013Enriched Immunoglobulins: A Key to Breaking the Cycle of\n                    <i>Clostridioides difficile<\/i>\n                    Infection Recurrences in Patients With Hypogammaglobulinemia?"],"prefix":"10.1093","volume":"234","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8896-5346","authenticated-orcid":false,"given":"Benjamin","family":"Coiffard","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine and Lung Transplantation, Aix Marseille University, APHM, 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,","place":["France"]},{"name":"Center for Cardiovascular and Nutrition Research (C2VN), Institut national de recherche pour l'agriculture et l'alimentation (INRA) 1260, Institut national de la sant\u00e9 et de la recherche m\u00e9dicale (INSERM) UMR_S 1263, Aix-Marseille University , Marseille ,","place":["France"]},{"name":"Aix-Marseille Universit\u00e9, AP-HM, MEPHI Microbiology Department, , Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Bardin","sequence":"additional","affiliation":[{"name":"Service d'Immunologie, P\u00f4le de Biologie, Biog\u00e9nopole, H\u00f4pital de la Timone, Assistance Publique-H\u00f4pitaux de Marseille (AP-HM) , Marseille ,","place":["France"]},{"name":"Center for Cardiovascular and Nutrition Research (C2VN), Institut national de recherche pour l'agriculture et l'alimentation (INRA) 1260, Institut national de la sant\u00e9 et de la recherche m\u00e9dicale (INSERM) UMR_S 1263, Aix-Marseille University , Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5276-6986","authenticated-orcid":false,"given":"Nadim","family":"Cassir","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, AP-HM, MEPHI Microbiology Department, , Marseille ,","place":["France"]},{"name":"IHU-M\u00e9diterran\u00e9e Infection Infectious Diseases Department, , Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"2026080313223183200_jiag291-B1","doi-asserted-by":"crossref","DOI":"10.1128\/cmr.00135-23","article-title":"Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options","volume":"37","author":"Di Bella","year":"2024","journal-title":"Clin Microbiol 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