{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T01:58:13Z","timestamp":1791165493406,"version":"4.1.0"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"2","funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7,15]]},"DOI":"10.1093\/infdis\/jix257","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T15:07:56Z","timestamp":1496156876000},"page":"191-197","source":"Crossref","is-referenced-by-count":31,"title":["Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents"],"prefix":"10.1093","volume":"216","author":[{"given":"Chris P","family":"Verschoor","sequence":"first","affiliation":[{"name":"Department of Pathology and Molecular Medicine,"},{"name":"McMaster Institute of Research on Aging, and"},{"name":"Canadian Longitudinal Study on Aging, Hamilton, Ontario; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Lelic","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Parsons","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Evelegh","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan L","family":"Bramson","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennie","family":"Johnstone","sequence":"additional","affiliation":[{"name":"Public Health Ontario, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark B","family":"Loeb","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine,"},{"name":"Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn M E","family":"Bowdish","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Medicine,"},{"name":"McMaster Institute of Research on Aging, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,5,31]]},"reference":[{"key":"key\n\t\t\t\t20180306115508_CIT0001","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1016\/j.vaccine.2012.05.050","article-title":"Review of the United States universal varicella vaccination program: herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based primarily on the antelope valley varicella active surveillance project data","volume":"31","author":"Goldman","year":"2013","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180306115508_CIT0002","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.mcna.2013.02.002","article-title":"Herpes zoster","volume":"97","author":"O\u2019Connor","year":"2013","journal-title":"Med Clin North Am"},{"key":"key\n\t\t\t\t20180306115508_CIT0003","first-page":"1127","article-title":"Update on herpes zoster vaccination: a family practitioner\u2019s guide","volume":"57","author":"Shapiro","year":"2011","journal-title":"Can Fam Physician"},{"key":"key\n\t\t\t\t20180306115508_CIT0004","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jpain.2004.06.001","article-title":"Development of a measure of the burden of pain due to herpes zoster and postherpetic neuralgia for prevention trials: adaptation of the brief pain inventory","volume":"5","author":"Coplan","year":"2004","journal-title":"J Pain"},{"key":"key\n\t\t\t\t20180306115508_CIT0005","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1086\/528696","article-title":"Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine","volume":"197","author":"Levin","year":"2008","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180306115508_CIT0006","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/infdis\/jiv480","article-title":"Cellular and humoral responses to a second dose of herpes zoster vaccine administered 10 years after the first dose among older adults","volume":"213","author":"Levin","year":"2016","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180306115508_CIT0007","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.bbi.2011.02.001","article-title":"Major depressive disorder and immunity to varicella-zoster virus in the elderly","volume":"25","author":"Irwin","year":"2011","journal-title":"Brain Behav Immun"},{"key":"key\n\t\t\t\t20180306115508_CIT0008","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/21645515.2017.1264834","article-title":"Incidence of herpes zoster and post-herpetic neuralgia in Italy: results from a 3-years population-based study","volume":"13","author":"Alicino","year":"2017","journal-title":"Hum Vaccin Immunother"},{"key":"key\n\t\t\t\t20180306115508_CIT0009","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.jamda.2007.06.001","article-title":"How should nursing homes use vaccine to prevent zoster?","volume":"8","author":"Drinka","year":"2007","journal-title":"J Am Med Dir Assoc"},{"key":"key\n\t\t\t\t20180306115508_CIT0010","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1093\/infdis\/jiw462","article-title":"Immunogenicity of varicella vaccine and immunologic predictors of response in a cohort of elderly nursing home residents","volume":"214","author":"Lelic","year":"2016","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180306115508_CIT0011","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s00403-013-1367-0","article-title":"Role of regulatory T cells in patients with acute herpes zoster and relationship to postherpetic neuralgia","volume":"305","author":"Xing","year":"2013","journal-title":"Arch Dermatol Res"},{"key":"key\n\t\t\t\t20180306115508_CIT0012","doi-asserted-by":"crossref","first-page":"e1006050","DOI":"10.1371\/journal.ppat.1006050","article-title":"Cytomegalovirus-specific IL-10-producing CD4+ T cells are governed by type-I IFN-induced IL-27 and promote virus persistence","volume":"12","author":"Clement","year":"2016","journal-title":"PLoS Pathog"},{"key":"key\n\t\t\t\t20180306115508_CIT0013","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jinf.2013.04.010","article-title":"Safety, humoral and cell-mediated immune responses to herpes zoster vaccine in subjects with diabetes mellitus","volume":"67","author":"Hata","year":"2013","journal-title":"J Infect"},{"key":"key\n\t\t\t\t20180306115508_CIT0014","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1093\/cid\/cis1208","article-title":"Varicella zoster virus-specific immune responses to a herpes zoster vaccine in elderly recipients with major depression and the impact of antidepressant medications","volume":"56","author":"Irwin","year":"2013","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180306115508_CIT0015","doi-asserted-by":"crossref","first-page":"e1005892","DOI":"10.1371\/journal.ppat.1005892","article-title":"Defective T memory cell differentiation after varicella zoster vaccination in older individuals","volume":"12","author":"Qi","year":"2016","journal-title":"PLoS Pathog"},{"key":"key\n\t\t\t\t20180306115508_CIT0016","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.mad.2004.05.003","article-title":"Changes with age in the distribution of a frailty index","volume":"125","author":"Rockwood","year":"2004","journal-title":"Mech Ageing Dev"},{"key":"key\n\t\t\t\t20180306115508_CIT0017","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jim.2005.09.011","article-title":"Maximizing the retention of antigen specific lymphocyte function after cryopreservation","volume":"308","author":"Disis","year":"2006","journal-title":"J Immunol Methods"},{"key":"key\n\t\t\t\t20180306115508_CIT0018","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1093\/nar\/gkn1027","article-title":"Telomere length measurement by a novel monochrome multiplex quantitative PCR method","volume":"37","author":"Cawthon","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t20180306115508_CIT0019","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/jgs.14507","article-title":"T-cell phenotypes predictive of frailty and mortality in elderly nursing home residents","volume":"65","author":"Johnstone","year":"2017","journal-title":"J Am Geriatr Soc"},{"key":"key\n\t\t\t\t20180306115508_CIT0020","doi-asserted-by":"crossref","first-page":"e108481","DOI":"10.1371\/journal.pone.0108481","article-title":"Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents","volume":"9","author":"Johnstone","year":"2014","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180306115508_CIT0021","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1471-2318-14-50","article-title":"Immunosenescence in the nursing home elderly","volume":"14","author":"Johnstone","year":"2014","journal-title":"BMC Geriatr"},{"key":"key\n\t\t\t\t20180306115508_CIT0022","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3389\/fimmu.2016.00041","article-title":"T-cell immunity to influenza in older adults: a pathophysiological framework for development of more effective vaccines","volume":"7","author":"McElhaney","year":"2016","journal-title":"Front Immunol"},{"key":"key\n\t\t\t\t20180306115508_CIT0023","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.vaccine.2005.08.105","article-title":"Antibody response to influenza vaccination in the elderly: a quantitative review","volume":"24","author":"Goodwin","year":"2006","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180306115508_CIT0024","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1086\/502509","article-title":"Antibody response to influenza vaccination in nursing home residents and healthcare workers during four successive seasons in Niigata, Japan","volume":"26","author":"Sato","year":"2005","journal-title":"Infect Control Hosp Epidemiol"},{"key":"key\n\t\t\t\t20180306115508_CIT0025","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000022052","article-title":"Antibody response to 1995\u20131996 influenza vaccine in institutionalized and non-institutionalized elderly women","volume":"45","author":"Iorio","year":"1999","journal-title":"Gerontology"},{"key":"key\n\t\t\t\t20180306115508_CIT0026","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.exger.2003.07.004","article-title":"Response to influenza vaccination in community and in nursing home residing elderly: relation to clinical factors","volume":"38","author":"Muszkat","year":"2003","journal-title":"Exp Gerontol"},{"key":"key\n\t\t\t\t20180306115508_CIT0027","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1447-0594.2010.00641.x","article-title":"Immune response to influenza vaccine in the elderly: association with nutritional and physical status","volume":"11","author":"Sagawa","year":"2011","journal-title":"Geriatr Gerontol Int"},{"key":"key\n\t\t\t\t20180306115508_CIT0028","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1447-0594.2008.00483.x","article-title":"Co-administration of l-cystine and l-theanine enhances efficacy of influenza vaccination in elderly persons: nutritional status-dependent immunogenicity","volume":"8","author":"Miyagawa","year":"2008","journal-title":"Geriatr Gerontol Int"},{"key":"key\n\t\t\t\t20180306115508_CIT0029","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1590\/S1413-86702006000400011","article-title":"Risk factors for poor immune response to influenza vaccination in elderly people","volume":"10","author":"Bellei","year":"2006","journal-title":"Braz J Infect Dis"},{"key":"key\n\t\t\t\t20180306115508_CIT0030","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1002\/jmv.21456","article-title":"Benefits of increasing the dose of influenza vaccine in residents of long-term care facilities: a randomized placebo-controlled trial","volume":"81","author":"Cools","year":"2009","journal-title":"J Med Virol"},{"key":"key\n\t\t\t\t20180306115508_CIT0031","doi-asserted-by":"crossref","first-page":"268ra179","DOI":"10.1126\/scitranslmed.3009892","article-title":"mTOR inhibition improves immune function in the elderly","volume":"6","author":"Mannick","year":"2014","journal-title":"Sci Transl Med"},{"key":"key\n\t\t\t\t20180306115508_CIT0032","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1111\/j.1532-5415.2006.00982.x","article-title":"Nutritional formula improved immune profiles of seniors living in nursing homes","volume":"54","author":"Langkamp-Henken","year":"2006","journal-title":"J Am Geriatr Soc"},{"key":"key\n\t\t\t\t20180306115508_CIT0033","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1111\/j.1532-5415.2009.02563.x","article-title":"Cardiovascular exercise training extends influenza vaccine seroprotection in sedentary older adults: the immune function intervention trial","volume":"57","author":"Woods","year":"2009","journal-title":"J Am Geriatr Soc"},{"key":"key\n\t\t\t\t20180306115508_CIT0034","doi-asserted-by":"crossref","first-page":"B55","DOI":"10.1016\/j.vaccine.2015.03.058","article-title":"Beyond adjuvants: Antagonizing inflammation to enhance vaccine immunity","volume":"33","author":"Alter","year":"2015","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180306115508_CIT0035","doi-asserted-by":"crossref","first-page":"E1056","DOI":"10.1152\/ajpendo.00481.2014","article-title":"Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise","volume":"308","author":"Bukhari","year":"2015","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"key\n\t\t\t\t20180306115508_CIT0036","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/msb.2013.15","article-title":"Apoptosis and other immune biomarkers predict influenza vaccine responsiveness","volume":"9","author":"Furman","year":"2013","journal-title":"Mol Syst Biol"},{"key":"key\n\t\t\t\t20180306115508_CIT0037","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.ebiom.2015.09.036","article-title":"Environmental enteropathy, oral vaccine failure and growth faltering in infants in Bangladesh","volume":"2","author":"Naylor","year":"2015","journal-title":"EBioMedicine"},{"key":"key\n\t\t\t\t20180306115508_CIT0038","doi-asserted-by":"crossref","first-page":"999","DOI":"10.4049\/jimmunol.1400504","article-title":"Effector T cells boost regulatory T cell expansion by IL-2, TNF, OX40, and plasmacytoid dendritic cells depending on the immune context","volume":"194","author":"Baeyens","year":"2015","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20180306115508_CIT0039","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1086\/425323","article-title":"Reducing major cause-specific hospitalization rates and shortening hospital stays after influenza vaccination","volume":"39","author":"Wang","year":"2004","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t20180306115508_CIT0040","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4161\/hv.26858","article-title":"Effectiveness of the influenza vaccine at preventing hospitalization due to acute exacerbation of cardiopulmonary disease in Korea from 2011 to 2012","volume":"10","author":"Seo","year":"2014","journal-title":"Hum Vaccin Immunother"},{"key":"key\n\t\t\t\t20180306115508_CIT0041","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/ejhf.14","article-title":"Influenza vaccine and survival in acute heart failure","volume":"16","author":"Kopel","year":"2014","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180306115508_CIT0042","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jchf.2016.12.007","article-title":"Can vaccinations improve heart failure outcomes? contemporary data and future directions","volume":"5","author":"Bhatt","year":"2017","journal-title":"JACC Heart Fail"},{"key":"key\n\t\t\t\t20180306115508_CIT0043","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.cardfail.2008.11.009","article-title":"Decreased immune responses to influenza vaccination in patients with heart failure","volume":"15","author":"Vardeny","year":"2009","journal-title":"J Card Fail"},{"key":"key\n\t\t\t\t20180306115508_CIT0044","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.cardfail.2013.12.008","article-title":"Lack of persistence of influenza vaccine antibody titers in patients with heart failure","volume":"20","author":"Albrecht","year":"2014","journal-title":"J Card Fail"},{"key":"key\n\t\t\t\t20180306115508_CIT0045","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.vaccine.2003.08.032","article-title":"Effect of congestive heart failure on humoral and ex vivo cellular immune responses to influenza vaccination in older adults","volume":"22","author":"McElhaney","year":"2004","journal-title":"Vaccine"},{"key":"key\n\t\t\t\t20180306115508_CIT0046","doi-asserted-by":"crossref","first-page":"e003688","DOI":"10.1161\/CIRCHEARTFAILURE.116.003688","article-title":"Activated T lymphocytes are essential drivers of pathological remodeling in ischemic heart failure","volume":"10","author":"Bansal","year":"2017","journal-title":"Circ Heart Fail"},{"key":"key\n\t\t\t\t20180306115508_CIT0047","doi-asserted-by":"crossref","first-page":"624","DOI":"10.2459\/JCM.0000000000000372","article-title":"Immunosenescence in patients with chronic systolic heart failure","volume":"17","author":"Xydonas","year":"2016","journal-title":"J Cardiovasc Med"}],"container-title":["The Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jid\/article-pdf\/216\/2\/191\/24263972\/jix257.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T11:55:26Z","timestamp":1520337326000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jid\/article\/216\/2\/191\/3859204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,31]]},"references-count":47,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,5,31]]},"published-print":{"date-parts":[[2017,7,15]]}},"URL":"https:\/\/doi.org\/10.1093\/infdis\/jix257","relation":{},"ISSN":["0022-1899","1537-6613"],"issn-type":[{"value":"0022-1899","type":"print"},{"value":"1537-6613","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,7,15]]},"published":{"date-parts":[[2017,5,31]]}}}