{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:30:05Z","timestamp":1787941805222,"version":"build-2784847793"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10,15]]},"DOI":"10.1093\/infdis\/jit315","type":"journal-article","created":{"date-parts":[[2013,7,13]],"date-time":"2013-07-13T20:11:25Z","timestamp":1373746285000},"page":"1266-1273","source":"Crossref","is-referenced-by-count":45,"title":["Geographic and Temporal Trends in Antimicrobial Nonsusceptibility in Streptococcus pneumoniae in the Post-vaccine era in the United States"],"prefix":"10.1093","volume":"208","author":[{"given":"Ruth","family":"Link-Gelles","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Lynfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Petit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Schaffner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica M.","family":"Farley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Aragon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megin","family":"Nicols","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pam Daily","family":"Kirley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley","family":"Zansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Jorgensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Billie Anne","family":"Juni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delois","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Lipsitch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,7,12]]},"reference":[{"key":"key\n\t\t\t\t20170511124225_JIT315C1","article-title":"Active Bacterial Core Surveillance report: Streptococcus pneumoniae","author":"Centers for Disease Control and Prevention","year":"2009"},{"key":"key\n\t\t\t\t20170511124225_JIT315C2","first-page":"144","article-title":"Invasive pneumococcal disease in children 5 years after conjugate vaccine introduction\u2014eight states, 1998\u20132005","volume":"57","author":"Centers for Disease Control and Prevention","year":"2008","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"key\n\t\t\t\t20170511124225_JIT315C3","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1056\/NEJM200012283432603","article-title":"Increasing prevalence of multidrug-resistant Streptococcus pneumoniae in the United States","volume":"343","author":"Whitney","year":"2000","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170511124225_JIT315C4","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1001\/jama.286.15.1857","article-title":"Macrolide resistance among invasive Streptococcus pneumoniae isolates","volume":"286","author":"Hyde","year":"2001","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20170511124225_JIT315C5","first-page":"656","article-title":"Geographic variation in penicillin resistance in Streptococcus pneumoniae\u2014selected sites, United States, 1997","volume":"48","year":"1999","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"key\n\t\t\t\t20170511124225_JIT315C6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1128\/JCM.40.1.159-164.2002","article-title":"Importance of local variations in antibiotic consumption and geographical differences of erythromycin and penicillin resistance in Streptococcus pneumoniae","volume":"40","author":"Garcia-Rey","year":"2002","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20170511124225_JIT315C7","doi-asserted-by":"crossref","first-page":"552","DOI":"10.3201\/eid0605.000519","article-title":"Antimicrobial-drug use and changes in resistance in Streptococcus pneumoniae","volume":"6","author":"Diekema","year":"2000","journal-title":"Emerg Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C8","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1097\/00006454-200308001-00004","article-title":"Macrolide resistance: an increasing concern for treatment failure in children","volume":"22","author":"Jacobs","year":"2003","journal-title":"Pediatr Infect Dis J"},{"key":"key\n\t\t\t\t20170511124225_JIT315C9","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1097\/INF.0b013e3181715184","article-title":"The association between antibiotic use in the community and nasopharyngeal carriage of antibiotic-resistant Streptococcus pneumoniae in Bedouin children","volume":"27","author":"Greenberg","year":"2008","journal-title":"Pediatr Infect Dis J"},{"key":"key\n\t\t\t\t20170511124225_JIT315C10","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1093\/cid\/cir443","article-title":"Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996\u20132003","volume":"53","author":"Hicks","year":"2011","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C11","doi-asserted-by":"crossref","first-page":"3646","DOI":"10.1128\/AAC.00234-06","article-title":"Macrolide and azithromycin use are linked to increased macrolide resistance in Streptococcus pneumoniae","volume":"50","author":"Bergman","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20170511124225_JIT315C12","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1086\/528996","article-title":"Population snapshot of emergent Streptococcus pneumoniae serotype 19A in the United States, 2005","volume":"197","author":"Moore","year":"2008","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C13","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1086\/648593","article-title":"Sustained reductions in invasive pneumococcal disease in the era of conjugate vaccine","volume":"201","author":"Pilishvili","year":"2010","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C14","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1086\/650496","article-title":"Increased penicillin nonsusceptibility of nonvaccine-serotype invasive pneumococci other than serotypes 19A and 6A in post-7-valent conjugate vaccine era","volume":"201","author":"Gertz","year":"2010","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C15","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1038\/nm839","article-title":"Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States","volume":"9","author":"McCormick","year":"2003","journal-title":"Nat Med"},{"key":"key\n\t\t\t\t20170511124225_JIT315C16","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1126\/science.1215947","article-title":"Niche and neutral effects of acquired immunity permit coexistence of pneumococcal serotypes","volume":"335","author":"Cobey","year":"2012","journal-title":"Science"},{"key":"key\n\t\t\t\t20170511124225_JIT315C17","article-title":"Centers for Disease Control and Prevention. Active Bacterial Core Surveillance (ABCs) report Streptococcus pneumoniae","year":"2008"},{"key":"key\n\t\t\t\t20170511124225_JIT315C18","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3201\/eid0701.010114","article-title":"Active Bacterial Core Surveillance of the Emerging Infections Program Network","volume":"7","author":"Schuchat","year":"2001","journal-title":"Emerg Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C19","volume-title":"Performance standards for antimicrobial susceptibility testing; twenty-second informational supplement","author":"Clinical and Laboratory Standards Institute","year":"2012"},{"key":"key\n\t\t\t\t20170511124225_JIT315C20","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1128\/AAC.49.5.1965-1972.2005","article-title":"Geographical and ecological analysis of resistance, coresistance, and coupled resistance to antimicrobials in respiratory pathogenic bacteria in Spain","volume":"49","author":"Perez-Trallero","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"key\n\t\t\t\t20170511124225_JIT315C21","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1093\/infdis\/jir755","article-title":"Prevention of antibiotic-nonsusceptible Streptococcus pneumoniae with conjugate vaccines","volume":"205","author":"Hampton","year":"2012","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C22","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1086\/319604","article-title":"Measuring and interpreting associations between antibiotic use and penicillin resistance in Streptococcus pneumoniae","volume":"32","author":"Lipsitch","year":"2001","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C23","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1056\/NEJMoa051642","article-title":"Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae","volume":"354","author":"Kyaw","year":"2006","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170511124225_JIT315C24","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/cid\/cir326","article-title":"Geographic variation in invasive pneumococcal disease following pneumococcal conjugate vaccine introduction in the United States","volume":"53","author":"Rosen","year":"2011","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20170511124225_JIT315C25","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00006454-200301000-00006","article-title":"Impact of the pneumococcal conjugate vaccine on otitis media","volume":"22","author":"Fireman","year":"2003","journal-title":"Pediatr Infect Dis J"},{"key":"key\n\t\t\t\t20170511124225_JIT315C26","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1542\/peds.2007-0619","article-title":"Trends in acute otitis media-related health care utilization by privately insured young children in the United States, 1997\u20132004","volume":"121","author":"Zhou","year":"2008","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20170511124225_JIT315C27","doi-asserted-by":"crossref","first-page":"3650","DOI":"10.1016\/j.vaccine.2010.03.030","article-title":"A dynamic model of pneumococcal infection in the United States: implications for prevention through vaccination","volume":"28","author":"Van Effelterre","year":"2010","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20170511124225_JIT315C28","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1016\/S0140-6736(10)62225-8","article-title":"Serotype replacement in disease after pneumococcal vaccination","volume":"378","author":"Weinberger","year":"2011","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170511124225_JIT315C29","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1097\/00006454-200110000-00008","article-title":"Effect of a conjugate pneumococcal vaccine on the occurrence of respiratory infections and antibiotic use in day-care center attendees","volume":"20","author":"Dagan","year":"2001","journal-title":"Pediatr Infect Dis J"},{"key":"key\n\t\t\t\t20170511124225_JIT315C30","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1098\/rsif.2009.0400","article-title":"What is the mechanism for persistent coexistence of drug-susceptible and drug-resistant strains of Streptococcus pneumoniae?","volume":"7","author":"Colijn","year":"2010","journal-title":"J R Soc Interface"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/208\/8\/1266\/16866049\/jit315.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T05:41:52Z","timestamp":1503553312000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article-lookup\/doi\/10.1093\/infdis\/jit315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,12]]},"references-count":30,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2013,7,12]]},"published-print":{"date-parts":[[2013,10,15]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jit315","relation":{},"ISSN":["1537-6613","0022-1899"],"issn-type":[{"value":"1537-6613","type":"electronic"},{"value":"0022-1899","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7,12]]}}}