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The impact of urogenital schistosomiasis during pregnancy on birth outcomes and child growth is poorly understood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Risk factors for urogenital schistosomiasis were characterized among 4437 pregnant women enrolled in a cluster-randomized community-based trial in rural Zimbabwe. Infection was defined via urine microscopy (\u22651 S. haematobium egg) and urinalysis (hematuria). Associations between infection and pregnancy outcomes were assessed in case-control analyses using conditional logistic regression. The association of maternal infection with birthweight and length-for-age Z scores (LAZ) at 1 and 18 months of age were assessed using generalized estimating equations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Urogenital schistosomiasis (egg positive and\/or hematuria positive) was detected in 26.8% of pregnant women. Risk factors significantly associated with infection were maternal age, education, marital status, and religion; household drinking water source and latrine; study region; and season. Urogenital schistosomiasis was not significantly associated with adverse pregnancy outcomes (miscarriage, stillbirth, preterm, and small-for-gestational age), birthweight, neonatal death, or LAZ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Including pregnant women in antihelminthic treatment programs would benefit a large number of women in rural Zimbabwe. However, clearance of the low-intensity infections that predominate in this context is unlikely to have additive benefits for pregnancy outcomes or child growth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Trials Registration<\/jats:title><jats:p>NCT01824940.<\/jats:p><\/jats:sec>","DOI":"10.1093\/infdis\/jiz664","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T12:11:04Z","timestamp":1576066264000},"page":"1433-1444","source":"Crossref","is-referenced-by-count":24,"title":["Determinants of Urogenital Schistosomiasis Among Pregnant Women and its Association With Pregnancy Outcomes, Neonatal Deaths, and Child Growth"],"prefix":"10.1093","volume":"223","author":[{"given":"Wellington","family":"Murenjekwa","sequence":"first","affiliation":[{"name":"Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Makasi","sequence":"additional","affiliation":[{"name":"Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8543-2835","authenticated-orcid":false,"given":"Robert","family":"Ntozini","sequence":"additional","affiliation":[{"name":"Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Chasekwa","sequence":"additional","affiliation":[{"name":"Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuda","family":"Mutasa","sequence":"additional","affiliation":[{"name":"Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence H","family":"Moulton","sequence":"additional","affiliation":[{"name":"Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M","family":"Tielsch","sequence":"additional","affiliation":[{"name":"Department of Global Health, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean H","family":"Humphrey","sequence":"additional","affiliation":[{"name":"Zvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe"},{"name":"Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura 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