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The kinetics of fecal egg counts in volunteers was assessed with Bayesian multilevel analysis, which revealed an increase between weeks 7 and 13, followed by an egg density plateau of about 1000 eggs\/g of feces. Variation in egg counts was minimal between same-day measurements but varied considerably between days, particularly during the plateau phase. These analyses pave the way for the controlled human hookworm model to accelerate drug and vaccine efficacy studies.<\/jats:p>","DOI":"10.1093\/infdis\/jiz218","type":"journal-article","created":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T11:10:38Z","timestamp":1557486638000},"page":"1044-1048","source":"Crossref","is-referenced-by-count":16,"title":["New Insights Into the Kinetics and Variability of Egg Excretion in Controlled Human Hookworm Infections"],"prefix":"10.1093","volume":"220","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3088-3380","authenticated-orcid":false,"given":"Marie-Astrid","family":"Hoogerwerf","sequence":"first","affiliation":[{"name":"Department of Parasitology, Leiden University Medical Center, Leiden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc E","family":"Coffeng","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the 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