{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:23:27Z","timestamp":1787009007264,"version":"build-2736575974"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T00:00:00Z","timestamp":1630108800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009104","name":"Department of Health Research, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009104","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007334","name":"Ministry of Health and Family Welfare","doi-asserted-by":"publisher","award":["T.11011\/07\/2019-HR\/E-Office-3207446"],"award-info":[{"award-number":["T.11011\/07\/2019-HR\/E-Office-3207446"]}],"id":[{"id":"10.13039\/501100007334","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lack of effective early screening is a major obstacle for reducing the fatality rate and disease burden of dengue. In light of this, the government of Tamil Nadu has adopted a decentralized dengue screening strategy at the primary healthcare (PHC) facilities using blood platelet count. Our objective was to determine the cost-effectiveness of a decentralized screening strategy for dengue at PHC facilities compared with the current strategy at the tertiary health facility (THC) level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Decision tree analysis followed a hypothetical cohort of 1000 suspected dengue cases entering the model. The cost-effectiveness analysis was performed at a 3% discount rate for the proposed and current strategy. The outcomes are expressed in incremental cost-effectiveness ratios (ICERs) per quality-adjusted life years gained. One-way sensitivity analysis and probabilistic sensitivity analysis were done to check the uncertainty in the outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The proposed strategy was found to be cost-saving and ICER was estimated to be \u221241\u00a0197. PSA showed that the proposed strategy had a 0.84 probability of being an economically dominant strategy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The proposed strategy is cost-saving, however, it is recommended to consider optimal population coverage, costs to economic human resources and collateral benefits of equipment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/inthealth\/ihab045","type":"journal-article","created":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T16:41:04Z","timestamp":1630168864000},"page":"295-308","source":"Crossref","is-referenced-by-count":4,"title":["An economic evaluation of implementing a decentralized dengue screening intervention under the National Vector Borne Disease Control Programme in Tamil Nadu, South India"],"prefix":"10.1093","volume":"14","author":[{"given":"Malaisamy","family":"Muniyandi","sequence":"first","affiliation":[{"name":"Scientist-D & Head, Department of Health Economics, ICMR-National Institute for Research in Tuberculosis, No. 1, Sathyamoorthy Road, Chetpet, Chennai 60003, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagarajan","family":"Karikalan","sequence":"additional","affiliation":[{"name":"Scientist-D & Head, Department of Health Economics, ICMR-National Institute for Research in Tuberculosis, No. 1, Sathyamoorthy Road, Chetpet, Chennai 60003, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karunya","family":"Ravi","sequence":"additional","affiliation":[{"name":"Scientist-D & Head, Department of Health Economics, ICMR-National Institute for Research in Tuberculosis, No. 1, Sathyamoorthy Road, Chetpet, Chennai 60003, 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