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In this study, we describe an alternative, iron-sulfur cluster-containing L-lactate dehydrogenase (LutACB), that is distinct from the flavoprotein L-lactate dehydrogenase (LldD). Expression of lutACB was found to be positively regulated by iron, whereas lldD was more highly expressed under conditions of iron-limitation. The functional role of LutACB and LldD was reflected in in vitro studies of growth and in the survival of N gonorrhoeae in primary cervical epithelial cells.<\/jats:p>","DOI":"10.1093\/infdis\/jiz468","type":"journal-article","created":{"date-parts":[[2019,9,15]],"date-time":"2019-09-15T19:20:22Z","timestamp":1568575222000},"page":"449-453","source":"Crossref","is-referenced-by-count":23,"title":["Two Distinct L-Lactate Dehydrogenases Play a Role in the Survival of Neisseria gonorrhoeae in Cervical Epithelial Cells"],"prefix":"10.1093","volume":"221","author":[{"given":"Nathan H","family":"Chen","sequence":"first","affiliation":[{"name":"School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl-Lynn Y","family":"Ong","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Biosciences and 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