{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:31:44Z","timestamp":1780389104207,"version":"3.54.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,10,5]],"date-time":"2019-10-05T00:00:00Z","timestamp":1570233600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23HD078153-01A1"],"award-info":[{"award-number":["K23HD078153-01A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1R15AI113457-01A1"],"award-info":[{"award-number":["1R15AI113457-01A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002564","name":"Alternatives Research and Development Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002564","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Valley Research Partnership P12"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In recent studies, the interleukin (IL)-36 cytokines were shown to be elevated in women with non-Lactobacillus-dominated vaginal microbiomes. In this study, we evaluated IL36G expression in clinical samples from women with and without bacterial vaginosis (BV) and a human 3-dimensional cervical epithelial cell model. IL36G expression was significantly elevated in cervicovaginal epithelial cells isolated from BV-positive women and corresponded with increased neutrophil counts relative to BV-negative women. In addition, specific BV-associated bacterial species as well as a polymicrobial cocktail significantly induced IL36G expression in vitro. These findings suggest that IL-36\u03b3 may exhibit an important function in the host response to BV and other sexually transmitted infections.<\/jats:p>","DOI":"10.1093\/infdis\/jiz514","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T12:46:47Z","timestamp":1570106807000},"page":"983-988","source":"Crossref","is-referenced-by-count":29,"title":["Interleukin-36\u03b3 Is Elevated in Cervicovaginal Epithelial Cells in Women With Bacterial Vaginosis and In Vitro After Infection With Microbes Associated With Bacterial Vaginosis"],"prefix":"10.1093","volume":"221","author":[{"given":"Jameson K","family":"Gardner","sequence":"first","affiliation":[{"name":"Department of Basic Medical Sciences, College of Medicine-Phoenix, University of Arizona, Phoenix, Arizona, USA"},{"name":"Molecular and Cellular Biology Graduate Program, School of Life Sciences, Arizona State University, Tempe, Arizona, 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