{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:16:48Z","timestamp":1790335008514,"version":"4.1.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"Supplement_4","license":[{"start":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T00:00:00Z","timestamp":1576713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001677","name":"INSERM","doi-asserted-by":"crossref","award":["ANR-09-MIEN-018-01"],"award-info":[{"award-number":["ANR-09-MIEN-018-01"]}],"id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001677","name":"INSERM","doi-asserted-by":"crossref","award":["ANR-ASTRID-2011"],"award-info":[{"award-number":["ANR-ASTRID-2011"]}],"id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Interferon (IFN) type I plays a critical role in the protection of mice from lethal Nipah virus (NiV) infection, but mechanisms responsible for IFN-I induction remain unknown. In the current study, we demonstrated the critical role of the mitochondrial antiviral signaling protein signaling pathway in IFN-I production and NiV replication in murine embryonic fibroblasts in vitro, and the redundant but essential roles of both mitochondrial antiviral signaling protein and myeloid differentiation primary response 88 adaptors, but not toll\/interleukin-1 receptor\/resistance [TIR] domain\u2013containing adaptor\u2013inducing IFN-\u03b2 (TRIF), in the control of NiV infection in mice. These results reveal potential novel targets for antiviral intervention and help in understanding NiV immunopathogenesis.<\/jats:p>","DOI":"10.1093\/infdis\/jiz602","type":"journal-article","created":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T15:11:34Z","timestamp":1573744294000},"page":"S401-S406","source":"Crossref","is-referenced-by-count":28,"title":["Control of Nipah Virus Infection in Mice by the Host Adaptors Mitochondrial Antiviral Signaling Protein (MAVS) and Myeloid Differentiation Primary Response 88 (MyD88)"],"prefix":"10.1093","volume":"221","author":[{"given":"Mathieu","family":"Iampietro","sequence":"first","affiliation":[{"name":"International Center for Infectiology Research (CIRI), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) Unit\u00e91111, Centre National de la Recherche Scientifique (CNRS) Unit\u00e9s Mixtes de Recherche (UMR5308), University Lyon 1, Lyon, 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