{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:29:38Z","timestamp":1792654178680,"version":"4.5.0"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,1,1]]},"DOI":"10.1093\/infdis\/jis646","type":"journal-article","created":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T20:22:29Z","timestamp":1351196549000},"page":"80-88","source":"Crossref","is-referenced-by-count":309,"title":["Behavioral, Virologic, and Immunologic Factors Associated With Acquisition and Severity of Primary Epstein\u2013Barr Virus Infection in University Students"],"prefix":"10.1093","volume":"207","author":[{"suffix":"Jr","given":"Henry H.","family":"Balfour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oludare A.","family":"Odumade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David O.","family":"Schmeling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth D.","family":"Mullan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Ed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Knight","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather E.","family":"Vezina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin A.","family":"Hogquist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,10,24]]},"reference":[{"key":"key\n\t\t\t\t20170511122816_JIS646C1","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/S0140-6736(64)91524-7","article-title":"Virus particles in cultured lymphoblasts from Burkitt's lymphoma","volume":"1","author":"Epstein","year":"1964","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170511122816_JIS646C2","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1073\/pnas.59.1.94","article-title":"Relation of Burkitt's tumor-associated herpes-type virus to infectious mononucleosis","volume":"59","author":"Henle","year":"1968","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170511122816_JIS646C3","first-page":"113","article-title":"Sero-epidemiology of the Epstein-Barr virus: preliminary analysis of an international study - a review","volume":"11","author":"de-The","year":"1975","journal-title":"IARC Sci Publ"},{"key":"key\n\t\t\t\t20170511122816_JIS646C4","first-page":"2442","article-title":"Immunofluorescence, interference, and complement fixation technics in the detection of the herpes-type virus in Burkitt tumor cell lines","volume":"27","author":"Henle","year":"1967","journal-title":"Cancer Res"},{"key":"key\n\t\t\t\t20170511122816_JIS646C5","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1002\/ijc.2910340506","article-title":"Early primary infection and high Epstein-Barr virus antibody titers in Greenland Eskimos at high risk for nasopharyngeal carcinoma","volume":"34","author":"Melbye","year":"1984","journal-title":"Int J Cancer"},{"key":"key\n\t\t\t\t20170511122816_JIS646C6","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1017\/CBO9780511545313.054","article-title":"The epidemiology of EBV and its association with malignant disease","volume-title":"Human herpesviruses: biology, therapy, and immunoprophylaxis","author":"Hjalgrim","year":"2007"},{"key":"key\n\t\t\t\t20170511122816_JIS646C7","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1182\/blood.V98.13.3739","article-title":"Asymptomatic primary Epstein-Barr virus infection occurs in the absence of blood T-cell repertoire perturbations despite high levels of systemic viral load","volume":"98","author":"Silins","year":"2001","journal-title":"Blood"},{"key":"key\n\t\t\t\t20170511122816_JIS646C8","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1086\/491740","article-title":"A prospective clinical study of Epstein-Barr virus and host interactions during acute infectious mononucleosis","volume":"192","author":"Balfour","year":"2005","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170511122816_JIS646C9","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1086\/523815","article-title":"Epstein-Barr virus vaccine for the prevention of infectious mononucleosis\u2014and what else?","volume":"196","author":"Balfour","year":"2007","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170511122816_JIS646C10","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1084\/jem.20112401","article-title":"Primary Epstein-Barr virus infection does not erode preexisting CD8 T cell memory in humans","volume":"209","author":"Odumade","year":"2012","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170511122816_JIS646C11","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.immuni.2008.02.020","article-title":"Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines","volume":"28","author":"Miller","year":"2008","journal-title":"Immunity"},{"key":"key\n\t\t\t\t20170511122816_JIS646C12","doi-asserted-by":"crossref","first-page":"2410","DOI":"10.4049\/jimmunol.173.4.2410","article-title":"CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection","volume":"173","author":"Doisne","year":"2004","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20170511122816_JIS646C13","doi-asserted-by":"crossref","first-page":"e1001051","DOI":"10.1371\/journal.ppat.1001051","article-title":"Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans","volume":"6","author":"Sandalova","year":"2010","journal-title":"PLoS Pathog"},{"key":"key\n\t\t\t\t20170511122816_JIS646C14","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1084\/jem.187.9.1395","article-title":"Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo","volume":"187","author":"Callan","year":"1998","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170511122816_JIS646C15","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1146\/annurev.immunol.25.022106.141553","article-title":"Cellular responses to viral infection in humans: lessons from Epstein-Barr virus","volume":"25","author":"Hislop","year":"2007","journal-title":"Annu Rev Immunol"},{"key":"key\n\t\t\t\t20170511122816_JIS646C16","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1089\/088922201750251981","article-title":"A phase III study of recombinant human interferon gamma to prevent opportunistic infections in advanced HIV disease","volume":"17","author":"Riddell","year":"2001","journal-title":"AIDS Res Hum Retroviruses"},{"key":"key\n\t\t\t\t20170511122816_JIS646C17","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1128\/CMR.00044-10","article-title":"Progress and problems in understanding and managing primary Epstein-Barr virus infections","volume":"24","author":"Odumade","year":"2011","journal-title":"Clin Microbiol Rev"},{"key":"key\n\t\t\t\t20170511122816_JIS646C18","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1086\/505400","article-title":"A cohort study among university students: identification of risk factors for Epstein-Barr virus seroconversion and infectious mononucleosis","volume":"43","author":"Crawford","year":"2006","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20170511122816_JIS646C19","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/1523-1747.ep12499958","article-title":"Subclinical Epstein-Barr virus infection of both the male and female genital tract\u2013indication for sexual transmission","volume":"98","author":"Naher","year":"1992","journal-title":"J Invest.Dermatol"},{"key":"key\n\t\t\t\t20170511122816_JIS646C20","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/S0140-6736(86)90531-3","article-title":"A second site for Epstein-Barr virus shedding: the uterine cervix","volume":"2","author":"Sixbey","year":"1986","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170511122816_JIS646C21","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1365-2141.2005.05452.x","article-title":"The immune response to primary EBV infection: a role for natural killer cells","volume":"129","author":"Williams","year":"2005","journal-title":"Br J Haematol"},{"key":"key\n\t\t\t\t20170511122816_JIS646C22","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.0105-2896.2010.00897.x","article-title":"Heterologous immunity between viruses","volume":"235","author":"Welsh","year":"2010","journal-title":"Immunol Rev"},{"key":"key\n\t\t\t\t20170511122816_JIS646C23","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1093\/bioinformatics\/btm044","article-title":"Simulating Epstein-Barr virus infection with C-ImmSim","volume":"23","author":"Castiglione","year":"2007","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20170511122816_JIS646C24","doi-asserted-by":"crossref","first-page":"e1000496","DOI":"10.1371\/journal.ppat.1000496","article-title":"The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output","volume":"5","author":"Hadinoto","year":"2009","journal-title":"PLoS Pathog"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/207\/1\/80\/16866890\/jis646.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T20:37:20Z","timestamp":1562272640000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article-lookup\/doi\/10.1093\/infdis\/jis646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,24]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,10,24]]},"published-print":{"date-parts":[[2013,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jis646","relation":{},"ISSN":["1537-6613","0022-1899"],"issn-type":[{"value":"1537-6613","type":"electronic"},{"value":"0022-1899","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10,24]]}}}