{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:23:26Z","timestamp":1787009006620,"version":"build-2736575974"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T00:00:00Z","timestamp":1688083200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007855","name":"Alliance for Health Policy and Systems Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007855","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Eclampsia causes maternal mortality in Nigeria. This study presents the effectiveness of multifaceted interventions that addressed institutional barriers in reducing the incidence and case fatality rates associated with eclampsia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The design was quasi-experimental and the activities implemented at intervention hospitals included a new strategic plan, retraining health providers on eclampsia management protocols, clinical reviews of delivery care and educating pregnant women and their partners. Prospective data were collected monthly on eclampsia and related indicators from study sites over 2\u00a0y. The results were analysed by univariate, bivariate and multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The results show a higher eclampsia rate (5.88% vs 2.45%) and a lower use of partograph and antenatal care (ANC; 17.99% vs 23.42%) in control compared with intervention hospitals, but similar case fatality rates of &amp;lt;1%. Overall, adjusted analysis shows a 63% decrease in the odds of eclampsia at intervention compared with control hospitals. Factors associated with eclampsia were ANC, referral for care from other facilities and older maternal age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We conclude that multifaceted interventions that address challenges associated with managing pre-eclampsia and eclampsia in health facilities can reduce eclampsia occurrence in referral facilities in Nigeria and potential eclampsia death in resource-poor African countries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/inthealth\/ihad044","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T05:09:52Z","timestamp":1686200992000},"page":"293-301","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of a multifaceted intervention to prevent eclampsia and eclampsia-related deaths in Nigerian referral facilities"],"prefix":"10.1093","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8777-2606","authenticated-orcid":false,"given":"Friday","family":"Okonofua","sequence":"first","affiliation":[{"name":"Centre of Excellence in Reproductive Health Innovation, University of Benin , Benin City , Nigeria"},{"name":"Department of Obstetrics and Gynaecology, University of Benin and University of Benin Teaching Hospital , Benin City , Nigeria"},{"name":"Women's Health and Action Research Centre , Benin City , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8305-065X","authenticated-orcid":false,"given":"Bola F","family":"Ekezue","sequence":"additional","affiliation":[{"name":"Broadwell College of Business and Economics, Fayetteville State University , Fayetteville, NC , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3218-5535","authenticated-orcid":false,"given":"Lorretta Favour","family":"Ntoimo","sequence":"additional","affiliation":[{"name":"Women's Health and Action Research Centre , Benin City , Nigeria"},{"name":"Department of Demography and Social Statistics, Federal University Oye-Ekiti , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6311-7239","authenticated-orcid":false,"given":"Victor","family":"Ohenhen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Central Hospital Benin City , Benin City , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6596-3671","authenticated-orcid":false,"given":"Kingsley","family":"Agholor","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology\/Anti-Retroviral Therapy Centre, Central Hospital , Warri, Delta State , 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