{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:43:29Z","timestamp":1784191409234,"version":"3.55.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T00:00:00Z","timestamp":1555632000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Turku University Hospital Foundation"},{"name":"Turku University Foundation"},{"DOI":"10.13039\/501100006306","name":"Sigrid Jus\u00e9lius Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006306","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Life and Health Medical Association"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Human bocavirus 1 (HBoV1) can persist in nasopharynx and tonsils. Using HBoV1 serology, reverse-transcription polymerase chain reaction (PCR) for detecting messenger RNA (mRNA) and quantitative PCR for HBoV1 genome load count, we studied to what extent the HBoV1 DNA loads in nasopharynx correlate with acute infection markers. Tonsillar tissue, nasopharyngeal aspirate, and serum were obtained from 188 elective adeno-\/tonsillectomy patients. Relatively high loads of HBoV1 DNA were detected in the nasopharynx of 14 (7%) primarily asymptomatic subjects with negative mRNA and\/or serodiagnostic results. Quantitative HBoV1 DNA PCR may have lower specificity than HBoV1 mRNA detection for diagnosing symptomatic infection.<\/jats:p>","DOI":"10.1093\/infdis\/jiz166","type":"journal-article","created":{"date-parts":[[2019,4,7]],"date-time":"2019-04-07T15:07:06Z","timestamp":1554649626000},"page":"589-593","source":"Crossref","is-referenced-by-count":10,"title":["No Correlation Between Nasopharyngeal Human Bocavirus 1 Genome Load and mRNA Detection or Serology in Adeno-\/Tonsillectomy Patients"],"prefix":"10.1093","volume":"220","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0169-2681","authenticated-orcid":false,"given":"Lotta E","family":"Ivaska","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Turku University Hospital and University of Turku, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"Department of Clinical Microbiology, St Olavs Hospital, Trondheim University Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Waris","sequence":"additional","affiliation":[{"name":"Department of Virology and Clinical Virology, Turku University Hospital and University of Turku, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuomo","family":"Puhakka","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Turku University Hospital and University of Turku, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tytti","family":"Vuorinen","sequence":"additional","affiliation":[{"name":"Department of Virology and Clinical Virology, Turku University Hospital and University of Turku, 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