{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:53:06Z","timestamp":1789026786061,"version":"build-2803163510"},"reference-count":72,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Immunology"],"published-print":{"date-parts":[[2009,10,1]]},"DOI":"10.1093\/intimm\/dxp083","type":"journal-article","created":{"date-parts":[[2009,8,27]],"date-time":"2009-08-27T01:25:25Z","timestamp":1251336325000},"page":"1163-1174","source":"Crossref","is-referenced-by-count":6,"title":["Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development"],"prefix":"10.1093","volume":"21","author":[{"given":"K.","family":"Laky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Annaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. J.","family":"Fowlkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,8,26]]},"reference":[{"issue":"16","key":"1_19671445","doi-asserted-by":"publisher","first-page":"9312","DOI":"10.1073\/pnas.161102498","volume":"98","year":"2001","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"13","key":"2_11202794","doi-asserted-by":"publisher","first-page":"7487","DOI":"10.1073\/pnas.131202798","volume":"98","author":"Hadland","year":"2001","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"13","key":"3_19566862","doi-asserted-by":"publisher","first-page":"12876","DOI":"10.1074\/jbc.M311652200","volume":"279","year":"2004","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"4_35412786","first-page":"407","volume":"20","year":"2004","ISSN":"https:\/\/id.crossref.org\/issn\/1097-4180","issn-type":"print"},{"issue":"6","key":"5_17801868","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.4049\/jimmunol.171.6.3019","volume":"171","author":"Palaga","year":"2003","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"6","key":"6_17801853","doi-asserted-by":"crossref","first-page":"2896","DOI":"10.4049\/jimmunol.171.6.2896","volume":"171","author":"Adler","year":"2003","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"7","key":"7_18960060","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1038\/ni1209","volume":"6","author":"Minter","year":"2005","journal-title":"Nature immunology","ISSN":"https:\/\/id.crossref.org\/issn\/1529-2908","issn-type":"print"},{"issue":"5398","key":"8_10707052","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1126\/science.283.5398.91","volume":"283","author":"Qi","year":"1999","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"5549","key":"9_20050511","doi-asserted-by":"publisher","first-page":"2179","DOI":"10.1126\/science.1065412","volume":"294","year":"2001","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"8","key":"10_23360118","doi-asserted-by":"publisher","first-page":"1948","DOI":"10.1093\/emboj\/21.8.1948","volume":"21","author":"Marambaud","year":"2002","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"21","key":"11_19554619","doi-asserted-by":"publisher","first-page":"18736","DOI":"10.1074\/jbc.M201979200","volume":"277","year":"2002","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"51","key":"12_19558871","doi-asserted-by":"publisher","first-page":"49976","DOI":"10.1074\/jbc.M210179200","volume":"277","year":"2002","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"13","key":"13_19682664","doi-asserted-by":"publisher","first-page":"7638","DOI":"10.1073\/pnas.1230693100","volume":"100","year":"2003","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"10","key":"14_19559635","doi-asserted-by":"publisher","first-page":"7751","DOI":"10.1074\/jbc.C200711200","volume":"278","year":"2003","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"36","key":"15_19563378","doi-asserted-by":"publisher","first-page":"34427","DOI":"10.1074\/jbc.M302659200","volume":"278","year":"2003","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"10","key":"16_17533453","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1038\/sj.onc.1206298","volume":"22","author":"Murakami","year":"2003","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"47","key":"17_19558114","doi-asserted-by":"publisher","first-page":"44754","DOI":"10.1074\/jbc.M206872200","volume":"277","year":"2002","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"1","key":"18_28670721","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.bbrc.2007.04.100","volume":"358","author":"Schulte","year":"2007","journal-title":"Biochemical and biophysical research communications","ISSN":"https:\/\/id.crossref.org\/issn\/0006-291X","issn-type":"print"},{"issue":"1","key":"19_5861822","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1021\/jm970621b","volume":"41","author":"Wolfe","year":"1998","journal-title":"Journal of medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2623","issn-type":"print"},{"key":"20_35191059","first-page":"1009","volume":"65","year":"1995","ISSN":"https:\/\/id.crossref.org\/issn\/1873-7544","issn-type":"print"},{"issue":"22","key":"21_10040617","doi-asserted-by":"publisher","first-page":"10758","DOI":"10.1073\/pnas.89.22.10758","volume":"89","author":"Wasco","year":"1992","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"15","key":"22_9837525","doi-asserted-by":"crossref","first-page":"10804","DOI":"10.1016\/S0021-9258(19)50090-4","volume":"267","author":"Konig","year":"1992","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"4","key":"23_14672435","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1016\/S0021-9258(17)41992-2","volume":"269","author":"Slunt","year":"1994","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"2","key":"24_14667751","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/S0021-9258(17)42286-1","volume":"269","author":"Sandbrink","year":"1994","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"19","key":"25_15495266","doi-asserted-by":"crossref","first-page":"14227","DOI":"10.1016\/S0021-9258(17)36778-9","volume":"269","author":"Sandbrink","year":"1994","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"1","key":"26_14492252","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1038\/ng0993-95","volume":"5","author":"Wasco","year":"1993","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"46","key":"27_19558043","doi-asserted-by":"publisher","first-page":"44195","DOI":"10.1074\/jbc.M208110200","volume":"277","year":"2002","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"38","key":"28_19550236","doi-asserted-by":"publisher","first-page":"35235","DOI":"10.1074\/jbc.C100357200","volume":"276","year":"2001","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"11","key":"29_16480465","doi-asserted-by":"crossref","first-page":"6229","DOI":"10.1128\/MCB.16.11.6229","volume":"16","author":"Borg","year":"1996","journal-title":"Molecular and Cellular Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0270-7306","issn-type":"print"},{"issue":"52","key":"30_16135701","doi-asserted-by":"publisher","first-page":"30853","DOI":"10.1074\/jbc.270.52.30853","volume":"270","author":"Zambrano","year":"1995","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"5527","key":"31_11224794","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1126\/science.1058783","volume":"293","author":"Cao","year":"2001","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"1","key":"32_28844511","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.mcn.2007.02.003","volume":"35","author":"Ikin","year":"2007","journal-title":"Molecular and cellular neurosciences","ISSN":"https:\/\/id.crossref.org\/issn\/1044-7431","issn-type":"print"},{"issue":"5","key":"33_19558611","doi-asserted-by":"publisher","first-page":"3767","DOI":"10.1074\/jbc.M108357200","volume":"277","year":"2002","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"17","key":"34_11290289","doi-asserted-by":"crossref","first-page":"6597","DOI":"10.1523\/JNEUROSCI.21-17-06597.2001","volume":"21","author":"Matsuda","year":"2001","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"18","key":"35_23678606","doi-asserted-by":"publisher","first-page":"13833","DOI":"10.1074\/jbc.M610146200","volume":"282","year":"2007","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"7","key":"36_10859741","doi-asserted-by":"crossref","first-page":"5179","DOI":"10.1128\/MCB.19.7.5179","volume":"19","author":"Howell","year":"1999","journal-title":"Molecular and Cellular Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0270-7306","issn-type":"print"},{"key":"37_34106701","first-page":"461","volume":"28","year":"2000","ISSN":"https:\/\/id.crossref.org\/issn\/1097-4199","issn-type":"print"},{"issue":"1 Suppl","key":"38_5975206","doi-asserted-by":"publisher","first-page":"S33","DOI":"10.1016\/S0197-4580(98)00040-2","volume":"19","author":"Nishimoto","year":"1998","journal-title":"Neurobiology of aging","ISSN":"https:\/\/id.crossref.org\/issn\/0197-4580","issn-type":"print"},{"key":"39_19553892","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110286200","year":"2002","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"10","key":"40_17054727","doi-asserted-by":"publisher","first-page":"7102","DOI":"10.1073\/pnas.102192599","volume":"99","author":"Roncarati","year":"2002","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"7","key":"41_16989572","doi-asserted-by":"publisher","first-page":"4697","DOI":"10.1073\/pnas.072033799","volume":"99","year":"2002","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"42_24458988","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3233\/JAD-2000-23-408","volume":"2","year":"2000","journal-title":"J ALZ DIS"},{"issue":"4","key":"43_19684466","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1073\/pnas.0437908100","volume":"100","year":"2003","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"44_17174476","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0092-8674(02)00809-7","volume":"110","author":"Baek","year":"2002","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"3","key":"46_18363372","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.coi.2004.03.009","volume":"16","author":"Robey","year":"2004","journal-title":"Current opinion in immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0952-7915","issn-type":"print"},{"issue":"4","key":"47_15883455","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/0092-8674(95)90073-X","volume":"81","author":"Zheng","year":"1995","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"6","key":"48_5880895","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/S0197-4580(97)00151-6","volume":"18","author":"von Koch","year":"1997","journal-title":"Neurobiology of aging","ISSN":"https:\/\/id.crossref.org\/issn\/0197-4580","issn-type":"print"},{"issue":"2","key":"49_35889485","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1083\/jcb.147.2.277","volume":"147","year":"1999","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"6","key":"50_8516830","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.4049\/jimmunol.127.6.2496","volume":"127","author":"Bruce","year":"1981","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"key":"51_35471976","first-page":"1","volume":"90","year":"1999","ISSN":"https:\/\/id.crossref.org\/issn\/1873-7544","issn-type":"print"},{"issue":"21","key":"52_10526079","first-page":"7951","volume":"20","author":"Heber","year":"2000","journal-title":"Journal of Neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/0270-6474","issn-type":"print"},{"issue":"5","key":"53_15703819","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/0092-8674(94)90066-3","volume":"79","author":"M\u00a0\u00a0ller","year":"1994","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"6","key":"54_23008524","first-page":"776","volume":"9","author":"Durham","year":"2006","journal-title":"Current opinion in drug discovery & development","ISSN":"https:\/\/id.crossref.org\/issn\/1367-6733","issn-type":"print"},{"issue":"4","key":"55_29165452","first-page":"383","volume":"10","author":"Hills","year":"2007","journal-title":"Current opinion in drug discovery & development","ISSN":"https:\/\/id.crossref.org\/issn\/1367-6733","issn-type":"print"},{"issue":"3","key":"56_11056023","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1038\/85059","volume":"4","author":"Luo","year":"2001","journal-title":"Nature neuroscience","ISSN":"https:\/\/id.crossref.org\/issn\/1097-6256","issn-type":"print"},{"issue":"12","key":"57_11193822","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1093\/hmg\/10.12.1317","volume":"10","author":"Roberds","year":"2001","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"3","key":"58_5553948","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1016\/0006-291X(90)90992-V","volume":"166","author":"Kang","year":"1990","journal-title":"Biochemical and biophysical research communications","ISSN":"https:\/\/id.crossref.org\/issn\/0006-291X","issn-type":"print"},{"issue":"1-2","key":"59_9269114","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/0014-5793(90)80861-C","volume":"277","author":"M\u00a0\u00a0nning","year":"1990","journal-title":"FEBS Letters","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3468","issn-type":"print"},{"issue":"5","key":"60_23306818","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1002\/j.1460-2075.1988.tb02952.x","volume":"7","author":"Shivers","year":"1988","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"6415","key":"61_10162543","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1038\/362075a0","volume":"362","author":"Nishimoto","year":"1993","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"7","key":"62_16188872","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1073\/pnas.93.7.2729","volume":"93","author":"O'Bryan","year":"1996","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"63_35471977","first-page":"257","volume":"6","year":"1997","ISSN":"https:\/\/id.crossref.org\/issn\/1097-4180","issn-type":"print"},{"issue":"6","key":"64_21326140","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1182\/blood.V90.6.2217","volume":"90","author":"Schmits","year":"1997","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"issue":"8","key":"65_11350654","doi-asserted-by":"crossref","first-page":"4458","DOI":"10.4049\/jimmunol.167.8.4458","volume":"167","author":"Cheng","year":"2001","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"7","key":"66_10870050","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1093\/intimm\/11.7.1017","volume":"11","author":"Felli","year":"1999","journal-title":"International Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0953-8178","issn-type":"print"},{"issue":"3","key":"67_17475467","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.4049\/jimmunol.170.3.1299","volume":"170","author":"Harman","year":"2003","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"3","key":"68_21324795","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1182\/blood.V88.3.970.970","volume":"88","author":"Hasserjian","year":"1996","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"key":"69_34919815","first-page":"547","volume":"10","year":"1999","ISSN":"https:\/\/id.crossref.org\/issn\/1097-4180","issn-type":"print"},{"key":"70_34939053","first-page":"749","volume":"17","year":"2002","ISSN":"https:\/\/id.crossref.org\/issn\/1097-4180","issn-type":"print"},{"key":"71_35239613","first-page":"611","volume":"20","year":"2004","ISSN":"https:\/\/id.crossref.org\/issn\/1097-4180","issn-type":"print"},{"issue":"9","key":"72_18148342","doi-asserted-by":"crossref","first-page":"5230","DOI":"10.4049\/jimmunol.172.9.5230","volume":"172","author":"Ciofani","year":"2004","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"issue":"4","key":"73_18178437","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/S0092-8674(04)00451-9","volume":"117","author":"Amsen","year":"2004","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"}],"container-title":["International Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/intimm\/article-pdf\/21\/10\/1163\/2621141\/dxp083.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T13:41:31Z","timestamp":1685108491000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/intimm\/article-lookup\/doi\/10.1093\/intimm\/dxp083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,26]]},"references-count":72,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2009,9,24]]},"published-print":{"date-parts":[[2009,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/intimm\/dxp083","relation":{},"ISSN":["0953-8178","1460-2377"],"issn-type":[{"value":"0953-8178","type":"print"},{"value":"1460-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,26]]}}}