{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T14:47:37Z","timestamp":1776782857459,"version":"3.51.2"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3,15]]},"DOI":"10.1093\/infdis\/jix055","type":"journal-article","created":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T13:23:26Z","timestamp":1485782606000},"page":"847-855","source":"Crossref","is-referenced-by-count":34,"title":["Effect of Repeated Vaccination With the Same Vaccine Component Against 2009 Pandemic Influenza A(H1N1) Virus"],"prefix":"10.1093","volume":"215","author":[{"given":"Iv\u00e1n","family":"Mart\u00ednez-Baz","sequence":"first","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra, Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) and"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Madrid, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itziar","family":"Casado","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra, Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) and"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Madrid, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Navascu\u00e9s","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario de Navarra, IdiSNA, Pamplona,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"D\u00edaz-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra, Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aitziber","family":"Aguinaga","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario de Navarra, IdiSNA, Pamplona,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Barrado","sequence":"additional","affiliation":[{"name":"Hospital Garc\u00eda Orcoyen, IdiSNA, Estella,Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josu","family":"Delfrade","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra, Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) and"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Madrid, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Ezpeleta","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario de Navarra, IdiSNA, Pamplona,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Castilla","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra, Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) and"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Madrid, and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,2,7]]},"reference":[{"key":"key\n\t\t\t\t20180328160545_CIT0001","author":"World Health Organization","year":"2014"},{"key":"key\n\t\t\t\t20180328160545_CIT0002","doi-asserted-by":"crossref","first-page":"9047","DOI":"10.1073\/pnas.1118979109","article-title":"Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells","volume":"109","author":"Li","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20180328160545_CIT0003","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nature06890","article-title":"Rapid cloning of high-affinity human monoclonal antibodies against influenza virus","volume":"453","author":"Wrammert","year":"2008","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180328160545_CIT0004","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1093\/cid\/cit060","article-title":"Influenza vaccine effectiveness in the community and the household","volume":"56","author":"Ohmit","year":"2013","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0005","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1093\/cid\/cit736","article-title":"Influenza vaccine effectiveness in the 2011\u20132012 season: protection against each circulating virus and the effect of prior vaccination on estimates","volume":"58","author":"Ohmit","year":"2014","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0006","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/cid\/cit255","article-title":"Stratified estimates of influenza vaccine effectiveness by prior vaccination: caution required","volume":"57","author":"Sullivan","year":"2013","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0007","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1001\/archinte.159.2.182","article-title":"Protection against influenza after annually repeated vaccination: a meta-analysis of serologic and field studies","volume":"159","author":"Beyer","year":"1999","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t20180328160545_CIT0008","doi-asserted-by":"crossref","first-page":"8701","DOI":"10.1073\/pnas.0903427106","article-title":"Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines","volume":"106","author":"Ndifon","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20180328160545_CIT0009","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1093\/cid\/ciu680","article-title":"Impact of repeated vaccination on vaccine effectiveness against influenza A(H3N2) and B during 8 seasons","volume":"59","author":"McLean","year":"2014","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0010","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1093\/infdis\/jiu048","article-title":"Influenza A\/subtype and B\/lineage effectiveness estimates for the 2011\u20132012 trivalent vaccine: cross-season and cross-lineage protection with unchanged vaccine","volume":"210","author":"Skowronski","year":"2014","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0011","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1056\/NEJMoa0906453","article-title":"Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus","volume":"361","author":"Hancock","year":"2009","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180328160545_CIT0012","first-page":"81","article-title":"Recommended viruses for influenza vaccines for use in the 2010\u20132011 northern hemisphere influenza season","volume":"85","author":"World Health Organization","year":"2010","journal-title":"Wkly Epidemiol Rec"},{"key":"key\n\t\t\t\t20180328160545_CIT0013","first-page":"97","article-title":"Recommended composition of influenza virus vaccines for use in the 2015\u20132016 northern hemisphere influenza season","volume":"90","author":"World Health Organization","year":"2015","journal-title":"Wkly Epidemiol Rec"},{"key":"key\n\t\t\t\t20180328160545_CIT0014","doi-asserted-by":"crossref","first-page":"15798","DOI":"10.1073\/pnas.1409171111","article-title":"Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season","volume":"111","author":"Linderman","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20180328160545_CIT0015","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1093\/infdis\/jiw479","article-title":"Antibodies against the current influenza A(H1N1) vaccine strain do not protect some individuals from infection with contemporary circulating influenza A(H1N1) virus strains","volume":"214","author":"Petrie","year":"2016","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0016","author":"European Centre for Disease Prevention and Control","year":"2013"},{"key":"key\n\t\t\t\t20180328160545_CIT0017","doi-asserted-by":"crossref","first-page":"20154","DOI":"10.2807\/ese.17.17.20154-en","article-title":"Use of the vaccination register to evaluate influenza vaccine coverage in seniors in the 2010\/11 influenza season, Navarre, Spain","volume":"17","author":"Aguilar","year":"2012","journal-title":"Euro Surveill"},{"key":"key\n\t\t\t\t20180328160545_CIT0018","doi-asserted-by":"crossref","first-page":"5919","DOI":"10.1016\/j.vaccine.2011.06.063","article-title":"Effectiveness of the monovalent influenza A(H1N1)2009 vaccine in Navarre, Spain, 2009\u20132010: cohort and case-control study","volume":"29","author":"Castilla","year":"2011","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180328160545_CIT0019","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/1471-2458-13-191","article-title":"Effectiveness of the trivalent influenza vaccine in Navarre, Spain, 2010\u20132011: a population-based test-negative case-control study","volume":"13","author":"Mart\u00ednez-Baz","year":"2013","journal-title":"BMC Public Health"},{"key":"key\n\t\t\t\t20180328160545_CIT0020","doi-asserted-by":"crossref","first-page":"20388","DOI":"10.2807\/ese.18.05.20388-en","article-title":"Decline in influenza vaccine effectiveness with time after vaccination, Navarre, Spain, season 2011\/12","volume":"18","author":"Castilla","year":"2013","journal-title":"Euro Surveill"},{"key":"key\n\t\t\t\t20180328160545_CIT0021","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1080\/21645515.2015.1038002","article-title":"Influenza vaccine effectiveness in preventing inpatient and outpatient cases in a season dominated by vaccine-matched influenza B virus","volume":"11","author":"Mart\u00ednez-Baz","year":"2015","journal-title":"Hum Vaccin Immunother"},{"key":"key\n\t\t\t\t20180328160545_CIT0022","doi-asserted-by":"crossref","first-page":"30243","DOI":"10.2807\/1560-7917.ES.2016.21.22.30243","article-title":"Effects of previous episodes of influenza and vaccination in preventing laboratory confirmed influenza in Navarra, Spain, 2013\/14 season","volume":"21","author":"Castilla","year":"2016","journal-title":"Euro Surveill"},{"key":"key\n\t\t\t\t20180328160545_CIT0023","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.vaccine.2016.01.054","article-title":"Effectiveness of subunit influenza vaccination in the 2014\u20132015 season and residual effect of split vaccination in previous seasons","volume":"34","author":"Castilla","year":"2016","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180328160545_CIT0024","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1093\/cid\/cis431","article-title":"A sentinel platform to evaluate influenza vaccine effectiveness and new variant circulation, Canada 2010\u20132011 season","volume":"55","author":"Skowronski","year":"2012","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0025","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1017\/S0950268812002282","article-title":"Effectiveness of trivalent and monovalent influenza vaccines against laboratory-confirmed influenza infection in persons with medically attended influenza-like illness in Bavaria, Germany, 2010\/2011 season","volume":"141","author":"Englund","year":"2013","journal-title":"Epidemiol Infect"},{"key":"key\n\t\t\t\t20180328160545_CIT0026","doi-asserted-by":"crossref","first-page":"3595","DOI":"10.1016\/j.vaccine.2012.03.048","article-title":"Effectiveness of the 2010\u201311 seasonal trivalent influenza vaccine in Spain: cycEVA study","volume":"30","author":"Jim\u00e9nez-Jorge","year":"2012","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180328160545_CIT0027","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1017\/S0950268812001148","article-title":"Age-specific vaccine effectiveness of seasonal 2010\/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom","volume":"141","author":"Pebody","year":"2013","journal-title":"Epidemiol Infect"},{"key":"key\n\t\t\t\t20180328160545_CIT0028","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/S0264-410X(97)00003-0","article-title":"Efficacy of repeated annual immunization with inactivated influenza virus vaccines over a five year period","volume":"15","author":"Keitel","year":"1997","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180328160545_CIT0029","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1093\/infdis\/jiv577","article-title":"Influenza vaccine effectiveness against 2009 pandemic influenza A(H1N1) virus differed by vaccine type during 2013\u20132014 in the United States","volume":"213","author":"Gaglani","year":"2016","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180328160545_CIT0030","doi-asserted-by":"crossref","first-page":"6959","DOI":"10.1016\/j.vaccine.2009.08.101","article-title":"MF59-adjuvanted versus non-adjuvanted influenza vaccines: integrated analysis from a large safety database","volume":"27","author":"Pellegrini","year":"2009","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180328160545_CIT0031","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.vaccine.2015.10.119","article-title":"Effects of repeated annual inactivated influenza vaccination among healthcare personnel on serum hemagglutination inhibition antibody response to A\/Perth\/16\/2009 (H3N2)-like virus during 2010\u201311","volume":"34","author":"Thompson","year":"2016","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180328160545_CIT0032","doi-asserted-by":"crossref","first-page":"316ra192","DOI":"10.1126\/scitranslmed.aad0522","article-title":"Immune history profoundly affects broadly protective B cell responses to influenza","volume":"7","author":"Andrews","year":"2015","journal-title":"Sci Transl Med"},{"key":"key\n\t\t\t\t20180328160545_CIT0033","doi-asserted-by":"crossref","first-page":"7381","DOI":"10.1016\/j.vaccine.2010.09.010","article-title":"Study designs for timely estimation of influenza vaccine effectiveness using European sentinel practitioner networks","volume":"28","author":"Valenciano","year":"2010","journal-title":"Vaccine"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/215\/6\/847\/13924125\/jix055.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T03:54:15Z","timestamp":1522295655000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/215\/6\/847\/2972738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,7]]},"references-count":33,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,2,7]]},"published-print":{"date-parts":[[2017,3,15]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jix055","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"value":"0022-1899","type":"print"},{"value":"1537-6613","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,3,15]]},"published":{"date-parts":[[2017,2,7]]}}}