{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:16:28Z","timestamp":1790835388985,"version":"4.1.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"Supplement_3","license":[{"start":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T00:00:00Z","timestamp":1703030400000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Worldwide, persons affected by skin Neglected Tropical Diseases (NTDs) may experience stigma and discrimination, which could lead to impaired societal functioning and poor mental wellbeing. Evidence of comorbidity of NTDs and mental health conditions is dominated by Leprosy, largely lacking in post-conflict areas, and rarely disaggregated by sex.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This cross-sectional survey is the first to explore depression, anxiety, stigma, and quality of life amongst people affected by Lymphatic Filariasis, Buruli Ulcer, Onchocerciasis or Leprosy in the Democratic Republic of the Congo. After a census through active case identification, the survey was completed by 118 persons (response rate 94.4%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 58.3% of men and 80.0% of women screened positive for major depressive disorder (PHQ-9). Symptoms indicative of generalised anxiety disorder (GAD-7) were displayed by 54.8% of men and 62.2% of women. Being female, having a disability, experiencing stigma and lower physical quality of life were predictors of depression. Anxiety was predicted by age, physical quality of life, disability (for men only) and environmental quality of life (for women only).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Integrated, intersectoral and gender-sensitive initiatives are needed to respond to the many biopsychosocial challenges that persons affected face.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Contexte<\/jats:title>\n                  <jats:p>Dans le monde entier, les personnes atteintes de maladies tropicales n\u00e9glig\u00e9es (MTN) peuvent faire l'objet d'une stigmatisation et d'une discrimination, ce qui peut entra\u00eener une alt\u00e9ration du fonctionnement de la soci\u00e9t\u00e9 et un mauvais bien-\u00eatre mental. Les preuves de la comorbidit\u00e9 des MTN et des troubles de la sant\u00e9 mentale sont domin\u00e9es par la l\u00e8pre, manquent largement dans les zones post-conflit et sont rarement ventil\u00e9es par sexe.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>M\u00e9thodes utilis\u00e9es<\/jats:title>\n                  <jats:p>Cette enqu\u00eate transversale est la premi\u00e8re \u00e0 explorer la d\u00e9pression, l'anxi\u00e9t\u00e9, la stigmatisation et la qualit\u00e9 de vie chez les personnes atteintes de filariose lymphatique, d'ulc\u00e8re de Buruli, d'onchocercose ou de l\u00e8pre en R\u00e9publique d\u00e9mocratique du Congo. Apr\u00e8s un recensement par identification active des cas, 118 personnes ont r\u00e9pondu \u00e0 l'enqu\u00eate (taux de r\u00e9ponse 94,4%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>R\u00e9sultats<\/jats:title>\n                  <jats:p>Au total, 58,3% des hommes et 80,0% des femmes ont \u00e9t\u00e9 d\u00e9pist\u00e9s positifs pour un trouble d\u00e9pressif majeur (PHQ-9). Des sympt\u00f4mes indiquant un trouble anxieux g\u00e9n\u00e9ralis\u00e9 (GAD-7) ont \u00e9t\u00e9 observ\u00e9s chez 54,8 % des hommes et 62,2 % des femmes. Le fait d'\u00eatre une femme, d'avoir un handicap, d'\u00eatre stigmatis\u00e9 et d'avoir une qualit\u00e9 de vie physique inf\u00e9rieure \u00e9tait un facteur pr\u00e9dictif de la d\u00e9pression. L'anxi\u00e9t\u00e9 \u00e9tait pr\u00e9dite par l'\u00e2ge, la qualit\u00e9 de vie physique, le handicap (pour les hommes uniquement) et la qualit\u00e9 de vie environnementale (pour les femmes uniquement).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Des initiatives int\u00e9gr\u00e9es, intersectorielles et sensibles au genre sont n\u00e9cessaires pour r\u00e9pondre aux nombreux d\u00e9fis biopsychosociaux auxquels sont confront\u00e9es les personnes touch\u00e9es.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Antecedentes<\/jats:title>\n                  <jats:p>En todo el mundo, las personas afectadas por Enfermedades Tropicales Desatendidas (ETD) cut\u00e1neas pueden sufrir estigmatizaci\u00f3n y discriminaci\u00f3n, lo que podr\u00eda conducir a un deterioro del funcionamiento social y a un bienestar mental deficiente. La evidencia cient\u00edfica sobre la comorbilidad de las ETD y las afecciones mentales est\u00e1 dominada por la lepra, en general insuficiente en zonas post-conflicto y rara vez se desglosan por sexo.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>M\u00e9todos<\/jats:title>\n                  <jats:p>Esta encuesta transversal es la primera que explora la depresi\u00f3n, la ansiedad, el estigma y la calidad de vida entre las personas afectadas por la filariasis linf\u00e1tica, la \u00falcera de Buruli, la oncocercosis o la lepra en la Rep\u00fablica Democr\u00e1tica del Congo. Tras un censo mediante identificaci\u00f3n activa de casos, la encuesta fue completada por 118 personas (tasa de respuesta del 94,4%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Resultados<\/jats:title>\n                  <jats:p>En total, el 58,3% de los hombres y el 80,0% de las mujeres arrojaron resultados positivos para el trastorno depresivo mayor (PHQ-9). El 54,8% de los hombres y el 62,2% de las mujeres presentaban s\u00edntomas indicativos de trastorno de ansiedad generalizada (TAG-7). Ser mujer, tener una discapacidad, sufrir estigmatizaci\u00f3n y una menor calidad de vida f\u00edsica fueron factores predictivos de la depresi\u00f3n. La edad, la calidad de vida f\u00edsica, la discapacidad (s\u00f3lo en el caso de los hombres) y la calidad de vida ambiental (s\u00f3lo en el caso de las mujeres) fueron factores predictivos de la ansiedad.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusiones<\/jats:title>\n                  <jats:p>Se necesitan iniciativas integradas, intersectoriales y con perspectiva de g\u00e9nero para responder a los numerosos retos biopsicosociales a los que se enfrentan las personas afectadas.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/inthealth\/ihad084","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T20:51:32Z","timestamp":1703105492000},"page":"iii28-iii36","source":"Crossref","is-referenced-by-count":17,"title":["Mental health, stigma and the quality of life of people affected by neglected tropical diseases of the skin in Kasai Province, Democratic Republic of the Congo: a sex-disaggregated analysis"],"prefix":"10.1093","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7000-3624","authenticated-orcid":false,"given":"Maaike L","family":"Seekles","sequence":"first","affiliation":[{"name":"Liverpool School of Tropical Medicine, Department of International Public Health , Pembroke Place, Liverpool L3 5QA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob K","family":"Kadima","sequence":"additional","affiliation":[{"name":"The Leprosy Mission DRC , Kinshasa , Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ding","sequence":"additional","affiliation":[{"name":"Liverpool School of Tropical Medicine, Department of International Public Health , Pembroke Place, Liverpool L3 5QA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian B","family":"Bulambo","sequence":"additional","affiliation":[{"name":"The Leprosy Mission DRC , Kinshasa , Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy J","family":"Kim","sequence":"additional","affiliation":[{"name":"Effect : Hope, Program Team, Markham , ON L3R 6G1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junior K","family":"Kukola","sequence":"additional","affiliation":[{"name":"The Leprosy Mission DRC , Kinshasa , Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre O L","family":"Omumbu","sequence":"additional","affiliation":[{"name":"The Leprosy Mission DRC , Kinshasa , Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael M","family":"Mulamba","sequence":"additional","affiliation":[{"name":"The Leprosy Mission DRC , Kinshasa , Democratic Republic of the Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motto","family":"Nganda","sequence":"additional","affiliation":[{"name":"Liverpool School of Tropical Medicine, Department of International Public Health , Pembroke Place, Liverpool L3 5QA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie M","family":"Ngenyibungi","sequence":"additional","affiliation":[{"name":"University of Kinshasa , Department of Psychology, Kinshasa H8J56PX, Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent L","family":"Ngondu","sequence":"additional","affiliation":[{"name":"Ministry of Health , Leprosy Programme, Kinshasa, M8R29W2, Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis P","family":"Sabuni","sequence":"additional","affiliation":[{"name":"The Leprosy Mission DRC , Kinshasa , Democratic Republic of the 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